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R.Hashim, Zamn, A.Qasim, Qutaiba, H.ALabbood, Majid. (1401). The association of serum calcium and vitamin D with insulin resistance and beta-cell dysfunction among people with type 2 diabetes. سامانه مدیریت نشریات علمی, (), -. doi: 10.22092/ari.2022.357641.2081
Zamn R.Hashim; Qutaiba A.Qasim; Majid H.ALabbood. "The association of serum calcium and vitamin D with insulin resistance and beta-cell dysfunction among people with type 2 diabetes". سامانه مدیریت نشریات علمی, , , 1401, -. doi: 10.22092/ari.2022.357641.2081
R.Hashim, Zamn, A.Qasim, Qutaiba, H.ALabbood, Majid. (1401). 'The association of serum calcium and vitamin D with insulin resistance and beta-cell dysfunction among people with type 2 diabetes', سامانه مدیریت نشریات علمی, (), pp. -. doi: 10.22092/ari.2022.357641.2081
R.Hashim, Zamn, A.Qasim, Qutaiba, H.ALabbood, Majid. The association of serum calcium and vitamin D with insulin resistance and beta-cell dysfunction among people with type 2 diabetes. سامانه مدیریت نشریات علمی, 1401; (): -. doi: 10.22092/ari.2022.357641.2081

The association of serum calcium and vitamin D with insulin resistance and beta-cell dysfunction among people with type 2 diabetes

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مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 30 اردیبهشت 1401  XML
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2022.357641.2081
نویسندگان
Zamn R.Hashim email 1؛ Qutaiba A.Qasim2؛ Majid H.ALabbood3
1Clinical laboratory sciences department , College of pharmacy, University of Basra, Basra, Iraq
2College of pharmacy, Al-Ayen university, Thi-Qar, Iraq
3Alzahraa College of Medicine, University of Basra/Iraq
چکیده
Cross-sectional studies have linked vitamin D deficiency and alteration of calcium levels to an increased incidence of type 2 diabetes and insulin resistance. The aim of this study was to investigate possible correlation between blood vitamin D and calcium levels with insulin resistance and beta-cell dysfunction in type 2 diabetes, pre-diabetes, and healthy individuals. This cross-sectional study involved 300 participants. Participants were divided into three groups (n=100), type 2diabetic,prediabetic, and healthy subjects. In order to measure insulin resistance and β –cell function the HOMA IR and HOMA B were assessed respectively. Also the other parameters such as serum 25(OH)D, blood insulin (FPI), glucose (FBS), HbA1c, and calcium were assessd in this study. In simple regression analysis, high level of vitamin D is linked to lower levels of FBS, HbA1c, Insulin, and HOMA IR, and higher levels of HOMA B. Calcium has positive connection with FBS and HbA1c and negative connection with insulin level and HOMAB. Hypovitaminosis D may substantially influence diabetes patients' glycemic dysregulation. "An increased incidence of type 2 diabetes has been related to a disruption in calcium homeostasis. All in all an increament in calcium levels may have a role in developing type 2 diabetes".
کلیدواژه‌ها
Type 2M؛ 25 (OH) D؛ Calcium؛ vitamin D deficiency؛ insulin resistance
آمار
تعداد مشاهده مقاله: 33


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