اخبار و اعلانات

 آمار

تعداد نشریات283
تعداد نشریات سازمان81
تعداد شماره‌ها2,727
تعداد مقالات31,057
تعداد مشاهده مقاله28,419,519
تعداد دریافت فایل اصل مقاله16,277,472
Zahedi, A, Saravy, A, Poorghasemi, M. (1402). Evaluating the Antioxidant Effects of Onion (Allium cepa) on Blood Biochemical Factors and Antioxidants after Consuming Tartrazine in Rats. سامانه مدیریت نشریات علمی, 78(6), 1836-1842. doi: 10.32592/ARI.2023.78.6.1836
A Zahedi; A Saravy; M Poorghasemi. "Evaluating the Antioxidant Effects of Onion (Allium cepa) on Blood Biochemical Factors and Antioxidants after Consuming Tartrazine in Rats". سامانه مدیریت نشریات علمی, 78, 6, 1402, 1836-1842. doi: 10.32592/ARI.2023.78.6.1836
Zahedi, A, Saravy, A, Poorghasemi, M. (1402). 'Evaluating the Antioxidant Effects of Onion (Allium cepa) on Blood Biochemical Factors and Antioxidants after Consuming Tartrazine in Rats', سامانه مدیریت نشریات علمی, 78(6), pp. 1836-1842. doi: 10.32592/ARI.2023.78.6.1836
Zahedi, A, Saravy, A, Poorghasemi, M. Evaluating the Antioxidant Effects of Onion (Allium cepa) on Blood Biochemical Factors and Antioxidants after Consuming Tartrazine in Rats. سامانه مدیریت نشریات علمی, 1402; 78(6): 1836-1842. doi: 10.32592/ARI.2023.78.6.1836

Evaluating the Antioxidant Effects of Onion (Allium cepa) on Blood Biochemical Factors and Antioxidants after Consuming Tartrazine in Rats

