بررسی فیتوشیمی، خواص آنتی‌اکسیدانی و ضدباکتری عصاره اتانولی اندام‌های هوایی و ریشه Tanacetum parthenium L. در مراحل مختلف رشد

Al Akeel, R., Al-Sheikh, Y., Mateen, A., Syed, R., Janardhan, K. and Gupta, V.C., 2014. Evaluation of antibacterial activity of crude protein extracts from seeds of six different medical plants against standard bacterial strains. Saudi journal of biological sciences, 21(2): 147-151.

- Alara, O.R., Abdurahman, N.H. and Olalere, O.A., 2020. Ethanolic extraction of flavonoids, phenolics and antioxidants from Vernonia amygdalina leaf using two-level factorial design. Journal of King Saud University-Science, 32(1): 7-16.

- Andreu, L., Nuncio‐Jáuregui, N., Carbonell‐Barrachina, Á.A., Legua, P. and Hernández, F., 2018. Antioxidant properties and chemical characterization of Spanish Opuntia ficus‐indica Mill. cladodes and fruits. Journal of the Science of Food and Agriculture, 98(4): 1566-1573.

- Anwar, K., Rahmanto, B., Triyasmono, L., Rizki, M.I., Halwany, W. and Lestari, F., 2017. The influence of leaf age on total phenolic, flavonoids, and free radical scavenging capacity of Aquilaria beccariana. Research Journal of Pharmaceutical Biological and Chemical Sciences, 8: 129-133.

- Asadi, S.Y., Zamiri, A., Ezzati, S., Parsaei, P., Rafieian, M. and Shirzad, H., 2011. Effect of alcoholic extract of green tea (Camellia sinensis) on the healing process in surgical and burn wounds in rats. Journal of Birjand Universty Medical Science, 18(1): 1-9.

- Ayan, A.K., Yanar, P., Cirak, C. and Bilgener, M., 2007. Morphogenetic and diurnal variation of total phenols in some Hypericum species from Turkey during their phenological cycles. Bangladesh Journal of Botany, 36(1): 39-46.

- Baranauskiene, R., Venskutonis, P.R., Dambrauskienė, E. and Viškelis, P., 2013. Harvesting time influences the yield and oil composition of Origanum vulgare L. ssp. vulgare and ssp. hirtum. Industrial Crops and Products, 49: 43-51.

- Bekhouche, M., Benyammi, R., Slaoui, M.K., Krimat, S., Paris, C., Khelifi, L. and Morsli, A., 2022. Flavonoid profile and antioxidant properties of Algerian common yew (Taxus baccata L.). Clinical Phytoscience, 8(1): 17-28.

- Cabrita, L., Fossen, T. and Andersen, M., 2000. Colour and stability of the six common anthocyanidin 3-glucosides in aqueous solutions. Food chemistry, 68(1): 101-107.

- Chepel, V., Lisun, V. and Skrypnik, L., 2020. Changes in the content of some groups of phenolic compounds and biological activity of extracts of various parts of heather (Calluna vulgaris (L.) Hull) at different growth stages. Plants, 9(8): 926.

- Chevallier, A., 2001. The Encyclopedia of Medicinal Plants. Dorling Kindersley, London, 336p.

- Cirak, C., Radusiene, J., Camas, N., Caliskan, O. and Odabas, M.S., 2013. Changes in the contents of main secondary metabolites in two Turkish Hypericum species during plant development. Pharmaceutical biology, 51(3): 391-399.

- Cisowska, A., Wojnicz, D. and Hendrich, A.B., 2011. Anthocyanins as antimicrobial agents of natural plant origin. Natural product communications, 6(1): 193-204.

- Coppo, E. and Marchese, A., 2014. Antibacterial activity of polyphenols. Current Pharmaceutical Biotechnology, 15(4): 380-390.

- Cushnie, T.T. and Lamb, A.J., 2011. Recent advances in understanding the antibacterial properties of flavonoids. International journal of antimicrobial agents, 38(2): 99-107.

- Daglia, M., 2012. Polyphenols as antimicrobial agents. Current opinion in biotechnology, 23(2): 174-181.

- Dai, J., Patel, J.D., Mumper, R.J., 2007. Characterization of blackberry extract and its antiproliferative and anti-inflammatory properties. Journal of Medicinal Food, 10: 258-265.

