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Islam, F, Akter, A, Mimi, A. A, Urmee, H, Islam, Md. R, Rahaman, Md. S, Mamun, A. A, Rahman, Md. M, Dhama, K, Emran, T. B. (1401). Neuropharmacological Effects of Chassalia curviflora (Rubiaceae) Leaves in Swiss Albino Mice Model. سامانه مدیریت نشریات علمی, 77(2), 881-890. doi: 10.22092/ari.2021.356880.1937
F Islam; A Akter; A. A Mimi; H Urmee; Md. R Islam; Md. S Rahaman; A. A Mamun; Md. M Rahman; K Dhama; T. B Emran. "Neuropharmacological Effects of Chassalia curviflora (Rubiaceae) Leaves in Swiss Albino Mice Model". سامانه مدیریت نشریات علمی, 77, 2, 1401, 881-890. doi: 10.22092/ari.2021.356880.1937
Islam, F, Akter, A, Mimi, A. A, Urmee, H, Islam, Md. R, Rahaman, Md. S, Mamun, A. A, Rahman, Md. M, Dhama, K, Emran, T. B. (1401). 'Neuropharmacological Effects of Chassalia curviflora (Rubiaceae) Leaves in Swiss Albino Mice Model', سامانه مدیریت نشریات علمی, 77(2), pp. 881-890. doi: 10.22092/ari.2021.356880.1937
Islam, F, Akter, A, Mimi, A. A, Urmee, H, Islam, Md. R, Rahaman, Md. S, Mamun, A. A, Rahman, Md. M, Dhama, K, Emran, T. B. Neuropharmacological Effects of Chassalia curviflora (Rubiaceae) Leaves in Swiss Albino Mice Model. سامانه مدیریت نشریات علمی, 1401; 77(2): 881-890. doi: 10.22092/ari.2021.356880.1937

Neuropharmacological Effects of Chassalia curviflora (Rubiaceae) Leaves in Swiss Albino Mice Model

Archives of Razi Institute
مقاله 46، دوره 77، شماره 2، خرداد و تیر 2022، صفحه 881-890    اصل مقاله (417.94 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2021.356880.1937
نویسندگان
F Islam1؛ A Akter1؛ A. A Mimi1؛ H Urmee2؛ Md. R Islam1؛ Md. S Rahaman1؛ A. A Mamun3؛ Md. M Rahman1؛ K Dhama4؛ T. B Emran* 5
1Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka, Bangladesh
2Department of Pharmaceutical Science, North South University, Dhaka, Bangladesh
3Molecular Pharmacology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang Province, China
4Division of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India
5Department of Pharmacy, BGC Trust University Bangladesh, Chittagong, Bangladesh
چکیده
The current study aimed to investigate the neuropharmacological properties of ethanol, acetone, and ethyl acetate leaf extracts of Chassalia curviflora (C. curviflora) in mouse models. The neuropharmacological properties of this plant were studied on Swiss albino mice at dosages of 50, 100, and 200 mg/kg body weight in thiopental sodium-induced sleeping time test, and at dosages of 100 and 200 mg/kg body weight in other tests. The extracts caused a marked reduction in the initiation and sleep length (P<0.05) in studies on thiopental sodium-induced sleeping time at dosages of 100 and 200 mg/kg and a significant decrease (P<0.05) was found in terms of unconstrained locomotor and explorative activities in both hole crossing and open field tests at dosages of 100 and 200 mg/kg. Furthermore, the extracts increased sleeping time with a dosage-dependent onset of action. The hole-board test extracts also reduced the number of head dips at dosages of 100 and 200 mg/kg (P<0.05). It was found in this study that C. curviflora had the best neuropharmacological properties at a dosage of 200 ml/kg. Our findings also showed that all of the extracts from C. curviflora were experimentally active in an in vivo model. The study results suggested that the leaves had strong anti-depressant and hypnotic CNS properties that might be exploited for neuropharmacological adjuvant therapy in conventional medicine. However, pharmacological studies are warranted to explore the active substances and the mode of action.
کلیدواژه‌ها
Chassalia curviflora؛ Gamma-aminobutyric acid؛ Latent period؛ Locomotor behavior؛ Neuropharmacological potential
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مراجع
  1. Sen N, Bulbul L, Hussain MS, Banik S, Choudhuri MSK. An in vivo study regarding analgesic and anxiolytic activity of methanolic extract of Typha elephantina Roxb. Clin Phytoscience. 2018;4(1):2.
  2. Stone J. Functional neurological disorders: the neurological assessment as treatment. Pract Neurol. 2016;16(1):7-17.
  3. Kendler KS. A Prehistory of the Diathesis-Stress Model: Predisposing and Exciting Causes of Insanity in the 19th Century. Am J Psychiatry. 2020;177(7):576-88.
  4. Sweetman A, Putland S, Lack L, McEvoy RD, Adams R, Grunstein R, et al. The effect of cognitive behavioural therapy for insomnia on sedative-hypnotic use: A narrative review. Sleep Med Rev. 2021;56:101404.
