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Zahedi, Afshin, Poorghasemi, mohammadreza, Saravy, Shayan. (1402). Evaluating the Antioxidant Effects of Onion (Allium cepa) on Blood Biochemical Factors and Antioxidants After Consuming Tartrazine in Rats. سامانه مدیریت نشریات علمی, (), -. doi: 10.22092/ari.2023.362591.2758
Afshin Zahedi; mohammadreza Poorghasemi; Shayan Saravy. "Evaluating the Antioxidant Effects of Onion (Allium cepa) on Blood Biochemical Factors and Antioxidants After Consuming Tartrazine in Rats". سامانه مدیریت نشریات علمی, , , 1402, -. doi: 10.22092/ari.2023.362591.2758
Zahedi, Afshin, Poorghasemi, mohammadreza, Saravy, Shayan. (1402). 'Evaluating the Antioxidant Effects of Onion (Allium cepa) on Blood Biochemical Factors and Antioxidants After Consuming Tartrazine in Rats', سامانه مدیریت نشریات علمی, (), pp. -. doi: 10.22092/ari.2023.362591.2758
Zahedi, Afshin, Poorghasemi, mohammadreza, Saravy, Shayan. Evaluating the Antioxidant Effects of Onion (Allium cepa) on Blood Biochemical Factors and Antioxidants After Consuming Tartrazine in Rats. سامانه مدیریت نشریات علمی, 1402; (): -. doi: 10.22092/ari.2023.362591.2758

Evaluating the Antioxidant Effects of Onion (Allium cepa) on Blood Biochemical Factors and Antioxidants After Consuming Tartrazine in Rats

Archives of Razi Institute
مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 20 تیر 1402
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2023.362591.2758
نویسندگان
Afshin Zahedi* 1؛ mohammadreza Poorghasemi2؛ Shayan Saravy3
1Department of Veterinary Pathology, Faculty of Veterinary Medicine, Islamic Azad University, Rasht, Iran
2Department of Animal Science, Science and Research Branch, Islamic Azad University, Tehran, Iran
3Department of Internal Medicine, Guilan University of Medical Sciences, Rasht, Iran
چکیده
Colors have been adding to food naturally and artificially for centuries to make them attractive. According to the Food and Drug Organization, eight artificial colors were registered for the nutrition application, one of them is tartrazine, which is widely used in foods and cosmetics. Food colors cause a significant decrease in weight, an increase in proteins and liver enzymes, an increase in thyroid hormones, an increase in total cholesterol and triglyceride. Onion as an antioxidant can reduce the harmful effects of artificial food colors on weight gain, antioxidant activity and blood biochemical factors. This study aims to investigate the antioxidant properties of the onion on serum biochemical factors and antioxidants in Wistar rats after consuming tartrazine. Eighty Rats were divided into four groups,20 mice in each. The first group received water without additives and was considered to be the control, the second group received tartrazine, the third group received tartrazine with onion juice, and the fourth group received only onion juice through gastric gavage. This experiment was performed for 60 days, and then the antioxidant activities of SOD, CAT, GPX, and the biochemical parameters of HDL and LDL were measured. Tartrazine decreased the antioxidant activities of SOD, CAT, GPX, and the biochemical parameters of HDL and LDL. The results showed that the consumption of tartrazine causes the production of free radicals, which is the reason for the significant reduction of antioxidant activities and serum biochemical factors. Onion as an antioxidant in this study reduces the effects of tartrazine on antioxidant activities and serum biochemical factors.
کلیدواژه‌ها
Allium cepa؛ Antioxidant؛ Tartrazine؛ Rat؛ Blood factors
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تعداد مشاهده مقاله: 13


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