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Hassan Abood, A, Khteer Al-Hadraawy, S, Abdulhur Alibraheemi, N, Zabibah, R. S, Khalfa, H. M. (1401). Histological Changes and Ghrelin, P-Selectin, and Leptin Parameter in Patients with Hepatic Hydatidosis in Iraq. سامانه مدیریت نشریات علمی, 77(2), 585-590. doi: 10.22092/ari.2021.356856.1927
A Hassan Abood; S Khteer Al-Hadraawy; N Abdulhur Alibraheemi; R. S Zabibah; H. M Khalfa. "Histological Changes and Ghrelin, P-Selectin, and Leptin Parameter in Patients with Hepatic Hydatidosis in Iraq". سامانه مدیریت نشریات علمی, 77, 2, 1401, 585-590. doi: 10.22092/ari.2021.356856.1927
Hassan Abood, A, Khteer Al-Hadraawy, S, Abdulhur Alibraheemi, N, Zabibah, R. S, Khalfa, H. M. (1401). 'Histological Changes and Ghrelin, P-Selectin, and Leptin Parameter in Patients with Hepatic Hydatidosis in Iraq', سامانه مدیریت نشریات علمی, 77(2), pp. 585-590. doi: 10.22092/ari.2021.356856.1927
Hassan Abood, A, Khteer Al-Hadraawy, S, Abdulhur Alibraheemi, N, Zabibah, R. S, Khalfa, H. M. Histological Changes and Ghrelin, P-Selectin, and Leptin Parameter in Patients with Hepatic Hydatidosis in Iraq. سامانه مدیریت نشریات علمی, 1401; 77(2): 585-590. doi: 10.22092/ari.2021.356856.1927

Histological Changes and Ghrelin, P-Selectin, and Leptin Parameter in Patients with Hepatic Hydatidosis in Iraq

Archives of Razi Institute
مقاله 10، دوره 77، شماره 2، خرداد و تیر 2022، صفحه 585-590    اصل مقاله (575.16 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2021.356856.1927
نویسندگان
A Hassan Abood* 1؛ S Khteer Al-Hadraawy1؛ N Abdulhur Alibraheemi2؛ R. S Zabibah3؛ H. M Khalfa1
1Faculty of Sciences, University of Kufa, Kufa, Iraq
2College of Medical Sciences, University of Kufa, Kufa, Iraq
3Department of Radiology Techniques, College of Medical Technology, The Islamic University, Najaf, Iraq
چکیده
Humans and animals are affected by hydatid cyst disease as a worldwide zoonotic disease, which is caused by the metacestode stage of Echinococcus spp. This study was performed to evaluate the histological change of liver and blood concentrations of biomarkers, such as ghrelin, p-selectin, and leptin, in humans infected with hydatid cyst. A total of 30 surgical specimens of liver and blood of infected humans and 30 healthy individuals as a control group were evaluated. Liver tissue sections in cases infected with hydatid cyst and control group, histological abnormalities in the liver, including fibrosis, increased inflammatory cells, dystrophic areas, and necrosis were compared in this study. In addition, serum leptin levels were significantly lower in patients with hydatid cyst disease than in the control group (P-value<0.05), whereas p-selectin and ghrelin levels significantly decreased in patients (P-value<0.05). The results of this research can be effective in improving and promoting the treatment programs of hydatidosis.
کلیدواژه‌ها
Ghrelin؛ Histological change؛ Hydatid disease؛ Kufa؛ Leptin؛ P-selectin
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مراجع
  1. Bhutani N, Kajal P. Hepatic echinococcosis: A review. Ann Med Surg. 2018;36:99-105.
  2. Shavalier MA, Faisal M, Moser ML, Loch TP. Parasites and microbial infections of lamprey (order Petromyzontiformes Berg 1940): A review of existing knowledge and recent studies. J Great Lakes Res. 2021.
  3. Filippou D, Tselepis D, Filippou G, Papadopoulos V. Advances in liver echinococcosis: diagnosis and treatment. Clin Gastroenterol Hepatol. 2007;5(2):152-9.
  4. Hayajneh FMF, Althomali AMH, Nasr AT. Prevalence and characterization of hydatidosis in animals slaughtered at Al Taif abattoir, Kingdom of Saudi Arabia.Open J Anim Sci. 2014;2014.
  5. Elissondo MC, Dopchiz MC, Denegri G. Human hydatidosis in Mar del Plata, Buenos Aires province, Argentina,(1992-1995): A preliminary study. Parasitología latinoamericana. 2002;57(3-4):124-8.
  6. Polat E, Aslan M, Cakan H, Saribas S, Ipek T, Kocazeybek B. The effects of albendazole and povidone iodine for hydatid cysts protoscoleces, ın-vitro and-vivo. Afr J Microbiol Res. 2009;3(11):743-6.
  7. Ma X, Bao G, Wan J, Liao D, Yin S, Meng X, et al. Therapeutic effects of Sophora moorcroftiana alkaloids in combination with albendazole in mice experimentally infected with protoscolices of Echinococcus granulosus. Braz J Med Biol. 2007;40:1403-8.