  5. Begum A, Biswas P, Shahed-Al-Mahmud M. Methanol extract of Spathodea campanulata P. (Beauv.) leaves demonstrate sedative and anxiolytic like actions on swiss albino mice. Clin Phytoscience. 2020;6(1):41.
  6. Schweitzer I, Maguire K, Ng C. Sexual side-effects of contemporary antidepressants: review. Aust N Z J Psychiatry. 2009;43(9):795-808.
  7. Islam N, Khan MF, Khatun MR, Nur S, Hanif NB, Kulsum U, et al. Neuropharmacological insights of African oil palm leaf through experimental assessment in rodent behavioral model and computer-aided mechanism. Food Biosci. 2021;40:100881.
  8. Anwar N, Ahmed N, Shahida T, Kabiruddin K, Aslam H. The Role of Mufarrehat (Exhilarants) in the Management of Depression: An Evidence Based Approach. Psychiatry J. 2017;20.
  9. Mendelson S. Herbal Treatment of Major Depression: Scientific Basis and Practical Use. 1st ed: CRC Press; 2019.
  10. Nabavi SM, Daglia M, Braidy N, Nabavi SF. Natural products, micronutrients, and nutraceuticals for the treatment of depression: A short review. Nutr Neurosci. 2017;20(3):180-94.
  11. Chukwuebuka E, Sharif N, Jabeen NS. Pharmacognosy and Prehistoric uses of Medicinal Plants. Phytochemistry. 1st ed.2018.
  1. Sandberg F, Corrigan D. Natural remedies: their origins and uses: CRC Press; 2001.
  2. Bodeker G, Ong C-K. WHO global atlas of traditional, complementary and alternative medicine: World Health Organization; 2005.
  3. Rebaya A, Belghith S, Baghdikian B, Leddet VM, Fathi M, Olivier E, et al. Total Phenolic, Total Flavonoid, Tannin Content, and Antioxidant Capacity of Halimium halimifolium (Cistaceae). J Appl Pharm Sci. 2015;5:052-7.
  4. Koudoro Y, Morand A, Andreea B, Olaye T, Agbangnan D CP, Pascal C, et al. Phytochemical analysis, antioxidant and anti-inflammatory activities of Chassalia kolly leaves extract, a plant used in Benin to treat skin illness. GSC Biol Pharm Sci. 2021;15:63-072.
  5. Mahajon B, Remadevi R. Folk Medicine For Yakrit Vikaara (Liver Disorder) -A Scientific Review. 2015;3:1828-47.
  6. Nair C, Mohanan N, . Medicinal plants of India (with special reference to Ayurveda). Nag Publishers; 1998.
  7. Greeshma K, Kumar NM, Krishna JG, Phytochemistry. Preliminary pharmacognostical and phytochemical analysis of Chassalia curviflora (wall.) Thwaites roots. J Pharmacogn. 2018;7(6):1043-8.
  8. Salleh WMNHW, Nafiah M, Khamis S. Chemical composition and acetylcholinesterase inhibitory activity of Chassalia curviflora (Wall.) Thwaites essential oil. Riv Ital Sostanze Grasse. 2021;98:139-43.
  9. Henriques AT, Melo AA, Moreno PRH, Ene LL, Henriques JAP, Schapoval EES. Ervatamia coronaria: chemical constituents and some pharmacological activities.J Ethnopharmacol. 1996;50(1):19-25.
  10. Anuar TAFT, Azlini I. Southeast Asian Medicinal Plants with Angiotensin Converting Enzyme (ACE) Inhibition Properties. Pharmacog J. 2020;12(6).
  11. Hafiz W, Zilani MNH, Sultana NA, Isalm MM, Anisuzzman M, Hossain MG. Neuropharmacological potential of Ceriscoides turgida (Roxb.) leaf and root in mice. Clin Phytoscience. 2019;5(1):5.
  12. Aziz MAI, Barua N, Tareq AM, Alam N, Prova RJ, Mamun MN, et al. Possible neuropharmacological effects of Adenia trilobata (Roxb.) in the Swiss albino mice model. Future J Pharm Sci. 2020;6(1):72.
  13. Awaludin A, Kartina K, Maulianawati D, Manalu W, Andriyanto A, Septiana R, et al. Phytochemical screening and toxicity of ethanol extract of Sauropus androgynus. Biodivers J. 2020;21(7).
  14. Bruce RD. An up-and-down procedure for acute toxicity testing. Fundam Appl Toxicol . 1985;5(1):151-7.
  15. Ali MS, Dash PR, Nasrin M. Study of sedative activity of different extracts of Kaempferia galanga in Swiss albino mice. BMC Complement Altern Med. 2015;15:158.
  16. Uddin SJ, Shilpi JA, Rahman MT, Ferdous M, Rouf R, Sarker SD. Assessment of neuropharmacological activities of Pandanus foetidus (Pandanaceae) in mice. Die Pharmazie. 2006;61(4):362-4.
