1Société Francophone de Nutrithérapie et de Nutrigénétique Appliqu&eacut
2Inochi Care Private Limited, New Delhi-110017, India
3Institute of Molecular Biology and Biotechnology, BZ University, Multan, Pakistan
4- Société Francophone de Nutrithérapie et de Nutrigénétique Appliquée, Villeurbanne, France - Research and Development Departement, Nutri-Logics SA, Weiswampach, Luxembourg
5Research and Development Departement, Nutri-Logics SA, Weiswampach, Luxembourg
6- Académie Internationale de Médecine Dentaire Intégrative, Paris, France - Université Claude Bernard, Villeurbanne, France
چکیده
Context: COVID-19 caused serious threats to the world population as it spread all around the world rapidly. Existing medicines and vaccines were not able to cure and control this deadly disease. In this regard, several vaccines have been proposed and designed to effectively control the spread of this infection. Along with these vaccines, the general population should also adopt certain lifestyle interventions to strengthen their immune system and combat deadly viruses. Evidence Acquisition: We used Google Scholar and PubMed databases to find the related information by using different key terms such as ‘COVID-19’, ‘COVID-19 AND Vaccine efficacy’, ‘Lifestyle intervention AND COVID-19’ and “Lifestyle intervention AND Vaccines” etc. Only those articles were selected for this study that discussed the interactions of lifestyle intervention with the efficacy of COVID-19 vaccines. Results: Several previous clinical trials and scientific observations with influenza, polio, and other viral vaccines have demonstrated that vaccine response varies across individuals for antibody titer, independent of vaccine antigenicity. This different vaccine response observed among individuals is attributed to several factors such as dietary and nutritional habits, physical activity, stress and sleep deprivation, deficiency of micronutrients (minerals, vitamins), gut microbiota composition, immunosenescence, smoking, and drinking habits. Although, there is not much information about COVID-19 vaccine efficacy and lifestyle interventions is present, the experience with other vaccines can certainly be used to suggest lifestyle interventions to improve COVID-19 vaccine efficacy. These lifestyle interventions may boost antibody response against COVID-19 vaccines leading to higher protection from the disease, especially among elderly and immunocompromised people. Conclusion: In conclusion, the present review is an attempt to understand the role of various nutritional and psychological factors that leads to poor vaccine response and suggests certain nutritional and psychological interventions that can enhance vaccine efficacy and improve immune response against COVID-19 vaccines.