اخبار و اعلانات

 آمار

تعداد نشریات286
تعداد نشریات سازمان84
تعداد شماره‌ها2,932
تعداد مقالات33,084
تعداد مشاهده مقاله43,729,661
تعداد دریافت فایل اصل مقاله20,242,206
Babu MC, Suresh, Choudhary, Akansha, Jacob, Linu, KN, Lokesh, AH, Rudresha, LK, Rajeev, Saldanha, Smitha, Begum, Tarjina. (1403). Breast cancer - Clinicopathological profile at a tertiary cancer center in India. سامانه مدیریت نشریات علمی, 79(6), 1191-1195. doi: 10.32592/ARI.2024.79.6.1191
Suresh Babu MC; Akansha Choudhary; Linu Jacob; Lokesh KN; Rudresha AH; Rajeev LK; Smitha Saldanha; Tarjina Begum. "Breast cancer - Clinicopathological profile at a tertiary cancer center in India". سامانه مدیریت نشریات علمی, 79, 6, 1403, 1191-1195. doi: 10.32592/ARI.2024.79.6.1191
Babu MC, Suresh, Choudhary, Akansha, Jacob, Linu, KN, Lokesh, AH, Rudresha, LK, Rajeev, Saldanha, Smitha, Begum, Tarjina. (1403). 'Breast cancer - Clinicopathological profile at a tertiary cancer center in India', سامانه مدیریت نشریات علمی, 79(6), pp. 1191-1195. doi: 10.32592/ARI.2024.79.6.1191
Babu MC, Suresh, Choudhary, Akansha, Jacob, Linu, KN, Lokesh, AH, Rudresha, LK, Rajeev, Saldanha, Smitha, Begum, Tarjina. Breast cancer - Clinicopathological profile at a tertiary cancer center in India. سامانه مدیریت نشریات علمی, 1403; 79(6): 1191-1195. doi: 10.32592/ARI.2024.79.6.1191

