اخبار و اعلانات

 آمار

تعداد نشریات286
تعداد نشریات سازمان84
تعداد شماره‌ها2,907
تعداد مقالات32,799
تعداد مشاهده مقاله43,053,155
تعداد دریافت فایل اصل مقاله19,656,632
Movahedi, nima, zendehdel, morteza, Vazir, Bita, Hassanpour, Shahin. (1403). Sericin-induced hypophagia mediates via M1 muscarinic, NMDA glutamate and glycine receptors in neonatal chicken. سامانه مدیریت نشریات علمی, 79(5), 1109-1116. doi: 10.32592/ARI.2024.79.5.1109
nima Movahedi; morteza zendehdel; Bita Vazir; Shahin Hassanpour. "Sericin-induced hypophagia mediates via M1 muscarinic, NMDA glutamate and glycine receptors in neonatal chicken". سامانه مدیریت نشریات علمی, 79, 5, 1403, 1109-1116. doi: 10.32592/ARI.2024.79.5.1109
Movahedi, nima, zendehdel, morteza, Vazir, Bita, Hassanpour, Shahin. (1403). 'Sericin-induced hypophagia mediates via M1 muscarinic, NMDA glutamate and glycine receptors in neonatal chicken', سامانه مدیریت نشریات علمی, 79(5), pp. 1109-1116. doi: 10.32592/ARI.2024.79.5.1109
Movahedi, nima, zendehdel, morteza, Vazir, Bita, Hassanpour, Shahin. Sericin-induced hypophagia mediates via M1 muscarinic, NMDA glutamate and glycine receptors in neonatal chicken. سامانه مدیریت نشریات علمی, 1403; 79(5): 1109-1116. doi: 10.32592/ARI.2024.79.5.1109

Sericin-induced hypophagia mediates via M1 muscarinic, NMDA glutamate and glycine receptors in neonatal chicken