Archives of Razi Institute
مقاله 20، دوره 78، شماره 6، بهمن و اسفند 2023، صفحه 1836-1842    اصل مقاله (706.45 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.32592/ARI.2023.78.6.1836
نویسندگان
A Zahedi* 1؛ A Saravy2؛ M Poorghasemi3
1Department of Veterinary Pathology, Faculty of Veterinary Medicine, Islamic Azad University, Rasht Branch, Rasht, Iran
2Department of Internal Medicine, Guilan University of Medical Sciences, Rasht, Iran
3Department of Animal Science, Faculty of Agriculture, Islamic Azad University, Rasht Branch, Rasht, Iran
چکیده
Colors have been adding to food naturally and artificially for centuries to make them attractive. According to the Food and Drug Organization, eight artificial colors were registered for the nutrition application, one of them is tartrazine, which is widely used in foods and cosmetics. Food colors cause a significant decrease in weight, an increase in proteins and liver enzymes, an increase in thyroid hormones, an increase in total cholesterol and triglyceride. Onion as an antioxidant can reduce the harmful effects of artificial food colors on weight gain, antioxidant activity and blood biochemical factors. This study aims to investigate the antioxidant properties of the onion on serum biochemical factors and antioxidants in Wistar rats after consuming tartrazine. Eighty Rats were divided into four groups,20 mice in each. The first group received water without additives and was considered to be the control, the second group received tartrazine, the third group received tartrazine with onion juice, and the fourth group received only onion juice through gastric gavage. This experiment was performed for 60 days, and then the antioxidant activities of SOD, CAT, GPX, and the biochemical parameters of HDL and LDL were measured. Tartrazine decreased the antioxidant activities of SOD, CAT, GPX, and the biochemical parameters of HDL and LDL. The results showed that the consumption of tartrazine causes the production of free radicals, which is the reason for the significant reduction of antioxidant activities and serum biochemical factors. Onion as an antioxidant in this study reduces the effects of tartrazine on antioxidant activities and serum biochemical factors.
کلیدواژه‌ها
Allium cepa؛ Antioxidant؛ Blood factors؛ Rat؛ Tartrazine
مراجع
References
1. Sasaki YF, Kawaguchi S, Kamaya AM. The comet
assay with 8 mouse organs: Results with 39 currently
used food additives. Mutat Res. 2002;519:103-119.
2. Coskun O, Kanter M, Korkmaz A, Oter S. Quercetin, a
flavonoid antioxidant, prevents and protects
streptozotocin-induced oxidative stress and beta-cell
damage in rat pancreas. Pharmacol Res.
2005;51(2):117-123.
3. Sharma RK, Agarwal A. Role of reactive oxygen
species in male infertility. J Urol. 1996;48:835-850.
4. Khaki A, Fathiazad F, Nouri M, Khaki AA, Khamenehi
HJ, Hamadeh M. Evaluation of androgenic activity of
allium cepa on spermatogenesis in the rat. Folia
Morphol. 2009;68(1):45-51.
5. Thomas MJ. The role of free radicals antioxidants. Nutr.
2000;16(7):716-727.
6. Rowe KS, Rowe KJ. Synthetic food coloring and
behavior: a dose response effect in a double-blind,
placebo-controlled, repeated-measures study. J Pediatr.
1994;125(5):691-698.
7. Velioglu YS, Mazza G, Gao L, Oomah BD. Antioxidant
activity and total phenolics in selected fruits, vegetables
and grain products. J Agric Food Chem.
1998;46(10):113-117.
8. Himri I, Bellachen S, Souna F, Belmekki F, Aziz M,
Bnouham M, Aziz K. A 90-day oral toxicity study of
tartrazine, a synthetic food dye, in wistar rats. Int J
Pharm Pharm. Sci. 2011;3(3):159-69.
9. Gautam D, Sharma G, Goyal RP. Evaluation of toxic
impact of tartrazine on male Swiss Albino Mice.
Pharmacol. 2010;1:133-140.
10. Khasanah H, Fanata WID, Kusbianto DE. Analysis of
chicken gut microbiome fed by Phyllanthus urinaria as
phytobiotic using 16S rRNA metagenome. Iranian J
Appl Anim Sci. 2022;12(1):151-160.
11.Boots AW, Haenen GRMM, Bast A. Health effects of
quercetin: from antioxidant to nutraceutical. European J
Pharmacol. 2008;585:337-325.
12. Nikbakht SA, Mohammadabadi T, Mirzadeh K. The
effect of feeding Tribulus terrestris plant powder on
growth performance, digestibility, rumen and blood
parameters of Iranian Arabic lambs. Iranian J Appl
Anim Sci. 2021;11(4):781-788.
13. Hossein Abadi M, Ghoorchi T, Amirteymouri E,
Poorghasemi M. The effect of different processing
methods of linseed on growth performance, nutrient
digestibility, blood parameters and ruminate behavior of
lambs. Vet Med Sci. 2023;2023:1-10.
14. Kikelomo OM, Stephen MS, Michael AF, Udoka EO,
Toyin YF. Protective roles of onion and garlic extracts
on cadmium-induced changes in sperm characteristics
and testicular oxidative damage in rats. Food Chem
Toxicol. 2008;46(12):604-611.
15.Calomme M, Pieters L, Vlietinck A, Vanden Berghe D.
Inhibition of bacterial mutagenesis by citrus flavonoids.
Planta Med. 1996;62(3):222-226.
16. Park J, Kim J, Kim MK. Onion flesh and onion peel
enhance antioxidant status in aged rats. J Nutr Sci
Vitaminol. 2007;53(1):21-29.
17. Sharma G, Gautam D, Goyal RP. Tartrazine induced
haematological and serological changes in female swiss
albino mice, Musmusculus. Pharmacol. 2009;3:774-788

آمار
تعداد مشاهده مقاله: 14,189
تعداد دریافت فایل اصل مقاله: 155


counter
سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب