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Hassan Abood, A, Khteer Al-Hadraawy, S, Abdulhur Alibraheemi, N, Zabibah, R. S, Khalfa, H. M. (1401). Histological Changes and Ghrelin, P-Selectin, and Leptin Parameter in Patients with Hepatic Hydatidosis in Iraq. سامانه مدیریت نشریات علمی, 77(2), 585-590. doi: 10.22092/ari.2021.356856.1927
A Hassan Abood; S Khteer Al-Hadraawy; N Abdulhur Alibraheemi; R. S Zabibah; H. M Khalfa. "Histological Changes and Ghrelin, P-Selectin, and Leptin Parameter in Patients with Hepatic Hydatidosis in Iraq". سامانه مدیریت نشریات علمی, 77, 2, 1401, 585-590. doi: 10.22092/ari.2021.356856.1927
Hassan Abood, A, Khteer Al-Hadraawy, S, Abdulhur Alibraheemi, N, Zabibah, R. S, Khalfa, H. M. (1401). 'Histological Changes and Ghrelin, P-Selectin, and Leptin Parameter in Patients with Hepatic Hydatidosis in Iraq', سامانه مدیریت نشریات علمی, 77(2), pp. 585-590. doi: 10.22092/ari.2021.356856.1927
Hassan Abood, A, Khteer Al-Hadraawy, S, Abdulhur Alibraheemi, N, Zabibah, R. S, Khalfa, H. M. Histological Changes and Ghrelin, P-Selectin, and Leptin Parameter in Patients with Hepatic Hydatidosis in Iraq. سامانه مدیریت نشریات علمی, 1401; 77(2): 585-590. doi: 10.22092/ari.2021.356856.1927

Histological Changes and Ghrelin, P-Selectin, and Leptin Parameter in Patients with Hepatic Hydatidosis in Iraq

Archives of Razi Institute
مقاله 10، دوره 77، شماره 2، خرداد و تیر 2022، صفحه 585-590    اصل مقاله (575.16 K)
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2021.356856.1927
نویسندگان
A Hassan Abood* 1؛ S Khteer Al-Hadraawy1؛ N Abdulhur Alibraheemi2؛ R. S Zabibah3؛ H. M Khalfa1
1Faculty of Sciences, University of Kufa, Kufa, Iraq
2College of Medical Sciences, University of Kufa, Kufa, Iraq
3Department of Radiology Techniques, College of Medical Technology, The Islamic University, Najaf, Iraq
چکیده
Humans and animals are affected by hydatid cyst disease as a worldwide zoonotic disease, which is caused by the metacestode stage of Echinococcus spp. This study was performed to evaluate the histological change of liver and blood concentrations of biomarkers, such as ghrelin, p-selectin, and leptin, in humans infected with hydatid cyst. A total of 30 surgical specimens of liver and blood of infected humans and 30 healthy individuals as a control group were evaluated. Liver tissue sections in cases infected with hydatid cyst and control group, histological abnormalities in the liver, including fibrosis, increased inflammatory cells, dystrophic areas, and necrosis were compared in this study. In addition, serum leptin levels were significantly lower in patients with hydatid cyst disease than in the control group (P-value<0.05), whereas p-selectin and ghrelin levels significantly decreased in patients (P-value<0.05). The results of this research can be effective in improving and promoting the treatment programs of hydatidosis.
کلیدواژه‌ها
Ghrelin؛ Histological change؛ Hydatid disease؛ Kufa؛ Leptin؛ P-selectin
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