Breast cancer - Clinicopathological profile at a tertiary cancer center in India

Archives of Razi Institute
مقاله 8، دوره 79، شماره 6، بهمن و اسفند 2024، صفحه 1191-1195    اصل مقاله (243.14 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.32592/ARI.2024.79.6.1191
نویسندگان
Suresh Babu MC؛ Akansha Choudhary* ؛ Linu Jacob؛ Lokesh KN؛ Rudresha AH؛ Rajeev LK؛ Smitha Saldanha؛ Tarjina Begum
Department of Medical Oncology, Kidwai Memorial Institute Of Oncology, Bengaluru
چکیده
Breast cancer patients from different regions have different demographics. Therefore, we conducted this study to report the clinicopathological features of breast cancer patients at our center and compare them with information from other studies. This retrospective descriptive study, which included 816 patients registered in the two years between October 2021 and September 2023, was conducted in the Department of Medical Oncology at a Government Tertiary Cancer Care Center in Southern India. At the first presentation, the median age was 49 years old and a majority were post menopausal. Breast lumps were the most frequent presenting complaints, accounting for 636 cases (77.9%) and 115 cases (14.09%) of axillary edema. In 19.9% (162/816) of the patients, a history of breast cancer in the family was evident. Of the patients, 594 had hormone receptor positivity, making up 72.8%. 202 cases, or nearly 25% of the total, were positive for Her 2/neu by FISH or IHC. 178 (21.9%) patients had triple-negative breast cancer (TNBC). The majority of patients (46.8%) presented late in Stage III. In the case of stage IV disease, there were more cases of skeletal metastases (40.3%) than visceral. Our study shows a present scenario of breast cancer patients in Southern India. The majority of patients were post-menopausal. Also, there is an increased number of Hormone receptor-positive patients—more proportion of metastatic disease with skeletal metastasis than other sites. There is a need to increase awareness about breast cancer, alleviate fears, and educate about the importance of screening, timely diagnosis, and treatment. Such studies provide baseline data on the magnitude of the problem and help in looking into the solutions.
کلیدواژه‌ها
Breast cancer؛ female cancer؛ Indian cancer؛ Epidemiology breast cancer؛ common cancer
مراجع
  1. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F: Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71:209-49.
  2. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424.
  3. International Agency for Research on Cancer. India Source: Globocan 2020.
  4. Mathur P, Sathishkumar K, Chaturvedi M, et al.: Cancer Statistics, 2020: report from National Cancer Registry Programme, India. JCO Glob Oncol. 2020;6:1063-75.
  5. Three-Year Report of Population Based Cancer Registries 2012–2014.
  6. Suhani S, Kazi M, Parshad R, Seenu V, Verma E, Mathur S, Gupta SD, Haresh KP. An audit of over 1000 breast cancer patients from a tertiary care center of Northern India. Breast Dis. 2020;39(2):91–99.
  7. Raina V, Bhutani M, Bedi R, Sharma A, Deo SV, Shukla NK et al. Clinical features and prognostic factors of early breast cancer at a major cancer center in North India. Indian J Cancer 2005;42(1):40–5.
  8. Rangarajan B, Shet T, Wadasadawala T, Nair NS, Sairam RM, Hingmire SS, Bajpai J. Breast cancer: an overview of published Indian data. South Asian J Cancer. 2016;5(3):86–92.
  9. Hirko KA, Soliman AS, Hablas A, Seifeldin IA, Ramadan M, Banerjee M, et al. Trends in breast cancer incidence rates by age and stage at diagnosis in Gharbiah, Egypt, over 10 years (1999-2008). J Cancer Epidemiol. 2013;2013:916394.
  10. Bhat MA, Dar AW, Lone MA, Kaneez S, Kuchay S. Sociodemographic and Clinical Profile of Breast Cancer Patients in a Tertiary Care Hospital of Kashmir, India. Int J Sci Stud 2019;7(8):61-65.
  11. Mehrotra R, Yadav K: Breast cancer in India: present scenario and future challenges. World J Clin Oncol. 2022, 13(3):209-18.
  12. Report of National Cancer Registry Programme (2012-2016). 2020:6:1063-1075.
  13. Abdou Y, Gupta M, Asaoka M, Attwood K, Mateusz O, Gandhi S, Takabe K. Left-sided breast cancer is associated with aggressive biology and worse outcomes than right-sided breast cancer. Sci Rep. 2022;12(1):13377.
  14. Meshram II, Hiwarkar PA, Kulkarni PN. Reproductive risk factors for breast cancer: A case-control study. Online J Health Allied Sci 2009;8(3):1-4.
  15. Alwa NAS, Kerr D, Al-Okati D, Pezella F, Tawfeeq FN: Comparative study on the clinicopathological profiles of breast cancer among Iraqi and British patients. Open Public Health J. 2018, 11:177-91.
  16. Cancer in North America: 2012-2016. Volume Three: Registry-specific Cancer Mortality in the United States and Canada. 2023.
  17. Gogia A, Deo SV, Shukla NK, Mathur S, Sharma DN, Tiwari A: Clinicopathological profile of breast cancer: an institutional experience. Indian J Cancer. 2018;55:210-3.
  18. Upadhyay AK, Prakash A. Clinicopathological Profile of Breast Cancer at a Tertiary Cancer Center in Jharkhand, India: A Descriptive Cohort Study. Cureus. 2023;15(6):e39990.
  19. Rathod V, Jha CK, Sinha U. et al. First Comprehensive Report of Clinicopathological Profile of Breast Cancer from Bihar, India. Indian J Surg Oncoll. 2021;12:598–602.20.
  20. Nair N, Shet T, Parmar V, et al.: Breast cancer in a tertiary cancer center in India - an audit, with outcome analysis. Indian J Cancer. 2018, 55:16-22.
  21. Rajan G, Culas TB, Jayalakshmy PS: Estrogen and progesterone receptor status in breast cancer: a cross-sectional study of 450 women in Kerala, South India. World J Surg Oncol. 2014, 12:120.
  22. Datkhile KD, Gudur AK, Gudur RA, Bhosale SJ: A hospital-based cross-sectional study on ER, PR, and Her2 status assessment in breast cancer patients from the tertiary-care hospital of rural Maharashtra. Indian J Cancer. 2022, 59:144-8.
  23. Vaidyanathan K, Kumar P, Reddy CO, Deshmane V, Somasundaram K, Mukherjee G: ErbB-2 expression and its association with other biological parameters of breast cancer among Indian women. Indian J Cancer. 2010;47:8-15.
  24. Dent R, Trudeau M, Pritchard KI, Hanna WM, Kahn HK, Sawka CA, Lickley LA, Rawlinson E, Sun P, Narod SA. Triple-negative breast cancer: clinical features and patterns of recurrence. Clin Cancer Res. 2007;13(15):4429-34.
آمار
تعداد مشاهده مقاله: 118
تعداد دریافت فایل اصل مقاله: 275


counter
سامانه مدیریت نشریات علمی. طراحی و پیاده سازی از سیناوب