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Salim Abd Al-Hussein, S, Ibrahim Al Dirawi, A. A, Majeed Naeem Al-Khalifah, R. (1402). Assessment of Hydroxyproline Content in Rabbit Achilles Tendon Treated with Platelet Rich Fibrin (PRF). سامانه مدیریت نشریات علمی, 78(3), 943-948. doi: 10.22092/ari.2022.359891.2501
S Salim Abd Al-Hussein; A. A Ibrahim Al Dirawi; R Majeed Naeem Al-Khalifah. "Assessment of Hydroxyproline Content in Rabbit Achilles Tendon Treated with Platelet Rich Fibrin (PRF)". سامانه مدیریت نشریات علمی, 78, 3, 1402, 943-948. doi: 10.22092/ari.2022.359891.2501
Salim Abd Al-Hussein, S, Ibrahim Al Dirawi, A. A, Majeed Naeem Al-Khalifah, R. (1402). 'Assessment of Hydroxyproline Content in Rabbit Achilles Tendon Treated with Platelet Rich Fibrin (PRF)', سامانه مدیریت نشریات علمی, 78(3), pp. 943-948. doi: 10.22092/ari.2022.359891.2501
Salim Abd Al-Hussein, S, Ibrahim Al Dirawi, A. A, Majeed Naeem Al-Khalifah, R. Assessment of Hydroxyproline Content in Rabbit Achilles Tendon Treated with Platelet Rich Fibrin (PRF). سامانه مدیریت نشریات علمی, 1402; 78(3): 943-948. doi: 10.22092/ari.2022.359891.2501

Assessment of Hydroxyproline Content in Rabbit Achilles Tendon Treated with Platelet Rich Fibrin (PRF)

Archives of Razi Institute
مقاله 20، دوره 78، شماره 3، مرداد و شهریور 2023، صفحه 943-948    اصل مقاله (605.24 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2022.359891.2501
نویسندگان
S Salim Abd Al-Hussein* ؛ A. A Ibrahim Al Dirawi؛ R Majeed Naeem Al-Khalifah
Department of Veterinary Surgery and Obstetric, University of Basra, Basra, Iraq
چکیده
Tendon is similar to rope and consists of strong, flexible, dense connective tissue. Tendon disorder healing is challenging as it is an avascular tissue. The repaired tissue appears scar-like, and its biomechanical properties never ultimately return to their pre-injury state. This study aimed to evaluate the effects of platelet-rich fibrin (PRF) on the hydroxyproline content of the Achilles tendon after injury. For this purpose, 24 adult rabbits weighing 1.5-2 kg were used in this study. The animals were divided into three groups of eight, including the advanced-PRF (A-PRF) group in which the tendon defect was treated with xenogeneic A-PRF, the leukocyte-PRF (L-PRF) group in which xenogeneic L-PRF was used for tendon defect treatment, and a control group which was treated with normal saline. Hydroxyproline concentration was measured 1 and 2 months after the operation. Clinically, lameness was improved in the A-PRF group, compared to the L-PRF and control groups at the end of the third week after the surgery. Hydroxyproline level was significantly increased in the A-PRF group (50.33±1.44), compared to the L-PRF (44.70±1.12) and control (35.97±1.05) groups 2 months after the surgery (P<0.05). Moreover, the L-PRF group showed an increase in hydroxyproline content, compared to the control at the same period. The results of the current study demonstrated that A-PRF could enhance the hydroxyproline content of rabbit Achilles tendon after injury. Xenogenic PRF can be used as an alternative biomaterial to accelerate and regenerate tendon tissue.
کلیدواژه‌ها
Hydroxyproline؛ PRF؛ Rabbit Achilles tendon؛ Tendon healing
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مراجع
  1. Docheva D, Müller SA, Majewski M, Evans CH. Biologics for tendon repair. Adv Drug Deliv Rev. 2015;84:222-39.
  2. Federer AE, Steele JR, Dekker TJ, Liles JL, Adams SB. Tendonitis and tendinopathy: what are they and how do they evolve? Foot Ankle Clin. 2017;22(4):665-76.
  3. Zhang J, Wang JH. Characterization of differential properties of rabbit tendon stem cells and tenocytes. BMC Musculoskelet Disord. 2010;11(1):1-11.
