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An Overview of the Most Important Medicinal Plants that Affect Hypertension and Their Antihypertensive Mechanism | ||
| Journal of Medicinal plants and By-product | ||
| مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 17 آبان 1399 اصل مقاله (981.69 K) | ||
| نوع مقاله: Research Paper | ||
| شناسه دیجیتال (DOI): 10.22092/jmpb.2020.351544.1248 | ||
| نویسندگان | ||
Gholam Basati1؛ Fatemeh Mehrabi Rad2، 3؛ Arash Momeni Safarabadi2، 3؛ Pegah Shakib4؛ Mehrnoosh Sedighi  5؛ Mostafa Cheraghi5
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| 1Biotechnology And Medicinal Plants Research Center,Ilam University of Medical Sciences, Ilam Iran | ||
| 2Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran | ||
| 3Student Research Committee, Health Nursing, Lorestan University of Medical Sciences, Khorramabad, Iran | ||
| 4Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khoramabad, Iran | ||
| 5Razi Herbal Medicines Research Center & Cardiovascular Research Center, Shahid Rahimi Hospital, Lorestan University of Medical Sciences, Khoramabad, Iran | ||
| چکیده | ||
| Despite the increased awareness about high blood pressure, high blood pressure remains a major cause of morbidity and mortality in the community. Medication and high blood pressure can be treated with medication and non-medication. The high prevalence of high blood pressure around the world and the development of serious and dangerous complications on the organs of the body, has made this disease a major health problem in all societies and is a major cause of cardiovascular disease. Concerns about the side effects of chemical drugs lead to misuse of medications, intolerance to patients, and, consequently, impaired control of the disease. That's why today there is a new approach to medicinal plants and a lot of research is being done on medicinal plants. The purpose of this study is to review the introduction of plants and provide the mechanism of action of the most effective medicinal plants in the treatment of hypertension. This paper examines the use of electronic search in articles published in various Internet databases and reference books on the mechanism of action of various plants in the treatment of hypertension by affecting the molecular mechanisms involved in the disease. According to the results of medicinal plants such as Camellia sinensis, Berberis vulgaris, Rosa damascene, Punica granatum, Olea europaea, Teucrium polium, Lavandula angustifolia, Urtica Dioica, Cinnamomum zeylanicum, Glycyrrhiza glabra, Allium sativum and Juglans regia are the most important medicinal plants affecting high blood pressure. Studies have shown that medicinal plants with various mechanisms such as vasodilation, production of nitric oxide (NO), calcium channel blockers, increased potassium, inhibition of renin-angiotensin pathway, and activation of intracellular CGMP and expansion of vasodilator effect to hypertension treatment. | ||
| کلیدواژه‌ها | ||
| Hypertension؛ Medicinal Plants؛ Molecular Mechanisms | ||
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آمار تعداد مشاهده مقاله: 12 تعداد دریافت فایل اصل مقاله: 18 |
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