  8. Feng Y, Ma X, Deng L, Yao B, Xiong Y, Wu Y, et al. Role of selectins and their ligands in human implantation stage. Glycobiology. 2017;27(5):385-91.
  9. Ramacciotti E, Myers Jr DD, Wrobleski SK, Deatrick KB, Londy FJ, Rectenwald JE, et al. P-selectin/PSGL-1 inhibitors versus enoxaparin in the resolution of venous thrombosis: a meta-analysis. Thromb Res. 2010;125(4):e138-e42.
  10. Serbina NV, Jia T, Hohl TM, Pamer EG. Monocyte-mediated defense against microbial pathogens. Annu Rev Immunol. 2008;26:421-52.
  11. Myers MG, Cowley MA, Münzberg H. Mechanisms of leptin action and leptin resistance. Annu Rev Physiol. 2008;70:537-56.
  12. Zaralis K, Tolkamp BJ, Houdijk JG, Wylie AR, Kyriazakis I. Consequences of protein supplementation for anorexia, expression of immunity and plasma leptin concentrations in parasitized ewes of two breeds. Br J Nutr. 2008;101(4):499-509.
  13. Parvin Z, Iraj MD, Minoo S, Fatemeh K. Effects of Toxoplasma gondii infection on anxiety, depression and ghrelin level in male rats. J Parasit Dis. 2016;40(3):688-93.
  14. Al-Hadraawy SK, Al-ghurabi ME, Al-musawi MM, Alzeyadi M. Ghrelin and melatonin as biomarkers in patients with giardiasis. Biotechnol Biotechnol Equip. 2016;30(3):553-7.
  15. Khteer Al-Hadraawy S, Al-Shebly F, Abood A, Kadhum N. Correlation Study between Biological Markers in Patients with Entamoeba Histolytica Parasite. Biochem Cell Arch. 2019;19:125-9.
  16. Dakhale GN, Hiware SK, Turankar AV, Mahatme MS, Pimpalkhute SA. Basic Statistical Analysis for Original Studies. A Guide to the Scientific Career: Virtues, Communication, Research and Academic Writing. 2019:591-607.
  17. Mohy AA, Aljanaby AAJ, Al-Hadraawy SK. Evaluation of Eosinophilic cationic protein and some immunological markers in patients infected with Scabies. J Pure Appl Microbiol. 2019;13(3):1737-43.
  18. Baldo BA, Pham NH. Biologics: Monoclonal Antibodies for Non-cancer Therapy, Cytokines, Fusion Proteins, Enzymes, and Hormones. Drug Allergy: Springer; 2021. p. 533-93.
  19. Guo X, Roberts MR, Becker SM, Podd B, Zhang Y, Chua S, et al. Leptin signaling in intestinal epithelium mediates resistance to enteric infection by Entamoeba histolytica. Mucosal Immunol. 2011;4(3):294-303.
  20. Issekutz AC, Issekutz TB. The role of E-selectin, P-selectin, and very late activation antigen-4 in T lymphocyte migration to dermal inflammation. J Immunol. 2002;168(4):1934-9.
  21. Zaph C, Scott P. Th1 cell-mediated resistance to cutaneous infection with Leishmania major is independent of P-and E-selectins. J Immunol. 2003;171(9):4726-32.
  1. Lawrence MB, Springer TA. Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins. Cell. 1991;65(5):859-73.
  2. Al-Dujaili MN, Al-Hadraawy SK, Abood AH, Kadhim NJ. Study of P-selectin and some markers in patients with Giardia lamblia parasite. J Pharm Sci Res. 2018;10(7):1723-6.
  3. Nath J. Digesting Foods and Fads: McFarland; 2021.
  4. El Saftawy EA, Abdelmoktader A, Sabry MM, Alghandour SM. Histological and immunological insights to hydatid disease in camels. Vet Parasitol: Reg Stud Rep. 2021;26:100635.
  5. Torgerson P. Economic effects of echinococcosis. Acta tropica. 2003;85(2):113-8.
  6. Al Se M. Gross and histological comparison of hydatid cyst infection in livers of sheep and cows. Al-Qadisiyah Journal of Veterinary Medicine Sciences. 2012;11(2):94-101.
  7. Radhwan RS, Al-Nasiri FS. Detection of infection with hydatid cysts in abattoirs animals at Kirkuk governorate, Iraq. Tikrit J Pure sci. 2021;26(4):24-32.
  8. Singh B, Sharma R, Sharma J, Mahajan V, Gill J. Histopathological changes associated with E. granulosus echinococcosis in food producing animals in Punjab (India). J Parasit Dis. 2016;40(3):997-1000.
  9. Khadidja H, Achour Y, Houcin B, Vasile C. Histological appearance of Echinococcus granulosus in the camel species in Algeria. Bulletin UASVM Vet Med. 2014;71:79-84.
  10. Ibrahim SEA. Pathological, histochemical and immunohistochemical studies of lungs and livers of cattle and sheep infected with hydatid disease. 2014.
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