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Ali Abd, S, Alsaffar, J. M. J, Agop, A. K, Kadhem, E. J. (1401). Comparison of Skin Bacteria between Psoriasis Patients and Healthy Control. سامانه مدیریت نشریات علمی, 77(5), 1737-1740. doi: 10.22092/ari.2022.359398.2414
S Ali Abd; J. M. J Alsaffar; A. K Agop; E. J Kadhem. "Comparison of Skin Bacteria between Psoriasis Patients and Healthy Control". سامانه مدیریت نشریات علمی, 77, 5, 1401, 1737-1740. doi: 10.22092/ari.2022.359398.2414
Ali Abd, S, Alsaffar, J. M. J, Agop, A. K, Kadhem, E. J. (1401). 'Comparison of Skin Bacteria between Psoriasis Patients and Healthy Control', سامانه مدیریت نشریات علمی, 77(5), pp. 1737-1740. doi: 10.22092/ari.2022.359398.2414
Ali Abd, S, Alsaffar, J. M. J, Agop, A. K, Kadhem, E. J. Comparison of Skin Bacteria between Psoriasis Patients and Healthy Control. سامانه مدیریت نشریات علمی, 1401; 77(5): 1737-1740. doi: 10.22092/ari.2022.359398.2414

Comparison of Skin Bacteria between Psoriasis Patients and Healthy Control

Archives of Razi Institute
مقاله 28، دوره 77، شماره 5، آذر و دی 2022، صفحه 1737-1740    اصل مقاله (373.83 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2022.359398.2414
نویسندگان
S Ali Abd* 1؛ J. M. J Alsaffar1؛ A. K Agop1؛ E. J Kadhem2
1Biotechnology Department, College of Science, University of Baghdad, Baghdad, Iraq
2Ministry of Industry, Ibn Sina Research Center, Baghdad, Iraq
چکیده
Psoriasis is an autoimmune, persistent, inflammatory skin illness that is influenced by a variety of circumstances. Psoriasis etiology is strongly linked to bacteria, particularly those in the pharynx and skin. This research intended to deepen our understanding by elucidating the connection between the skin microbiome and psoriasis to improve therapeutic balance using probiotics, antimicrobials, and even topical microbiota transplantation. In this work, the culture-dependent approach is utilized to compare the skin microbiomes of psoriatic and healthy individuals. On brane-heart infusion agar, swabs from 60 psoriasis patients in the flare-up stag and 40 healthy controls were cultured and grown for 48 hours. The resultant colonies were then subcultured and purified to produce a single pure colony. Using Macconkey agar for preliminary colony identification, Vitek then characterized the purified colonies. The results revealed substantial bacterial species and phyla variations between psoriatic patients and healthy controls. In addition, increased rates of opportunistic infections Pseudomonas stutzeri and Staphylococcus pseudintermedius were detected in psoriatic patients' normal skin and lesions.
کلیدواژه‌ها
Psoriasis؛ Skin Microbiome؛ Dysbiosis
مراجع
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