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Daneshyar, Fahimeh, jalili, mahsa, sharifi, somayeh, Najafi, Azar. (1399). Eradication of Biofilm Formation by Crocus sativus Alcoholic Extract in Streptococcus mutans Clinical Isolates. سامانه مدیریت نشریات علمی, (), -. doi: 10.22092/jmpb.2020.341970.1184
Fahimeh Daneshyar; mahsa jalili; somayeh sharifi; Azar Najafi. "Eradication of Biofilm Formation by Crocus sativus Alcoholic Extract in Streptococcus mutans Clinical Isolates". سامانه مدیریت نشریات علمی, , , 1399, -. doi: 10.22092/jmpb.2020.341970.1184
Daneshyar, Fahimeh, jalili, mahsa, sharifi, somayeh, Najafi, Azar. (1399). 'Eradication of Biofilm Formation by Crocus sativus Alcoholic Extract in Streptococcus mutans Clinical Isolates', سامانه مدیریت نشریات علمی, (), pp. -. doi: 10.22092/jmpb.2020.341970.1184
Daneshyar, Fahimeh, jalili, mahsa, sharifi, somayeh, Najafi, Azar. Eradication of Biofilm Formation by Crocus sativus Alcoholic Extract in Streptococcus mutans Clinical Isolates. سامانه مدیریت نشریات علمی, 1399; (): -. doi: 10.22092/jmpb.2020.341970.1184

Eradication of Biofilm Formation by Crocus sativus Alcoholic Extract in Streptococcus mutans Clinical Isolates

Journal of Medicinal plants and By-product
مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 18 مرداد 1399  XML اصل مقاله (693.58 K)
نوع مقاله: Research Paper
شناسه دیجیتال (DOI): 10.22092/jmpb.2020.341970.1184
نویسندگان
Fahimeh Daneshyar email 1؛ mahsa jalili2؛ somayeh sharifi3؛ Azar Najafi4
1Department of Pediatric Dentistry, School of Dentistry, Hamedan University of Medical Sciences, Hamadan, Iran.
2Department of Microbiology, , Ilam University of Medical Sciences, Ilam, Iran.
3Student Research Committee, Hamadan University of Medical Sciences, Hamadan, Iran
4Razi Herbal Medicines Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran
چکیده
Abstract
Despite major advances in oral health in the past decades, but tooth decay is one of the most common preventable diseases in the worldwide. Now days, Streptococcus mutans is discussed as one of the most important challenges in tooth decay. In the other hand, medicinal herbs can be considered as an effective weapon against infectious diseases. The purpose of the current study was to investigate the biofilm formation in S. mutans clinical isolates and to evaluate the anti-biofilm properties of C. sativus against S. mutans clinical isolates. In this study, thirty dental plaque samples were collected from patients with referring to treatment centers of Hamadan University of Medical Sciences. Then, identification of samples was performed by standard methods. Biofilm formation was evaluated on S. mutans clinical isolates. Afterwards, C. sativus alcoholic extract was applied as an anti-biofilm formation in S. mutans clinical isolates. Our results demonstrated that a significant number of S. mutans samples were identified as strong, moderate and week biofilm producers. Then, C. sativus in 60 g/ml, 30 g/ml and 8 g/ml were able to eradicated strong, moderate and week biofilm formation in C. sativus, respectively. Therefore, the present study offered C. sativus as an anti-biofilm formation in S. mutans clinical isolates. In addition, more extensive studies and in vivo research are needed to confirm the results of this study.
کلیدواژه‌ها
Keywords: Tooth Decay؛ Streptococcus mutans؛ Biofilm formation؛ Crocus sativus
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