  17. Sheikh BY, Zihad SM, Sifat N, Uddin SJ, Shilpi JA, Hamdi OA, et al. Comparative study of neuropharmacological, analgesic properties and phenolic profile of Ajwah, Safawy and Sukkari cultivars of date palm (Phoenix dactylifera). Orient Pharm Exp Med. 2016;16(3):175-83.
  18. Anisuzzman M, Hasan MM, Acharzo AK, Das AK, Rahman S. In Vivo and In Vitro Evaluation of Pharmacological Potentials of Secondary Bioactive Metabolites of Dalbergia candenatensis Leaves. Evid Based Complement Alternat Med. 2017;2017:5034827.
  19. Wong CG, Bottiglieri T, Snead OC, 3rd. GABA, gamma-hydroxybutyric acid, and neurological disease. Ann Neurol. 2003;54 Suppl 6:S3-12.
  20. Gahlot K, Lal VK, Jha S. Anticonvulsant potential of ethanol extracts and their solvent partitioned fractions from Flemingia strobilifera root. Pharmacognosy Res. 2013;5(4):265-70.
  21. Ahn Y, Han SH, Kim MG, Hong KB, Kim WJ, Suh HJ, et al. Anti-depressant effects of ethanol extract from Cannabis sativa (hemp) seed in chlorpromazine-induced Drosophila melanogaster depression model. Pharm Biol. 2021;59(1):998-1007.
  22. Kumar K, Sharma S, Kumar P, Deshmukh R. Therapeutic potential of GABA(B) receptor ligands in drug addiction, anxiety, depression and other CNS disorders. Pharmacol Biochem Behav. 2013;110:174-84.
  23. Sultana T, Mannan MA, Ahmed T. Evaluation of central nervous system (CNS) depressant activity of methanolic extract of Commelina diffusa Burm. in mice. Clin Phytoscience. 2018;4(1):5.
  24. Syeda NF, Hemalatha G, Smitha T, Rama M. Assessment of Neuropharmacological Profile of Ethanolic Extract of Lawsonia Inermis Flowers. Mapana J Sci .2020;19(4):37.
  25. Auniq RBJ, Chy MNU, Adnan M, Chowdhury MR, Dutta T, Ibban SS, et al. Evaluation of anxiolytic, sedative, and antioxidant activities of Vitex peduncularis Wall. leaves and investigation of possible lead compounds through molecular docking study. Adv Tradit Med. 2021;21(3):507-18.
  26. Himanshu, Dharmila, Sarkar D, Nutan. A Review of Behavioral Tests to Evaluate Different Types of Anxiety and Anti-anxiety Effects. Clin Psychopharmacol Neurosci. 2020;18(3):341-51.
  27. Thakur VD, Mengi SA. Neuropharmacological profile of Eclipta alba (Linn.) Hassk. J Ethnopharmacol. 2005;102(1):23-31.
  28. Dixit A, Singh H, Sharma R, Sharma A. Estimation of antioxidant and antibacterial activity of crude extracts of Thevetia peruviana. Int J Pharm Pharm Sci. 2015;7(2):55-9.
  29. Haque MA, Jantan I, Abbas Bukhari SN. Tinospora species: An overview of their modulating effects on the immune system. J Ethnopharmacol. 2017;207:67-85.
  30. Moazzem Hossen SM, Akramul Hoque Tanim M, Shahadat Hossain M, Ahmed Sami S, Uddin Emon N. Deciphering the CNS anti-depressant, antioxidant and cytotoxic profiling of methanol and aqueous extracts of Trametes versicolor and molecular interactions of its phenolic compounds. Saudi J Biol Sci. 2021;28(11):6375-83.
  1. Salman M, Tabassum H, Parvez S. Tannic Acid Provides Neuroprotective Effects Against Traumatic Brain Injury Through the PGC-1alpha/Nrf2/HO-1 Pathway. Mol Neurobiol. 2020;57(6):2870-85.
  2. Kinda PT, Zerbo P, Guenne S, Compaore M, Ciobica A, Kiendrebeogo M. Medicinal Plants Used for Neuropsychiatric Disorders Treatment in the Hauts Bassins Region of Burkina Faso. Medicine. 2017;4(2).
  3. Akindele A, Sanni HA, Edeh P. Anxiolytic activity of aerial part hydroethanolic extract of Allium ascalonicum Linn. (Liliaceae) in mice. J Funct Food Health Dis. 2012;2:448-59.
  4. Moniruzzaman M, Atikur Rahman M, Ferdous A. Evaluation of Sedative and Hypnotic Activity of Ethanolic Extract of Scoparia dulcis Linn. Evid Based Complement Alternat Med. 2015;2015:873954.
  5. Kennedy DO, Wightman EL. Herbal extracts and phytochemicals: plant secondary metabolites and the enhancement of human brain function. Adv Nutr. 2011;2(1):32-50.
  6. Rahman SM, Rana S, Islam M, Kumer A, Hassan M, Biswas T, et al. Evaluation of Anxiolytic and Sedative-Like Activities of Methanolic Extract of Euphorbia hirta Leaves in Mice. J Pharm Pharmacol. 2019;10:283-97.
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