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Falih Soliman, N, Jasim Mohamad, B. (1401). Clinical and Histopathological Characteristics of Colorectal Cancer in Iraq between 2015-2021. سامانه مدیریت نشریات علمی, 77(6), 2407-2413. doi: 10.22092/ari.2022.358613.2263
N Falih Soliman; B Jasim Mohamad. "Clinical and Histopathological Characteristics of Colorectal Cancer in Iraq between 2015-2021". سامانه مدیریت نشریات علمی, 77, 6, 1401, 2407-2413. doi: 10.22092/ari.2022.358613.2263
Falih Soliman, N, Jasim Mohamad, B. (1401). 'Clinical and Histopathological Characteristics of Colorectal Cancer in Iraq between 2015-2021', سامانه مدیریت نشریات علمی, 77(6), pp. 2407-2413. doi: 10.22092/ari.2022.358613.2263
Falih Soliman, N, Jasim Mohamad, B. Clinical and Histopathological Characteristics of Colorectal Cancer in Iraq between 2015-2021. سامانه مدیریت نشریات علمی, 1401; 77(6): 2407-2413. doi: 10.22092/ari.2022.358613.2263

Clinical and Histopathological Characteristics of Colorectal Cancer in Iraq between 2015-2021

Archives of Razi Institute
مقاله 48، دوره 77، شماره 6، بهمن و اسفند 2022، صفحه 2407-2413    اصل مقاله (474.71 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2022.358613.2263
نویسندگان
N Falih Soliman* ؛ B Jasim Mohamad
Department of Biology, Collage of Science, University of Baghdad, Baghdad, Iraq
چکیده
Colorectal cancer (C.R.C.) is the commonest malignancy in the gastrointestinal tract and is the fourth leading reason behind cancer-associated death in the world. It usually begins with the non-cancerous proliferation of mucosal epithelial cells. These growths are polyps and might grow gradually for 10–20 years before becoming cancerous. This study was designed to investigate the epidemiology of the diagnosed cases of colorectal cancer from 2015 to 2021 in Baghdad. A total of 60 cases of different colorectal cancer samples were collected from Medical City Teaching Hospital, Baghdad, and private labs. Clinical information was also collected, including patients' age, tumor size, gender and location, pathological grade, and stage. Results revealed a high incidence of C.R.C. in patients aged 60-90 years for the rate of 40.3%, with a high frequency in the left colon of 59.6%. The dominant tumor size was 5cm in malignant cases, and a high incidence of C.R.C. was seen in the female by 52.0%. While the most frequent tumor stage was stage I.I.A., with a rate of 59.6%, and moderately differentiated was the foremost one with 67.3% (P≤0.05). The most common type of C.R.C. in Iraq is adenocarcinoma, which occurs in patients older than 60years and presented at the I.I.A. stage of disease with moderate tumor grade. Early disease detection and diagnosis are effective in its control and treatment.
کلیدواژه‌ها
Colorectal Tumors؛ Adenocarcinoma؛ Risk Factors؛ Epidemiology
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مراجع
  1. Sulaiman MM, Salih KN. Levels of Interleukin-6 in Colorectal Carcinoma Patients in Relation to Metastasis degree. Med J Tikrit Univ. 2019;25(2).
  2. Rawla P, Sunkara T, Barsouk A. Epidemiology of colorectal cancer: incidence, mortality, survival, and risk factors. Prz Gastroenterol. 2019;14(2):89-103.
  3. Li C, Zheng H, Jia H, Huang D, Gu W, Cai S, et al. Prognosis of three histological subtypes of colorectal adenocarcinoma: A retrospective analysis of 8005 Chinese patients. Cancer Med. 2019;8(7):3411-9.
  4. Abdulhussain SS, Othman OH. Epidemiological study of colorectal and anal cancer in Kirkuk City. Iraqi J Med Sci. 2014;1:33-46.
  5. Altoriah KMJ, Jumaah AAS, Abdulhussein AA, Aljanabi AAH, Al-Haddad HS, Al-Quzweni A, et al. Immunohistochemical Study of Adenomatous Polyposis Coli Protein in Colorectal Carcinoma and its Precursor Lesions in Iraq. Age. 2020;21(30):31-40.
  1. Hama HA, Karim AY. Evaluation of p53 expression among Colorectal Cancer patients. Zanco Journal of Pure Applied Sciences. 2019;31(6):130-4.
  2. Fadaka AO, Pretorius A, Klein A. Biomarkers for Stratification in Colorectal Cancer: MicroRNAs. Cancer Control. 2019;26(1):1073274819862784.
  3. Munoz-Maldonado C, Zimmer Y, Medova M. A Comparative Analysis of Individual RAS Mutations in Cancer Biology. Front Oncol. 2019;9:1088.
  4. Al-Saadi HA. Research Article Role Of Il10, Tnf In Iraqi Patients With Colon Cancer. Chemotherapy. 2014;38(7):0.5.
  5. Alshewered AS, Al-Naqqash Ma. Rectal cancer and chemoradiation in Iraq: systematic review and meta-analysis. J Coloproctology. 2019;39(04):309-18.
  6. Ayroldi E, Cannarile L, Adorisio S, Delfino DV, Riccardi C. Role of Endogenous Glucocorticoids in Cancer in the Elderly. Int J Mol Sci. 2018;19(12).
  7. Jelski W, Mroczko B. Biochemical Markers of Colorectal Cancer - Present and Future. Cancer Manag Res. 2020;12:4789-97.