- Debnath, B., Singh, W.S., Das, M., Goswami, S., Singh, M.K., Maiti, D. and Manna, K., 2018. Role of plant alkaloids on human health: A review of biological activities. Materials today chemistry,
9: 56-72.

- Ding, W., Yang, T., Liu, F. and Tian, S., 2014. Effect of different growth stages of Ziziphora clinopodioides Lam. on its chemical composition. Pharmacognosy Magazine, 10(Suppl 1): S1.

- Do, Q.D., Angkawijaya, A.E., Tran-Nguyen, P.L., Huynh, L.H., Soetaredjo, F.E., Ismadji, S. and Ju, Y.H., 2014. Effect of extraction solvent on total phenol content, total flavonoid content, and antioxidant activity of Limnophila aromatica. Journal of food and drug analysis, 22(3): 296-302.

- Farhat, M.B., Jordán, M.J., Chaouch-Hamada, R., Landoulsi, A. and Sotomayor, J.A., 2015. Changes in phenolic profiling and antioxidant capacity of Salvia aegyptiaca L. by-products during three phenological stages. LWT-Food Science and Technology, 63(1): 791-797.

- Gan, J., Feng, Y., He, Z., Li, X. and Zhang, H., 2017. Correlations between antioxidant activity and alkaloids and phenols of Maca (Lepidium meyenii). Journal of Food Quality, 2017: 1-10.

- Girish, H.V. and Satish, S., 2008. Antibacterial Activity of Important Medicinal Plants on Human Pathogenic Bacteria-a Comparative Analysis. World Applied Science Journal, 5(3): 267-271.

- Górniak, I., Bartoszewski, R. and Króliczewski, J., 2019. Comprehensive review of antimicrobial activities of plant flavonoids. Phytochemistry Reviews, 18(1): 241-272.

- Jordán, M.J., Lax, V., Rota, M.C., Lorán, S. and Sotomayor, J.A., 2013. Effect of the phenological stage on the chemical composition, and antimicrobial and antioxidant properties of Rosmarinus officinalis L. essential oil and its polyphenolic extract. Industrial crops and products, 48: 144-152.

- Kähkönen, M.P. and Heinonen, M., 2003. Antioxidant activity of anthocyanins and their aglycons. Journal of Agricultural and Food Chemistry, 51: 628-633.

- Kasera, P.K., Soni, A., Daiya, K. and Sagar, A., 2018. Evaluation of phytochemical variations in medicinal plants of Rajasthan. International Journal of Phytocosmetics and Natural Ingredients, 5(1): 12-21.

- Khalasi Ahwazi, L., Heshmati, G.A., Zofan, P. and Akbarlou, M., 2016. Total phenol, flavonoid contents and antioxidant activity of Gundelia tournefortii L. in different phenological stage and habitats of North East of khozestan province.
Ecophytochemical Journal of medicinal plants,
4(1): 33-46.

- Kovacevic, N., 2004. Basis of Pharmacognosy. 3rd ed. Belgrade, Serbian School Book, 409p.

- Kumar, N. and Goel, N., 2019. Phenolic acids: Natural versatile molecules with promising therapeutic applications. Biotechnology Reports, 24: e00370.

- Liu, Z.H., Wang, W.M., Zhang, Z., Sun, L. and Wu, S.C., 2022. Natural antibacterial and antivirulence alkaloids from Macleaya cordata against methicillin-resistant Staphylococcus aureus. Frontiers in pharmacology, 13: 813172-813172.

- Loi, M. and Paciolla, C., 2021. Plant Antioxidants for Food Safety and Quality: Exploring New Trends of Research. Antioxidants, 10(6): 972.

- Maina, S., Ryu, D.H., Bakari, G., Misinzo, G., Nho, C.W. and Kim, H.Y., 2021. Variation in phenolic compounds and antioxidant activity of various organs of African Cabbage (Cleome gynandra L.) accessions at different growth stages. Antioxidants, 10(12): 1952.

- Matkowski, A., 2008. Plant in vitro culture for the production of antioxidants. A Review. Biotechnology Advances, 26(6): 548-560.

- Mazid, M., Khan, T.A. and Mohammad, F., 2011. Role of secondary metabolites in defense mechanisms of plants. Biology and medicine, 3(2): 232-249.

