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Al-Ani, F. W, Fahad, H. M. (1402). Detection of the Level of Interleukin-8 in the Serum of Burn Patients by ELISA Technique. سامانه مدیریت نشریات علمی, 78(3), 1087-1093. doi: 10.22092/ari.2022.359993.2529
F. W Al-Ani; H. M Fahad. "Detection of the Level of Interleukin-8 in the Serum of Burn Patients by ELISA Technique". سامانه مدیریت نشریات علمی, 78, 3, 1402, 1087-1093. doi: 10.22092/ari.2022.359993.2529
Al-Ani, F. W, Fahad, H. M. (1402). 'Detection of the Level of Interleukin-8 in the Serum of Burn Patients by ELISA Technique', سامانه مدیریت نشریات علمی, 78(3), pp. 1087-1093. doi: 10.22092/ari.2022.359993.2529
Al-Ani, F. W, Fahad, H. M. Detection of the Level of Interleukin-8 in the Serum of Burn Patients by ELISA Technique. سامانه مدیریت نشریات علمی, 1402; 78(3): 1087-1093. doi: 10.22092/ari.2022.359993.2529

Detection of the Level of Interleukin-8 in the Serum of Burn Patients by ELISA Technique

Archives of Razi Institute
مقاله 39، دوره 78، شماره 3، مرداد و شهریور 2023، صفحه 1087-1093    اصل مقاله (486.34 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2022.359993.2529
نویسندگان
F. W Al-Ani* 1؛ H. M Fahad2
1Specialized Burns Hospital, Medical City, Baghdad, Iraq
2College of Medicine, AL-Iraqia University, Baghdad, Iraq
چکیده
Burn injuries are the most frequent injuries in the world, with a death rate of 2.3-3.6%. Children and people of working age constitute 85-90% of the burn cases. Burn injury results in metabolic problems, a generalized inflammatory response, inefficient energy use, and other physiological alternations that may cause organ and system dysfunction and sepsis. Sepsis is mostly caused by multiple organ failures and has unique characteristics in burn injuries, which make it the most dangerous complication of burn injuries. This study aimed to investigate the correlation between sepsis in burn patients and the level of interleukin 8 (IL-8) in their serum. In total, 60 patients with burn injuries were included in this study. Blood samples were obtained from 60 burn patients and 30 healthy individuals as controls. The BacT/Alert and Vitek2 systems were used to identify the bacteria and determine their susceptibility to these bacteria. Moreover, enzyme-linked immunosorbent assay (ELISA) was used to determine IL-8 serum levels. Based on the results, elevated levels of IL-8 were observed in the serum of burn patients, compared to healthy individuals. Concentration of IL-8 was significantly higher in patients with sepsis, compared to healthy individuals without sepsis.
کلیدواژه‌ها
Detection؛ Interleukin-8؛ Serum of Burn Patients؛ ELISA Technique
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مراجع
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