  8. Jalal JA, Othman Z, Anwar P. Immunohistochemical expression of clusterin in colorectal carcinoma. Zanco J Med Sci. 2021;25(2):544-50.
  9. Mohamad BJ, Zghair FA. Interleukin-6 expression in colorectal tumors in Iraqi patients. Int J Med Sci Public Health. 2019;8(4):1-8.
  10. Anele CC, Askari A, Navaratne L, Patel K, Jenkin JT, Faiz OD, et al. The association of age with the clinicopathological characteristics and prognosis of colorectal cancer: a UK single-centre retrospective study. Colorectal Dis. 2020;22(3):289-97.
  11. Mohamad BJ, Zghair KH, Zghair FA, Mohammed RS. Assessment the Immunohistochemical Expression of Cathepsin D in Iraqi Patients with Colorectal Carcinoma. Iraqi J Sci. 2015;56(4C):3337-45.
  12. Kamal LA, Jalal JA. Immunohistochemical expression of HER2/neu in colorectal carcinoma in Erbil city, Kurdistan Region. Zanco J Med Sci. 2019;23(3):421-8.
  13. Khalil KH, Al-Hassawi BA, Abdo JM. Histopathologicalevaluation Of Colorectal Carcinoma. Duhok Med J. 2018;12(2):45-67.
  14. Yaeger R, Chatila WK, Lipsyc MD, Hechtman JF, Cercek A, Sanchez-Vega F, et al. Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer. Cancer Cell. 2018;33(1):125-36 e3.
  1. Baran B, Mert Ozupek N, Yerli Tetik N, Acar E, Bekcioglu O, Baskin Y. Difference Between Left-Sided and Right-Sided Colorectal Cancer: A Focused Review of Literature. Gastroenterology Res. 2018;11(4):264-73.
  2. Alsafi RA, Metib NJ, Hameedi AD, Alqanbar MF. The clinical and Pathological characteristics of Colorectal Cancer in young age group in Karbala province/Iraq. Karbala J Med. 2018;11(2):4025-.
  3. Al-Hishma LWK. Proteinemia as a Prognostic Factor in Colorectal Cancers beyond Surgery and Chemotherapy. J Coloproctology. 2021;41(03):249-56.
  4. Wang L, Hirano Y, Heng G, Ishii T, Kondo H, Hara K, et al. Mucinous Adenocarcinoma as a High-risk Factor in Stage II Colorectal Cancer: A Propensity Score-matched Study from Japan. Anticancer Res. 2020;40(3):1651-9.
  5. Herman AM, Hawkins AT, Misso K, Issangya C, Tarmohamed M, Mremi A, et al. Colorectal Cancer in Northern Tanzania: Increasing Trends and Late Presentation Present Major Challenges. JCO Glob Oncol. 2020;6:375-81.
  6. Hosseini S, Bananzadeh AM, Salek R, Zare-Bandamiri M, Kermani AT, Mohammadianpanah M. Prognostic Significance of Mucinous Histologic Subtype on Oncologic Outcomes in Patients With Colorectal Cancer. Ann Coloproctol. 2017;33(2):57-63.
  7. Lan YT, Chang SC, Lin PC, Lin CC, Lin HH, Huang SC, et al. Clinicopathological and Molecular Features of Colorectal Cancer Patients With Mucinous and Non-Mucinous Adenocarcinoma. Front Oncol. 2021;11:620146.
  8. Al-Maghrabi J. Vimentin immunoexpression is associated with higher tumor grade, metastasis, and shorter survival in colorectal cancer. Int J Clin Exp Pathol. 2020;13(3):493.
  9. Sharkas GF, Arqoub KH, Khader YS, Tarawneh MR, Nimri OF, Al-Zaghal MJ, et al. Colorectal Cancer in Jordan: Survival Rate and Its Related Factors. J Oncol. 2017;2017:3180762.
  10. Abbood IS, Aziz IH. Genetic variation in B.R.A.F. gene among Iraqi colorectal cancer patients. Iraqi J Biotechnol. 2018;17(3).
  11. Mahmood NA, Abdulghany ZS, Al-Sudani IM. Expression of aldehyde dehydrogenase (ALDH1) and ATP Binding Cassette Transporter G2 (ABCG2) in Iraqi patients with colon cancer and the relation with clinicopathological features. Int J Mol Cell Med. 2018;7(4):234.
  12. Almuttairi RS, Isra’a M, Obied HJ. Cdx2 Expression In Colorectal Tumors In Iraqi Patients. Biochem Cell Arch. 2020;20(2):. 6653-9.
  13. Shaker OG, Senousy MA, Elbaz EM. Association of rs6983267 at 8q24, HULC rs7763881 polymorphisms and serum lncRNAs CCAT2 and HULC with colorectal cancer in Egyptian patients. Sci Rep. 2017;7(1):16246.
  14. Mo S, Dai W, Xiang W, Huang B, Li Y, Feng Y, et al. Survival Contradiction Between Stage IIA and Stage IIIA Rectal Cancer: A Retrospective Study. J Cancer. 2018;9(8):1466-75.
  1. Lee JH, Yu M, Kim SH, Lee JH, Sung SY, Jeong BK, et al. Pathologic Staging Inconsistency Between ypT4N0 (stage II) and ypT1-2N1 (stage III) After Preoperative Chemoradiotherapy and Total Mesorectal Excision in Rectal Cancer: A Multi-Institutional Study. Clin Colorectal Cancer. 2019;18(1):130-9.
  2. Taieb J, Karoui M, Basile D. How I treat stage II colon cancer patients. ESMO Open. 2021;6(4):100184.
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