Archives of Razi Institute
مقاله 29، دوره 79، شماره 5، آذر و دی 2024، صفحه 1109-1116    اصل مقاله (853.21 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.32592/ARI.2024.79.5.1109
نویسندگان
nima Movahedi1؛ morteza zendehdel* 2؛ Bita Vazir3؛ Shahin Hassanpour4
1Division of Physiology, Department of Basic Sciences, Faculty of Veterinary Medicine, Science and Research Branch, Islamic Azad University, Tehran, Iran
2Department of Basic Sciences, Faculty of Veterinary Medicine, University of Tehran, 14155-6453, Tehran, Iran
3Faculty of Veterinary Medicine, Science and Research Branch, Islamic Azad University, Tehran, Iran
4Division of PhysiologyDepartment of Basic Sciences Faculty of Veterinary Medicine Science and Research Branch Islamic Azad University-Tehran-Iran
چکیده
This study aimed to determine interaction between muscarinic, NMDA glutamate and glycine receptors on sericin-induced hypophagia in neonatal chicken. This study included 6 experiments with 4 groups in each with 11 repeats for each group. In experiment 1, chicken received ICV injection of the saline, sericin (0.5 n m o l), Telenzepine (M 1 muscarinic receptor antagonist, 125 n m o l), and in group 4 co-injection of the sericin and Telenzepine were applied. In experiments 2-6, chicken received ICV injections of the AF-DX116 (M 2 muscarinic receptor antagonist, 125 n m o l), 4-DAMP (M3 muscarinic receptor antagonist, 125 n m o l), PD102807 (M 4 muscarinic receptor antagonist, 125 nmol), MK-801 (NMDA glutamate receptor antagonist, 15 n m o l), and Strychnine (glycine receptor antagonist, 100 nmol) instead of telenzepine. Then the cumulative food intake was measured at 30, 60 and 120 minutes after the injection. According to the results, ICV injection of the sericin (0.5 n m o l) significantly decreased cumulative food intake comparison to control chicken (P < 0 . 0 5). Co-injection of the telenzepine + sericin significantly decreased sericin induced hypophagia (P < 0.05). Co-injection of the MK - 801 + sericin decreased hypophagic effects of the sericin comparison to control chicken (P < 0. 0 5). Co-injection of the strychnine + sericin decreased hypophagic effects of the sericin comparison to control chicken (P < 0. 05). These findings suggested, sericin-induced hypophagia mediates via M1 muscarinic, NMDA glutamate and glycine receptors in neonatal chicken.
کلیدواژه‌ها
Muscarinic؛ Glutamate؛ Glycine؛ Food intake؛ Chicken
مراجع
  1. Honda K. Peripheral regulation of food intake in chickens: adiposity signals, satiety signals and others. World's Poultry Science Journal. 2021;77(2):301-12.
  2. Baghaeikia S, Fallah H, Khodadadi M, Yousefvand S, Mahdavi K, Zendehdel M, Rahmani B. Opioid receptor μ, not δ and κ, modulate food intake induced by ghrelin in laying chickens. Canadian journal of physiology and pharmacology. 2022;100(10):983-92.
  3. Kawano Y, Yating H, Sasaki M, Furuya S. Silk sericin intake leads to increases in L-serine and L-tyrosine levels in the mouse brain and the simultaneous facilitation of brain noradrenergic turnover. Bioscience, Biotechnology, and Biochemistry. 2020;84(2):372-9.
  4. Ghosh S, Rao RS, Nambiar KS, Haragannavar VC, Augustine D, Sowmya SV. Sericin, a dietary additive: Mini review. Journal of Medicine, Radiology, Pathology and Surgery. 2017;4(2):13-7.
  5. Falk S, Lund C, Clemmensen C. Muscarinic receptors in energy homeostasis: Physiology and pharmacology. Basic & Clinical Pharmacology & Toxicology. 2020;126:66-76.
  6. Jeong JH, Lee DK, Jo YH. Cholinergic neurons in the dorsomedial hypothalamus regulate food intake. Molecular metabolism. 2017;6(3):306-12.
  7. Zendehdel M, Lankarani Mohajer L, Hassanpour S. Central muscarinic receptor subtypes (M1 and M3) involved in carbacol-induced hypophagia in neonatal broiler chicken. International Journal of Neuroscience. 2020;130(2):204-11.
  8. Adeli A, Zendehdel M, Babapour V, Panahi N. Interaction between leptin and glutamatergic system on food intake regulation in neonatal chicken: role of NMDA and AMPA receptors. International Journal of Neuroscience. 2020;130(7):713-21.
  9. Rahimi J, Zendehdel M, Khodadadi M. Mediatory role of the dopaminergic system through D1 receptor on glycine-induced hypophagia in neonatal broiler-type chickens. Amino Acids. 2021;53(3):461-70.
  10. Shohreh B, Baghbanzadeh A, Zendehdel M. The role of glycine and NMDA glutamate receptor on central regulation of feed intake in broiler cockerels. Journal of Veterinary Research. 2014;69(2): 197-201.
  11. Jonaidi H, Abbassi L, Yaghoobi MM, Kaiya H, Denbow DM, Kamali Y, Shojaei B. The role of GABAergic system on the inhibitory effect of ghrelin on food intake in neonatal chicks. Neuroscience letters. 2012;520(1):82-6.
  12. Saito ES, Kaiya H, Tachibana T, Tomonaga S, Denbow DM, Kangawa K, Furuse M. Inhibitory effect of ghrelin on food intake is mediated by the corticotropin-releasing factor system in neonatal chicks. Regulatory peptides. 2005;125(1-3):201-8.
  13. Furuse M, Ando R, Bungo T, Shimojo M, Masuda Y. Intracerebroventricular injection of orexins does not stimulate food intake in neonatal chicks. British poultry science. 1999;40(5):698-700.
  14. Yousefi AR, Shojaei M, Zendehdel M. Evaluation the role of central serotonin and 5HT2c serotonin receptor on feed intake in female layer-type Bovans chicken by intracerebroventricular (ICV) injection of Para-chlorophenylalanine and SB242084. Veterinary Researches & Biological Products. 2019;32(1):55-62.
  15. Ampawong S, Isarangkul D, Aramwit P. Sericin improves heart and liver mitochondrial architecture in hypercholesterolaemic rats and maintains pancreatic and adrenal cell biosynthesis. Experimental Cell Research. 2017;358(2):301-14.
  16. Wei ZZ, Weng YJ, Zhang YQ. Investigation of the repairing effect and mechanism of oral degraded sericin on liver injury in type II diabetic rats. Biomolecules. 2022;12(3):444.
  17. Song C, Liu D, Yang S, Cheng L, Xing E, Chen Z. Sericin enhances the insulin‑PI3K/AKT signaling pathway in the liver of a type 2 diabetes rat model. Experimental and Therapeutic Medicine. 2018;16(4):3345-52.
  18. Chen Z, He Y, Song C, Dong Z, Su Z, Xue J. Sericin can reduce hippocampal neuronal apoptosis by activating the Akt signal transduction pathway in a rat model of diabetes mellitus. Neural regeneration research. 2012;7(3):197-201.
  19. Sasaki M, Yamada H, Kato N. Consumption of silk protein, sericin elevates intestinal absorption of zinc, iron, magnesium and calcium in rats. Nutrition Research. 2000;20(10):1505-11.
  20. Okazaki Y, Kakehi S, Xu Y, Tsujimoto K, Sasaki M, Ogawa H, Kato N. Consumption of sericin reduces serum lipids, ameliorates glucose tolerance and elevates serum adiponectin in rats fed a high-fat diet. Bioscience, biotechnology, and biochemistry. 2010;74(8):1534-8.
  21. Brown AJ, Bradley SJ, Marshall FH, Brown GA, Bennett KA, Brown J, Cansfield JE, Cross DM, de Graaf C, Hudson BD, Dwomoh L. From structure to clinic: Design of a muscarinic M1 receptor agonist with the potential to treat Alzheimer’s disease. Cell. 2021;184(24):5886-901.
  22. Wolosker H, Sheth KN, Takahashi M, Mothet JP, Brady Jr RO, Ferris CD, Snyder SH. Purification of serine racemase: biosynthesis of the neuromodulator D-serine. Proceedings of the National Academy of Sciences. 1999;96(2):721-5.
  23. Imai H, Moriyasu K, Nakahata A, Maebuchi M, Ichinose T, Furuya S. Soy peptide ingestion augments the synthesis and metabolism of noradrenaline in the mouse brain. Bioscience, Biotechnology, and Biochemistry. 2017;81(5):1007-13.
  24. Bach EC, Halmos KC, Smith BN. Enhanced NMDA receptor-mediated modulation of excitatory neurotransmission in the dorsal vagal complex of streptozotocin-treated, chronically hyperglycemic mice. PloS one. 2015;10(3):e0121022.
  25. Rajani V, Sengar AS, Salter MW. Tripartite signalling by NMDA receptors. Molecular brain. 2020;13(1):23.
آمار
تعداد مشاهده مقاله: 109
تعداد دریافت فایل اصل مقاله: 165


counter
سامانه مدیریت نشریات علمی. طراحی و پیاده سازی از سیناوب