- Mazza, G., 2007. Anthocyanins and heart health. Annali-Istituto Superiore Di Sanita, 43(4): 369.

- Meda, A., Lamien, C.E., Romito, M., Millogo, J. and Nacoulma, O.G., 2005. Determination of the total phenolic, flavonoid and proline contents in Burkina Fasan honey, as well as their radical scavenging activity. Food Chemistry, 91: 571-577.

- Müller-Riebau, F.J., Berger, B.M., Yegen, O. and Cakir, C., 1997. Seasonal variations in the chemical compositions of essential oils of selected aromatic plants growing wild in Turkey. Journal of Agricultural and Food Chemistry, 45(12):
4821-4825.

- Nabavi, S.J., zali, S.H., Ghorbani, J. and Kazemi, S.Y., 2018. Effects of some ecological factors on extract of Juniperus communis L. in Mountainous Rangelands of Hezarjarib- Behshahr. Journal of Plant Process and Function, 6(19): 367-374.

- Nabavi, S.M., Marchese, A., Izadi, M., Curti, V., Daglia, M. and Nabavi, S.F., 2015. Plants belonging to the genus Thymus as antibacterial agents: From farm to pharmacy. Food Chemistry, 173: 339-347.

- Okoh, O.O., Sadimenko, A.P. and Afolayan, A.J., 2010. Comparative evaluation of the antibacterial activities of the essential oils of Rosmarinus officinalis L. obtained by hydrodistillation and solvent free microwave extraction methods. Food chemistry, 120(1): 308-312.

- Omidbaigi, R., 2009. Production and Processing of Medicinal Plant. Razavi Ghods Astan Publication, Mashhad, 400p.

- Pan, M.H., Lai, C.S. and Ho, C.T., 2010. Anti-inflammatory activity of natural dietary flavonoids. Food & Function, 1(1): 15-31.

- Pareek, A., Suthar, M., Rathore, G.S. and Bansal, V., 2011. Feverfew (Tanacetum parthenium L.): A systematic review. Pharmacognosy reviews,
5(9): 103.

- Paz, J.E.W., Contreras, C.R., Munguía, A.R., Aguilar, C.N. and Inungaray, M.L.C., 2018. Phenolic content and antibacterial activity of extracts of Hamelia patens obtained by different extraction methods. Brazilian journal of microbiology, 49: 656-661.

- Petrussa, E., Braidot, E., Zancani, M., Peresson, C., Bertolini, A., Patui, S. and Vianello, A., 2013. Plant flavonoids biosynthesis, transport and involvement in stress responses. International journal of molecular sciences, 14(7): 14950-14973.

- Peuchant, E., Brun, J., Rigalleau, V., Dubourg, L., Thomas, M. and Daniel, J., 2004. Oxidative and antioxidative status in pregnant women with either gestational or type 1 Diabetes. Clinical Biochemistry, 37: 293-298.

- Pfaffenrath, V., Diener, H.C., Fischer, M., Friede, M. and Henneicke-von Zepelin, H.H., 2002. The efficacy and safety of Tanacetum parthenium (feverfew) in migraine prophylaxis- a double-blind, multicentre, randomized placebo-controlled dose-response study. Cephalalgia, 22(7): 523-532.

- Pourianezhad, F., Tahmasebi, S., Abdusi, V., Nikfar, S. and Mirhoseini, M., 2016. Review on feverfew, a valuable medicinal plant. Journal of HerbMed Pharmacology, 5(2): 45-49.

- Radulovic, N.S., Blagojevic, P.D., Stojanovic-Radic, Z.Z. and Stojanovic, N.M., 2013. Antimicrobial plant metabolites: structural diversity and mechanism of action. Current medicinal chemistry, 20(7): 932-952.

- Ranković, B.R., Kosanić, M.M. and Stanojković, T.P., 2011. Antioxidant, antimicrobial and anticancer activity of the lichens Cladonia furcata, Lecanora atra and Lecanora muralis. BMC complementary and alternative medicine, 11(1): 1-8.

- Rasool, M., Malik, A., Alam, M.Z., Afzal, M., Alam, R., Arsalan, H.M., Azam, M., Achakzai, W.M., Saddozai, S., Haque, A. and Alam, Q., 2018. Optimization of antibacterial activity of ethanolic extracts of Eucalyptus tereticornis and Nigella sativa: Response surface methodology. Pakistan journal of pharmaceutical sciences, 31(4): 26-39.

