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Abdullateef Abdullah, Z, Fouad Ali, L. (1402). Role of Serum Ferritin, D-Dimer, and C-Reactive Protein Parameters in COVID 19 Severity. سامانه مدیریت نشریات علمی, 78(2), 737-742. doi: 10.22092/ari.2022.359731.2466
Z Abdullateef Abdullah; L Fouad Ali. "Role of Serum Ferritin, D-Dimer, and C-Reactive Protein Parameters in COVID 19 Severity". سامانه مدیریت نشریات علمی, 78, 2, 1402, 737-742. doi: 10.22092/ari.2022.359731.2466
Abdullateef Abdullah, Z, Fouad Ali, L. (1402). 'Role of Serum Ferritin, D-Dimer, and C-Reactive Protein Parameters in COVID 19 Severity', سامانه مدیریت نشریات علمی, 78(2), pp. 737-742. doi: 10.22092/ari.2022.359731.2466
Abdullateef Abdullah, Z, Fouad Ali, L. Role of Serum Ferritin, D-Dimer, and C-Reactive Protein Parameters in COVID 19 Severity. سامانه مدیریت نشریات علمی, 1402; 78(2): 737-742. doi: 10.22092/ari.2022.359731.2466

Role of Serum Ferritin, D-Dimer, and C-Reactive Protein Parameters in COVID 19 Severity

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مقاله 30، دوره 78، شماره 2، خرداد و تیر 2023، صفحه 737-742    اصل مقاله (367.41 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2022.359731.2466
نویسندگان
Z Abdullateef Abdullah؛ L Fouad Ali*
Department of Biology, College of Science, University of Baghdad, Baghdad, Iraq
چکیده
Following the epidemics caused by the transmission of the common virus between humans and animals (COVID-19), coronavirus 2 (SARS-CoV-2) is the third and most deadly strain of RNA virus that can cause respiratory, digestive, and nervous system problems, and there are many unknown complications. This study included 170 clinical samples of nasopharyngeal swaps (100 patients and 70 controls for both males and females). RT-PCR was performed, and blood samples were taken for biochemical analyses. They were obtained from Iraqi patients aged 25 to 92 years old. Between November 2021 and March 2022, COVID-19 patients were admitted to Dar al-salam Hospital, Alyarmok Teaching Hospital, and Alshefaa Hospital. AFIAS D-Dimer, AFIAS ferritin, and NycoCard CRP tests were performed on the patients and were classified depending on the severity of their infection (mild or moderate, severe and critical). The results showed a significant increase in ferritin in critically ill patients (545.58 ± 57.71). A significant increase of D-dimer was found with different severity with highly significant in the critical group (3.93 ± 0.79). With varying degrees of severity, a substantial rise in CRP was discovered with highly significant in the critical group (96.27 ± 14.55) between the severity group (p-value <0.001). Also, COVID-19 individuals in the age range (50 – 60) tended to be more severe than younger people, whereas the effect of gender is not significant in any patient group. The biochemical factors, including D-Dimer, ferritin, and CRP, are effective in the disease's occurrence of symptoms and severity.
کلیدواژه‌ها
Biochemical parameters؛ COVID-19؛ RT-PCR؛ SARS-CoV-2؛ Serum ferritin؛ D-dimer؛ C-reactive protein
اصل مقاله
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