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In Vitro Antibacterial Activity of Hydroalcoholic and Aqueous Extracts of Echinophora platyloba against Some Pathogenic Bacteria Related to the Oral Cavity | ||
| Journal of Medicinal plants and By-Products | ||
| مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 07 آذر 1403 اصل مقاله (901.61 K) | ||
| نوع مقاله: Research Paper | ||
| شناسه دیجیتال (DOI): 10.22034/jmpb.2024.366579.1731 | ||
| نویسندگان | ||
| Saman Hosseini1، 2؛ Parisa Kargar3؛ Masoumeh Khanahmadi3؛ Nastaran Kazemi3؛ Kheirollah Yari* 2 | ||
| 1Department of Plant Protection, College of Agriculture, Razi University, Kermanshah, Iran | ||
| 2Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran | ||
| 3Department of Medicinal Plants, Institute of Higher Education, Jihad-e-Daneshgahi, Kermanshah, Iran | ||
| چکیده | ||
| Bacteria's antibiotic resistance has increased due to the use of antibiotics as a treatment strategy for pathogenic bacteria. New substances with relatively stronger antimicrobial properties are being discovered in research. Medicinal plants have become an interesting research topic due to their effectiveness against pathogenic bacteria. This in vitro study aimed to evaluate the antimicrobial properties of Echinophora platyloba DC, hydroalcoholic, and aqueous extracts against some important pathogenic bacteria related to the oral cavity. For this purpose, samples of E. platyloba were collected from western Iran, and their extract was extracted. Subsequently, the antibacterial activity of various concentrations of the extracts was evaluated in vitro. The results showed that hydroalcoholic and aqueous extracts in all concentrations (100, 50, 25, and 12.5%) could significantly inhibit the growth of all bacterial pathogens with a probability level of 1% compared to the negative control (DMSO 100%). Furthermore, at 100% concentration, they were capable of suppressing the growth of bacterial pathogens (Staphylococcus epidermidis, Staphylococcus aureus, Streptococcus mutans, Streptococcus salivarius, and Streptococcus sanguis) with a significant difference (p-value < 0.01) compared to the Gentamicin antibiotic. The MIC ranged from 3.12% to 50% in the present study. Therefore, the current research findings indicate that the aqueous and hydrocolic extracts of E. platyloba have a high potential to inhibit human pathogenic bacteria related to the oral cavity. This study's results will pave the way for developing novel functional pharmaceutical and food products. | ||
| کلیدواژه‌ها | ||
| Antimicrobial؛ Medical plants؛ Human pathogenic Bacteria؛ MIC | ||
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آمار تعداد مشاهده مقاله: 90 تعداد دریافت فایل اصل مقاله: 100 |
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