  4. Bigham-Sadegh A, Ghasemi S, Karimi I, Mirshokraei P, Nazari H, Oryan A. Tendon healing with allogenic fibroblast and static magnetic field in rabbit model. Iran J Vet Surg. 2015;10(2):11-9.
  5. Wu F, Nerlich M, Docheva D. Tendon injuries: Basic science and new repair proposals. EFORT Open Rev. 2017;2(7):332-42.
  6. Ehrenfest DMD, Andia I, Zumstein MA, Zhang C-Q, Pinto NR, Bielecki T. Classification of platelet concentrates (Platelet-Rich Plasma-PRP, Platelet-Rich Fibrin-PRF) for topical and infiltrative use in orthopedic and sports medicine: current consensus, clinical implications and perspectives. Muscles Ligaments Tendons J. 2014;4(1):3.
  7. Zhou S, Sun C, Huang S, Wu X, Zhao Y, Pan C, et al. Efficacy of adjunctive bioactive materials in the treatment of periodontal intrabony defects: a systematic review and meta-analysis. BioMed Res Int. 2018;2018.
  8. Pradeep A, Bajaj P, Rao NS, Agarwal E, Naik SB. Platelet‐rich fibrin combined with a porous hydroxyapatite graft for the treatment of 3‐wall intrabony defects in chronic periodontitis: a randomized controlled clinical trial. J Periodontol. 2017;88(12):1288-96.
  9. Gong F, Cui L, Zhang X, Zhan X, Gong X, Wen Y. Piperine ameliorates collagenase-induced Achilles tendon injury in the rat. Connect Tissue Res. 2018;59(1):21-9.
  1. Elfeky MG, Mantawy EM, Gad AM, Fawzy HM, El-Demerdash E. Mechanistic aspects of antifibrotic effects of honokiol in Con A-induced liver fibrosis in rats: Emphasis on TGF-β/SMAD/MAPK signaling pathways. Life Sci. 2020;240:117096.
  2. Liu R, Zhao Z, Zou L, Fang Q, Chen L, Argento A, et al. Compact, non-invasive frequency domain lifetime differentiation of collagens and elastin. Sens. Actuators B Chem. 2015;219:283-93.
  3. Sohn J, Couto M. Chapter 8: Anatomy. Physiology, and Behavior In: The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents, 1st ed MA Suckow, KA Stevens, and RP Wilson (eds) Academic Press (Elsevier), Amsterdam. 2012:195-217.
  4. Ghanaati S, Booms P, Orlowska A, Kubesch A, Lorenz J, Rutkowski J, et al. Advanced platelet-rich fibrin: a new concept for cell-based tissue engineering by means of inflammatory cells. J Oral Implantol. 2014;40(6):679-89.
  5. Fujioka‐Kobayashi M, Miron RJ, Hernandez M, Kandalam U, Zhang Y, Choukroun J. Optimized platelet‐rich fibrin with the low‐speed concept: growth factor release, biocompatibility, and cellular response. J Periodontol. 2017;88(1):112-21.
  6. Wanstrath AW, Hettlich BF, Su L, Smith A, Zekas LJ, Allen MJ, et al. Evaluation of a single intra‐articular injection of autologous protein solution for treatment of osteoarthritis in a canine population. Vet Surg. 2016;45(6):764-74.
  7. Geburek F, Gaus M, van Schie H, Rohn K, Stadler PM. Effect of intralesional platelet-rich plasma (PRP) treatment on clinical and ultrasonographic parameters in equine naturally occurring superficial digital flexor tendinopathies–a randomized prospective controlled clinical trial. BMC Vet Res. 2016;12(1):1-16.
  8. Longo UG, Ronga M, Maffulli N. Achilles tendinopathy. Sports Med Arthrosc Rev. 2018;26(1):16-30.
  9. Alkhalifa RNM, Sharifi D, Bokaie S, Bashiri A, Shad H, Esanejad R, et al. Evaluation of the Hydroxyproline Content in the Frozen Allograft Tendon Impregnated With the Mesenchymal Cells & PRP in Lamb. Iran J Vet Med. 2019;13(1):1-9.
  10. Moghaddam AJ, Kazemi D. Evaluating the Feasibility of Esophagotomy Suture Line Reinforcement Using Platelet Rich Fibrin Membrane and Its Effect on Wound Healing. Iran J Vet Surg. 2016;11:9-15.
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