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Rusli, Ridho, Darmawan, Arif, Hidayat, Cecep, Krisnan, Rantan. (1404). Evaluation of The Phytochemical Composition and Antimicrobial Properties of Centella asiatica Leaf Meal Extract as a Feed Additive Candidate for Poultry. سامانه مدیریت نشریات علمی, 80(2), 517-524. doi: 10.32592/ARI.2025.80.2.517
Ridho Kurniawan Rusli; Arif Darmawan; Cecep Hidayat; Rantan Krisnan. "Evaluation of The Phytochemical Composition and Antimicrobial Properties of Centella asiatica Leaf Meal Extract as a Feed Additive Candidate for Poultry". سامانه مدیریت نشریات علمی, 80, 2, 1404, 517-524. doi: 10.32592/ARI.2025.80.2.517
Rusli, Ridho, Darmawan, Arif, Hidayat, Cecep, Krisnan, Rantan. (1404). 'Evaluation of The Phytochemical Composition and Antimicrobial Properties of Centella asiatica Leaf Meal Extract as a Feed Additive Candidate for Poultry', سامانه مدیریت نشریات علمی, 80(2), pp. 517-524. doi: 10.32592/ARI.2025.80.2.517
Rusli, Ridho, Darmawan, Arif, Hidayat, Cecep, Krisnan, Rantan. Evaluation of The Phytochemical Composition and Antimicrobial Properties of Centella asiatica Leaf Meal Extract as a Feed Additive Candidate for Poultry. سامانه مدیریت نشریات علمی, 1404; 80(2): 517-524. doi: 10.32592/ARI.2025.80.2.517

Evaluation of The Phytochemical Composition and Antimicrobial Properties of Centella asiatica Leaf Meal Extract as a Feed Additive Candidate for Poultry

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مقاله 28، دوره 80، شماره 2، خرداد و تیر 2025، صفحه 517-524    اصل مقاله (433.68 K)
نوع مقاله: Short Communication
شناسه دیجیتال (DOI): 10.32592/ARI.2025.80.2.517
نویسندگان
Ridho Kurniawan Rusli* 1؛ Arif Darmawan2؛ Cecep Hidayat3؛ Rantan Krisnan3
1Department of Nutrition and Feed Technology, Faculty of Animal Husbandry, Universitas Andalas, Padang, 25175, Indonesia
2Department of Nutrition and Feed Technology, Faculty of Animal Science, IPB University, Bogor, 16680, Indonesia.
3The National Research and Innovation Agency of The Republic of Indonesia.
چکیده
The objective of this study was to assess the phytochemical composition of Centella asiatica leaf meal by analyzing the type of solvent used and the duration of the extraction process. In addition, it assessed the effectiveness of Centella asiatica leaf meal extract as a potential antibacterial agent when added to poultry feed. The study was conducted in two phases. The initial phase employed a fully randomized design featuring a 2 x 5 factorial design and three replications. Factor X denoted the solvent used, which included ordinary distilled water and distilled water heated to 100 oC. Factor Y signified the duration of the extraction process, ranging from 15 to 75 minutes in 15-minute increments. In the second stage, the in vitro antibacterial test was carried out using the most effective extract of Centella asiatica leaf meal as determined in the first stage. The parameters consist of: total phenolic content, total flavonoid content, total tannin content, total antioxidant activity, inhibition zone of Escherichia coli, and Salmonella sp. The results showed a highly significant interaction (p<0.05) between the solvent type and extraction duration on the total phenolic content, flavonoid content, and antioxidant activity. However, the overall tannin concentration remained the same regardless of the solvent used or the duration of the extraction process. Moreover, the extract of Centella asiatica leaf meal extract with a concentration of 100% had a greater inhibition against Escherichia coli and Salmonella sp. bacteria compared to other concentrations. It was concluded that the best extraction method to produce phytochemical compounds from Centella asiatica leaf meal extract is a heated distilled water solvent with 75 minutes of extraction time. Furthermore, Centella asiatica leaf meal extract also has potential as an antibacterial agent candidate for poultry.
کلیدواژه‌ها
antibacterial؛ extraction؛ herbs؛ phytochemical؛ solvents
مراجع
  1. Hidayat C, Sumiati S, Jayanegara A, Wina E. Supplementation of Dietary Nano Zn-Phytogenic on Performance, Antioxidant Activity, and Population of Intestinal Pathogenic Bacteria in Broiler Chickens. Tropical Animal Science Journal. 2021 Mar 9;44(1):90–9.
  2. Rusli R, Mahata M, Yuniza A, Zurmiati, Reski S, Hidayat C, et al. Optimization of Solvent and Extraction Time on Secondary Metabolite Content of Mangosteen Leaf (Garcinia mangostna L.) as a Feed Additive Candidate on Poultry. J Adv Vet Anim Res. 2024, 11(1):139-145.
  3. Kim WJ, Kim J, Veriansyah B, Kim JD, Lee YW, Oh SG, et al. Extraction of bioactive components from Centella asiatica using subcritical water. Journal of Supercritical Fluids. 2009 Apr;48(3):211–6.
  4. Cu On, Fu I, Ja, OJP, PHW. Nutrient and Phytochemical Composition of Centella asiatica Med Aromat Plants (Los Angel). 2020;9(2).
