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Ali Hamza, Muqdam, AAbdulhameed, Abdulameer, Ali Mansour, Abbas. (1400). Total testosterone to estradiol ratio as a predictor marker against metabolic syndrome in men. سامانه مدیریت نشریات علمی, (), -. doi: 10.22092/ari.2021.356607.1878
Muqdam Ali Hamza; Abdulameer AAbdulhameed; Abbas Ali Mansour. "Total testosterone to estradiol ratio as a predictor marker against metabolic syndrome in men". سامانه مدیریت نشریات علمی, , , 1400, -. doi: 10.22092/ari.2021.356607.1878
Ali Hamza, Muqdam, AAbdulhameed, Abdulameer, Ali Mansour, Abbas. (1400). 'Total testosterone to estradiol ratio as a predictor marker against metabolic syndrome in men', سامانه مدیریت نشریات علمی, (), pp. -. doi: 10.22092/ari.2021.356607.1878
Ali Hamza, Muqdam, AAbdulhameed, Abdulameer, Ali Mansour, Abbas. Total testosterone to estradiol ratio as a predictor marker against metabolic syndrome in men. سامانه مدیریت نشریات علمی, 1400; (): -. doi: 10.22092/ari.2021.356607.1878

Total testosterone to estradiol ratio as a predictor marker against metabolic syndrome in men

Archives of Razi Institute
مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 19 آبان 1400  XML
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22092/ari.2021.356607.1878
نویسندگان
Muqdam Ali Hamza email 1؛ Abdulameer AAbdulhameed2؛ Abbas Ali Mansour1
1Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC), University of Basrah, Basrah, Iraq
2College of Medicine, University of Basrah, Basrah, Iraq
چکیده
Nowadays, the metabolic syndrome (MetS) represents a global health challenge in developed and developing countries. The sex hormones disorders in men are related to much clinical co-morbidity. This study was aimed to evaluate the total testosterone (TT) to estradiol (E2) ratio as a predictor marker of MetS. For this reason, case control studies on convenient sample of 88 MetS patients and 88 healthy participants (control), with age range of 18-69 years old were selected from outpatient clinic. They were chosen thorough a following medical history and physical examination, which included waist circumference and blood pressure, serum E2, TT, fasting blood glucose (FBG), triglyceride(TG), and high density lipoprotein-cholesterol (HDL-C). Diagnosis of MetS was confirmed according to the National Cholesterol Education Program Adult Treatment Panel III. The findings revealed that the mean of TT level was significantly lower among patients with MetS (p<0.001), while mean E2 level was significantly increased among patients with MetS (p<0.001). The mean TT to E2 ratio was significantly lower among patients with MetS (OR=9.6, p<0.001). There was a significant correlation between MetS components and TT to E2 ratio especially with waist circumference (WC) (r = - 0.49, p< 0.0001). The means of weight, WC, blood pressure and FBG levels were significantly increased in patients with MetS (p<0.001, p<0.001, p<0.001, p = 0.04 respectively). The lipid profile of patients with MetS was abnormal; TG, p<0.001, HDL-C, p<0.001 respectively. In conclusion, the TT to E2 ratio is a significant predictor of MetS in men.
کلیدواژه‌ها
Metabolic syndrome؛ Testosterone؛ Estradiol؛ Iraq
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تعداد مشاهده مقاله: 30


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