- Recinella, L., Chiavaroli, A., di Giacomo, V., Antolini, M.D., Acquaviva, A., Leone, S., Brunetti, L., Menghini, L., Ak, G., Zengin, G. and Di Simone, S.C., 2020. Anti-Inflammatory and neuromodulatory effects induced by Tanacetum parthenium water extract: Results from in silico, in vitro and ex vivo studies. Molecules, 26(1): 22.

- Ribeiro, D.A., de Macêdo, D.G., Boligon, A.A., Menezes, I.R.A., de Almeida Souza, M.M. and da Costa, J.G.M., 2019. Influence of seasonality on the phenolic composition of Secondatia floribunda A. DC (Apocynaceae) during its phenological cycle. Acta Physiologiae Plantarum, 41(12): 1-16.

- Roy, A., 2017. A review on the alkaloids an important therapeutic compound from plants. International Journal of Plant Biotechnology, 3(2): 1-9.

- Sabatini, L., Fraternale, D., Di Giacomo, B., Mari, M., Albertini, M.C., Gordillo, B., Rocchi, M.B.L., Sisti, D., Coppari, S., Semprucci, F. and Guidi, L., 2020. Chemical composition, antioxidant, antimicrobial and anti-inflammatory activity of Prunus spinosa L. fruit ethanol extract. Journal of Functional Foods, 67: 103885.

- Saffaryazdi, A., Ganjeali, A., Farhoosh, R. and Cheniany, M., 2020. Variation in phenolic compounds, α-linolenic acid and linoleic acid contents and antioxidant activity of purslane (Portulaca oleracea L.) during phenological growth stages. Physiology and Molecular Biology of Plants, 26(7): 1519-1529.

- Saharkhiz, M., Sattari, M., Goodarzi, G.H. and Omidbaigi, R., 2008. Assessment of antibacterial properties of Tanacetum parthenium L. essential oil. Iranian Journal of Medicinal and Aromatic Plants Research, 24(1): 47-55.

- Salem, N., Msaada, K., Hammami, M., Limam, F., Vasapollo, G. and Marzouk, B., 2014. Variation in anthocyanin and essential oil composition and their antioxidant potentialities during flower development of Borage (Borago officinalis L.). Plant Biosystems- An International Journal Dealing with all Aspects of Plant Biology, 148(3): 444-459.

- Saxena, M., Saxena, J., Nema, R., Singh, D. and Gupta, A., 2013. Phytochemistry of medicinal plants. Journal of pharmacognosy and phytochemistry, 1(6): 123-135.

- Sellami, I.H., Maamouri, E., Chahed, T., Wannes, W.A., Kchouk, M.E. and Marzouk, B., 2009. Effect of growth stage on the content and composition of the essential oil and phenolic fraction of sweet marjoram (Origanum majorana L.). Industrial Crops and Products, 30(3): 395-402.

- Sen, A. and Batra, A., 2012. Determination of antimicrobial potentialities of different solvent extracts of the medicinal plant: Phyllanthus amarus Schum. and Thonn. International Journal of Green Pharmacy (IJGP), 6(1): 1-10.

- Shahidi, F. and Ambigaipalan, P., 2015. Phenolics and polyphenolics in foods, beverages and spices: Antioxidant activity and health effects- A review. Journal of Functional Foods, 18: 820-897.

- Shamsa, F., Monsef, H., Ghamooshi, R. and Verdian-rizi, M., 2008. Spectrophotometric determination of total alkaloids in some Iranian medicinal plants. The Thai Journal of Pharmaceutical Sciences, 32(1): 17-20.

- Shamsudin, N.F., Ahmed, Q.U., Mahmood, S., Ali Shah, S.A., Khatib, A., Mukhtar, S., Alsharif, M.A., Parveen, H. and Zakaria, Z.A., 2022. Antibacterial effects of flavonoids and their structure-activity relationship study: a comparative interpretation. Molecules, 27(4): 1149.

- Sharifi-Rad, M., 2022. Evaluation of phytochemical, antioxidant, antibacterial and anti-inflammatory properties of Moshgak (Ducrosia anethifolia (DC.) Boiss.) at different phenological stages. Iranian Journal of Medicinal and Aromatic Plants Research, 37(6): 971-988.

- Sharifi-Rad, M., Pohl, P., Epifano, F., Zengin, G., Jaradat, N. and Messaoudi, M., 2022. Teucrium polium (L.): phytochemical screening and biological activities at different phenological stages. Molecules, 27(5): 1561.

- Sood, S., Vyas, D. and Nagar, P.K., 2006. Physiological and biochemical studies during flower development in two rose species. Scientia Horticulturae, 108(4): 390-396.

- Stevenson, D. and Hurst, R., 2007. Polyphenolic phytochemicals-just antioxidants or much more?. Cellular and Molecular Life Sciences, 64(22):
2900-2916.

- Tagousop, C.N., Tamokou, J.D.D., Ekom, S.E., Ngnokam, D. and Voutquenne-Nazabadioko, L., 2018. Antimicrobial activities of flavonoid glycosides from Graptophyllum grandulosum and their mechanism of antibacterial action. BMC complementary and alternative medicine, 18(1): 1-10.

- Tena, N., Martín, J. and Asuero, A.G., 2020. State of the art of anthocyanins: Antioxidant activity, sources, bioavailability, and therapeutic effect in human health. Antioxidants, 9(5): 451.

- Towler, M.J. and Weathers, P.J., 2015. Variations in key artemisinic and other metabolites throughout plant development in Artemisia annua L. for potential therapeutic use. Industrial crops and products, 67: 185-191.

- Tungmunnithum, D., Thongboonyou, A., Pholboon, A. and Yangsabai, A., 2018. Flavonoids and other phenolic compounds from medicinal plants for pharmaceutical and medical aspects: An overview. Medicines, 5(3): 93.

- Vega-Arroy, D.J., Ruiz-Espinosa, H., Luna-Guevara, J.J., Luna-Guevara, M.L., Hernández-Carranza, P., Ávila-Sosa, R. and Ochoa-Velasco, C.E., 2017. Effect of solvents and extraction methods on total anthocyanins, phenolic compounds and antioxidant capacity of Renealmia alpinia (Rottb.) Maas peel. Czech Journal of Food Sciences, 35(5): 456-465.

- Velu, G., Palanichamy, V. and Rajan, A.P., 2018. Phytochemical and pharmacological importance of plant secondary metabolites in modern medicine. In: Roopan, S.M., Madhumitha, G., editors. Bioorganic Phase in Natural Food: An Overview. 1 ed. Springer International Publishing AG, part of Springer Nature Springer, Cham, 135-156.

- Verma, V. and Kasera, P.K., 2007. Variations in secondary metabolites in some arid zone medicinal plants in relation to season and plant growth. Indian Journal of Plant Physiology, 12(2): 203.

- Waller, G.R. and Nowacki, E.K., 1978. The role of alkaloids in plants. 143-181, In: Waller, G. (Ed.), Alkaloid Biology and Metabolism in Plants. Springer, Boston, MA, 294p.

- Yang, L., Wen, K.S., Ruan, X., Zhao, Y.X., Wei, F. and Wang, Q., 2018. Response of plant secondary metabolites to environmental factors. Molecules, 23(4): 762.

- Yazdeli, M.Z., Ghazaei, C., Maraghi, E.T., Bakhshi, A. and Shukohifar, M., 2021. Evaluation of antibacterial synergism of methanolic extract of Dracocephalum kotschyi and Trachyspermum ammi. The Malaysian Journal of Medical Sciences, 28(6): 64-76.

- Yetgin, A., Canlı, K. and Altuner, E.M., 2018. Comparison of antimicrobial activity of Allium sativum cloves from China and Taşköprü, Turkey. Advances in pharmacological sciences, 2018: 9302840.

- Yu, M., Gouvinhas, I., Rocha, J. and Barros, A.I., 2021. Phytochemical and antioxidant analysis of medicinal and food plants towards bioactive food and pharmaceutical resources. Scientific reports, 11(1): 1-14.

- Zandi, K., Teoh, B.T., Sam, S.S., Wong, P.F., Mustafa, M.R. and AbuBakar, S., 2011. Antiviral activity of four types of bioflavonoid against dengue virus type-2. Virology Journal, 8(1): 1-11.

- Zribi, I., Omezzine, F. and Haouala, R., 2014. Variation in phytochemical constituents and allelopathic potential of Nigella sativa with developmental stages. South African Journal of Botany, 94: 255-262.