  5. Ajibade OA, Tayo GO, Olumide MD, Akintunde AO. Effect of Centella asiatica as feed additive on blood profile, egg quality and gut microbial contents of ISA brown laying birds. Aceh Journal of Animal Science [Internet]. 2023;8(3):86–93. Available from: www.jurnal.unsyiah.ac.id/AJAS
  6. Calvindi J, Syukur M, Nurcholis W. Investigation of biochemical characters and antioxidant properties of different winged bean (Psophocarpus tetragonolobus) genotypes grown in Indonesia. Biodiversitas. 2020 Jun 1;21(6):2420–4.
  7. Chang C, Yang M, Wen H, Chern J. Estimation of Total Flavonoid Content in Propolis by Two Complementary Colorimetric Methods. J Food Drug Anal. 2002;10(3):178–82.
  8. Kuentzel A. Gerbereichemisches Taschenbuch. Dresden: The Verlag Theodor Steinkopff; 1955.
  9. Melia S, Juliyarsi I, Kurnia YF. Physicochemical properties, sensory characteristics, and antioxidant activity of the goat milk yogurt probiotic Pediococcus acidilactici BK01 on the addition of red ginger (Zingiber officinale var. rubrum rhizoma). Vet World. 2022 Mar 1;15(3):757–64.
  10. Yuniza A, Yuherman. Content of phytochemical compound and antibacterial activity of cinnamon leaf (cinnamomum burmanii) and noni fruit and leaf (Morinda citrifolia L) mixture extract to replace antibiotics. Pakistan Journal of Nutrition. 2015;492–7.
  11. Thoo YY, Ho SK, Liang JY, Ho CW, Tan CP. Effects of binary solvent extraction system, extraction time and extraction temperature on phenolic antioxidants and antioxidant capacity from mengkudu (Morinda citrifolia). Food Chem. 2010 May 1;120(1):290–5.
  12. Wang J, Sun B, Cao Y, Tian Y, Li X. Optimisation of ultrasound-assisted extraction of phenolic compounds from wheat bran. Food Chem. 2008 Jan 15;106(2):804–10.
  13. Abd El-Hack ME, de Oliveira MC, Attia YA, Kamal M, Almohmadi NH, Youssef IM, et al. The efficacy of polyphenols as an antioxidant agent: An updated review. Vol. 250, International Journal of Biological Macromolecules. Elsevier B.V.; 2023.
  14. Chen Y, Chen H, Li W, Miao J, Chen N, Shao X, et al. Polyphenols in Eucalyptus leaves improved the egg and meat qualities and protected against ethanol-induced oxidative damage in laying hens. J Anim Physiol Anim Nutr (Berl). 2018 Feb 1;102(1):214–23.
  15. Silva EM, Rogez H, Larondelle Y. Optimization of extraction of phenolics from Inga edulis leaves using response surface methodology. Sep Purif Technol. 2007 Jul 1;55(3):381–7.
  16. Prihambodo TR, Sholikin MM, Qomariyah N, Jayanegara A, Batubara I, Utomo DB, et al. Effects of dietary flavonoids on performance, blood constituents, carcass composition and small intestinal morphology of broilers: A meta-analysis. Anim Biosci. 2021 Mar 1;34(3):434–42.
  17. Tan Z, Halter B, Liu D, Gilbert ER, Cline MA. Dietary Flavonoids as Modulators of Lipid Metabolism in Poultry. Vol. 13, Frontiers in Physiology. Frontiers Media S.A.; 2022.
  18. Iylia Arina MZ, Harisun Y. Effect of extraction temperatures on tannin content and antioxidant activity of Quercus infectoria (Manjakani). Biocatal Agric Biotechnol. 2019 May 1;19.
  19. Woyengo TA, Nyachoti CM. Ileal digestibility of amino acids for zero-tannin faba bean (Vicia faba L.) fed to broiler chicks. Poult Sci. 2012;91(2):439–43.
  20. Brus M, Gradišnik L, Trapečar M, Škorjanc D, Frangež R. Beneficial effects of water-soluble chestnut (Castanea sativa Mill.) tannin extract on chicken small intestinal epithelial cell culture. Poult Sci. 2018 Apr 1;97(4):1271–82.
  21. Karaffová V, Bobíková K, Levkut M, Revajová V, Ševčíková Z, Levkut M. The influence of Farmatan® and Flimabend® on the mucosal immunity of broiler chicken. Poult Sci. 2019 Mar 1;98(3):1161–6.
  22. Hidayat C, Irawan A, Jayanegara A, Sholikin MM, Prihambodo TR, Yanza YR, et al. Effect of dietary tannins on the performance, lymphoid organ weight, and amino acid ileal digestibility of broiler chickens: A meta-analysis. Vet World. 2021 Jun 1;14(6):1405–11.
  23. Perwiratami C, Suzery M, Cahyono DB. Korelasi Fenolat Total Dan Flavonoid Total Dengan Antioksidan Dari Beberapa Sediaan Ekstrak Buah Tanjung (Mimusops elengi). Vol. 7, Chem. Prog. 2014.
  24. Horváth M, Babinszky L. Impact of selected antioxidant vitamins (Vitamin A, E and C) and micro minerals (Zn, Se) on the antioxidant status and performance under high environmental temperature in poultry. A review. Vol. 68, Acta Agriculturae Scandinavica A: Animal Sciences. Taylor and Francis Ltd.; 2018. p. 152–60.
  25. Patra A, Lalhriatpuii M. Progress and Prospect of Essential Mineral Nanoparticles in Poultry Nutrition and Feeding—a Review. Biol Trace Elem Res. 2020 Sep 1;197(1):233–53.
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