Vakhitov, B. I, Sergeevich Raginov, I, Lvovich Zefirov, T, Khatybovich Vakhitov, I, Ildarovich Vakhitov, L. (1400). Contractile Responses of Murine Hearts Subjected to Different Modes of Motor Activity to Traumatic Brain Injury. سامانه مدیریت نشریات علمی, 76(3), 631-638. doi: 10.22092/ari.2021.355326.1674
B. I Vakhitov; I Sergeevich Raginov; T Lvovich Zefirov; I Khatybovich Vakhitov; L Ildarovich Vakhitov. "Contractile Responses of Murine Hearts Subjected to Different Modes of Motor Activity to Traumatic Brain Injury". سامانه مدیریت نشریات علمی, 76, 3, 1400, 631-638. doi: 10.22092/ari.2021.355326.1674
Vakhitov, B. I, Sergeevich Raginov, I, Lvovich Zefirov, T, Khatybovich Vakhitov, I, Ildarovich Vakhitov, L. (1400). 'Contractile Responses of Murine Hearts Subjected to Different Modes of Motor Activity to Traumatic Brain Injury', سامانه مدیریت نشریات علمی, 76(3), pp. 631-638. doi: 10.22092/ari.2021.355326.1674
Vakhitov, B. I, Sergeevich Raginov, I, Lvovich Zefirov, T, Khatybovich Vakhitov, I, Ildarovich Vakhitov, L. Contractile Responses of Murine Hearts Subjected to Different Modes of Motor Activity to Traumatic Brain Injury. سامانه مدیریت نشریات علمی, 1400; 76(3): 631-638. doi: 10.22092/ari.2021.355326.1674
Contractile Responses of Murine Hearts Subjected to Different Modes of Motor Activity to Traumatic Brain Injury
1Traumatologist-orthopedist GAUZ "RKB", Ministry of Health of the Republic of Tatarstan, Kazan Federal University, Kazan, Russia
2Department of Biomedical Engineering and Innovation Management, Kazan Federal University , Kazan, Russia, ORCID - 0000-0002-5279-2623
3Institute of Fundamental Medicine and Biology, Head of the Department of Human Health Protection, Kazan Federal University, Kazan, Russia, ORCID - http://orcid.org/0000-0001-9557-1639
4Engineering Institute, Department of Biomedical Engineering and Innovation Management, Kazan Federal University, Kazan, Russia, ORCID - http://orcid.org/0000-0001-9281-2791
5Institute of Fundamental Medicine and Biology, Department of Human Health Protection, Kazan Federal University, Kazan, Russia, ORCID 0000-0003-0649-5393
چکیده
For the first time ever, this research studied the response of stroke volume in animals to various modes of motor activity after a traumatic brain injury. The study showed a pronounced decrease in stroke volume (SV) the first day after modeling an open craniocerebral injury in rats of all age groups. At the same time, the smallest SV response to brain injury was observed in immature animals. After modeling a traumatic brain injury, it was found that the implementation of systematic dynamic exercises by animals of pre-senile agedoes not contribute to increase SV; a significant increase in SV after a traumatic brain injury is observed only in immature animals. It was revealed that limiting physical activity and the performance of isometric exercises after a traumatic brain injury restrain a natural increase in SV in immature rat pups and decrease SV in sexually mature and pre-senile animals.
Ovsiannikov DM, Chekhonatskii AA, Kolesov VN, AI. B. Social and epidemiological aspects of traumatic brain injury (review). J Med Sci Res. 2012;8(3):777-85.
Raginov IS, Egorov VI, Valiullin LR, Vindzorova M, IN. C. Changes in the expression of different types of p2 receptors in epithelial and nervous tissues during posttraumatic regeneration in rats. Genes Cells. 2017;12(3):203.
Raginov IS, Iasieva MR, MA. M. The effect of p2y and p2x receptor blockers on the cognitive functions in mice. Morphol. 2014;145(3):234.
RR. N. The pumping function of the heart of the developing organism and its regulation in muscle training. Diss MD Biol. 1999;8(1):455.
Sitdikov FG, Anikina TA, Gil'mutdinova RI. Adrenergic and cholinergic control on the heart in rat ontogenesis. Bull Exp Biol Med. 1998;126(3):925-7.
Zefirov T. Nervous regulation of the heart rate in rats in postnatal ontogenesis: Author. diss. MD-Kazan; 1999.
Zefirov TL, Chershintseva NN, Bilalova GA, Sitdikov FG, Dikopolskaia NB, MV. S. Adrenergic receptors in dopaminergic regulation of myocardial contractility in growing rats. Receptor intracellular signaling. 2019;7(2):194-7.
TL. Z, NV. S. The effect of stimulation of the vagus nerve on the heart rate of rats with Obsidan-blocked β-adrenoceptor. Bull Exp Biol Med. 1998;12(1):612-4.
TL. Z, RK. B, AM. K, II. K, NI. Z. The effect of experimental myocardial ischemia on the postoperative state of rats. Physiol Pathology blood circulation VII All-Russian School Conference Int participation. 2020;5(1):22.
Kubicek WG, Kamegis JW, Patterson RP, Witsoe DA, RH. M. Development and evaluation of an impedance cardiac output system. Aerosp Med. 1966;37:8-12.
Li M, West JW, Lai Y, Scheuer T, Catterall WA. Functional modulation of brain sodium channels by cAMP-dependent phosphorylation. Neuron. 1992;8(6):1151-9.