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Othman Jassim, H, Al-Ghaban, N. M. H. (1402). Effect of Eucommia Ulmoides on Healing of Bon Defect Using Histological and Histomorphometric Analysis in Rat: in vivo Study. سامانه مدیریت نشریات علمی, 78(2), 651-657. doi: 10.22092/ari.2022.359483.2434
H Othman Jassim; N. M. H Al-Ghaban. "Effect of Eucommia Ulmoides on Healing of Bon Defect Using Histological and Histomorphometric Analysis in Rat: in vivo Study". سامانه مدیریت نشریات علمی, 78, 2, 1402, 651-657. doi: 10.22092/ari.2022.359483.2434
Othman Jassim, H, Al-Ghaban, N. M. H. (1402). 'Effect of Eucommia Ulmoides on Healing of Bon Defect Using Histological and Histomorphometric Analysis in Rat: in vivo Study', سامانه مدیریت نشریات علمی, 78(2), pp. 651-657. doi: 10.22092/ari.2022.359483.2434
Othman Jassim, H, Al-Ghaban, N. M. H. Effect of Eucommia Ulmoides on Healing of Bon Defect Using Histological and Histomorphometric Analysis in Rat: in vivo Study. سامانه مدیریت نشریات علمی, 1402; 78(2): 651-657. doi: 10.22092/ari.2022.359483.2434

Effect of Eucommia Ulmoides on Healing of Bon Defect Using Histological and Histomorphometric Analysis in Rat: in vivo Study

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مقاله 19، دوره 78، شماره 2، خرداد و تیر 2023، صفحه 651-657    اصل مقاله (643.18 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2022.359483.2434
نویسندگان
H Othman Jassim* ؛ N. M. H Al-Ghaban
Oral Diagnosis Department, Collage of Dentistry, University of Baghdad, Baghdad, Iraq
چکیده
Bone repair is a complex multistep process. The flavonoid group present in Eucommia ulmoides (EU) helps to increase bone mineral density. This study aimed to evaluate the healing process of bone defects treated with EU and compare it to the control group using histological and histomorphometric tests. For this purpose, 24 albino rats were anesthetized and both of their femurs were prepared by drilling intra-bony defects (2 mm in diameter and 3 mm in depth). In each rat, the right bony defects were considered control, while the left bony defects were treated with EU. Moreover, scarification was done with 1-, 2-, and 4-week healing intervals (n=8). Histological and histomorphometric analysis of bone microarchitectures were performed for more evaluations and the bone cells were counted (osteoblast, osteocyte, and osteoclast) for comparison with the normal percentages. Moreover, trabecular number, trabecular area, and bone marrow area per mm2 were measured using the ImageJ software. The recorded histological data revealed the acceleration of bone healing in the EU group, compared to the control group. Highly significant differences were observed in the animals treated with EU, compared to the control group for almost all histomorphometric parameters investigated in this Study. In conclusion, EU can improve bone healing and increase osteogenic capacity in rats.
کلیدواژه‌ها
Bone healing؛ Eucommia Ulmoides؛ ImageJ
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مراجع
  1. Oryan A, Alidadi S, Moshiri A. Current concerns regarding healing of bone defects. Hard Tissue. 2013;2(2):1-12.
  2. Marsell R, Einhorn TA. The biology of fracture healing. Injury. 2011;42(6):551-5.
  3. Hussain T, Tan B, Liu G, Oladele OA, Rahu N, Tossou MC, et al. Health-Promoting Properties of Eucommia ulmoides: A Review. Evid Based Complement Alternat Med. 2016;2016:5202908.
  4. Chen X, Sang X, Li S, Zhang S, Bai L. Studies on a chlorogenic acid-producing endophytic fungi isolated from Eucommia ulmoides Oliver. J Ind Microbiol Biotechnol. 2010;37(5):447-54.
  5. Huiming H, Hongquan Y, Baoqiang L, Yuehu P. Study on the constituents of the bark of Eucommia ulmoides. Mol Plant Breed. 2003;1(5/6):801-3.
  6. Hong YK, Liu WJ, Li T, She SY. Optimization of extraction of Eucommia ulmoides polysaccharides by response surface methodology. Carbohydr Polym. 2013;92(2):1761-6.
  7. Tomoda M, Shimizu N, Kanari M. A reticuloendothelial system-activating glycan from the barks of Eucommia ulmoides. Phytochemistry. 1990;29(10):3091-4.
  8. Zhang R, Liu ZG, Li C, Hu SJ, Liu L, Wang JP, et al. Du-Zhong (Eucommia ulmoides Oliv.) cortex extract prevent OVX-induced osteoporosis in rats. Bone. 2009;45(3):553-9.
  9. Hendra R, Ahmad S, Oskoueian E, Sukari A, Shukor MY. Antioxidant, anti-inflammatory and cytotoxicity of Phaleria macrocarpa (Boerl.) Scheff fruit. BMC Complement Altern Med. 2011;11:1-10.
  1. Zhang L, Ravipati AS, Koyyalamudi SR, Jeong SC, Reddy N, Bartlett J, et al. Anti-fungal and anti-bacterial activities of ethanol extracts of selected traditional Chinese medicinal herbs. Asian Pac J Trop Med. 2013;6(9):673-81.
  2. Liang H, Yu F, Liu X, Yuan B, Zhao Z, Wu S. Effect of Eucommia ulmoides extract on osteoblast proliferation. Trop J Pharm Res. 2017;16(11):2675-9.
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