| تعداد نشریات | 285 |
| تعداد نشریات سازمان | 83 |
| تعداد شمارهها | 3,107 |
| تعداد مقالات | 34,629 |
| تعداد مشاهده مقاله | 49,704,349 |
| تعداد دریافت فایل اصل مقاله | 80,111,003 |
Trend of Changes in the Titer of Antibody against Avian Influenza Virus H9n2 during Raising Period in Vaccinated and Unvaccinated Broiler Farms in Qazvin Province, Iran: A Cohort Study | ||
| Archives of Razi Institute | ||
| مقاله 4، دوره 75، شماره 1، خرداد 2020، صفحه 9-16 اصل مقاله (506.47 K) | ||
| نوع مقاله: Original Articles | ||
| شناسه دیجیتال (DOI): 10.22092/ari.2018.120089.1183 | ||
| نویسندگان | ||
| K. Mirzaie1؛ A. Shoushtari2؛ S. Bokaie* 1؛ M.H. Fallah Mehrabadi2؛ S.M. Peighambari3 | ||
| 1Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran | ||
| 2Department of Poultry Diseases, Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran | ||
| 3Department of Avian Diseases, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran | ||
| چکیده | ||
| Avian influenza virus (AIV) H9N2 is endemic in Iran and its large-scale circulation in the poultry industry of the country is devastating. This virus was first reported in the industrial poultry populations of Iran in July 1998. Some of the published studies showed that inactivated avian influenza (AI) vaccines are capable of inducing an immune response and providing protection against morbidity and mortality in different countries (Vasfi et al., 2002; Tavakkoli et al., 2011). Low pathogenicity avian influenza subtype H9N2 virus has been reported to have a zoonotic potential and widespread distribution in Iran. Therefore, water-in-oil emulsion vaccines are employed to control the disease in chickens (Nili and Asasi, 2003). This cohort study was conducted during July 2016-November 2017 in broiler chicken farms of Qazvin province, Iran to investigate the serological change trends in broiler chickens in this region. Level of immunity against the H9N2 virus was evaluated by hemagglutination inhibition assay. Fifteen farms out of thirty enrolled units used AI H9N2 killed vaccines. The minimum of mean antibody titers (MATs) was 4.54-2.42 and the maximum of MATs was 4.54+2.42 on day 3. In addition, the minimum and maximum MATs on day 50 were 0.4-0.64 and 0.4+0.064, respectively. The transfer rate of H9N2 AIV antibodies from the serum of breeders to the serum of chickens was calculated as 60.35% in our study. A significant difference was revealed between the maternal mean antibody titers (MMATs) and the MATs on day 3 (p <0.001). In addition, the difference between the MATs on day 3 and the MATs on day 10 was found to be significant (p <0.01). Moreover, MATs were significantly different between the vaccinated and unvaccinated herds on day 40 (p <0.05), while no significant difference was observed on days 3, 10, 20, and 30 (P>0.05). According to the results of this study, antibody titers in the vaccinated farms did not reach the protective level until the end of the rearing period. Most of the unvaccinated herds experienced a spurt in antibody titers due to exposure to the virus. Consequently, biosecurity measures must be implemented more seriously and strictly in broiler farms. | ||
| کلیدواژهها | ||
| Antibody titer؛ Broiler farms؛ H9N2 avian influenza virus؛ Iran | ||
| عنوان مقاله [English] | ||
| ارزیابی روند تغییرات تیتر آنتی بادی علیه ویروس آنفلوآنزای پرندگان (تحت تیپ H9N2) درطول دوره پرورش طیور گوشتی واکسینه و غیرواکسینه در استان قزوین، ایران: یک مطالعه کوهورت | ||
|
سایر فایل های مرتبط با مقاله
|
||
| مراجع | ||
|
Alexander, D.J., 2000. A review of avian influenza in different bird species. Vet Microbiol 74, 3-13.
Chen, H., Smith, G.J., Li, K.S., Wang, J., Fan, X.H., Rayner, J.M., et al., 2006. Establishment of multiple sublineages of H5N1 influenza virus in Asia: implications for pandemic control. Proc Natl Acad Sci U S A 103, 2845-2850.
Fallah Mehrabadi, M., Bahonar, A., Tehrani, F., Vasfimarandi, M., Sadrzadeh, A., Ghafouri, S., et al., 2015. Avian influenza H9N2 seroepidemiological survey in rural domestic poultry of Iran. Iran J Epidemiol 10, 1-8.
Fallah Mehrabadi, M.H., Bahonar, A.R., Vasfi Marandi, M., Sadrzadeh, A., Tehrani, F., Salman, M.D., 2016. Sero-survey of Avian Influenza in backyard poultry and wild bird species in Iran-2014. Prev Vet Med 128, 1-5.
Fatima, Z., Khan, M.A., Ahmad, M., Muhammad, K., Khwaja, K.N., Khan, A., et al., 2017. Cross sectional survey of live bird markets, and zoo birds for circulating influenza subtypes in Pakistan. Pak Vet J 37, 185-189.
Gharaibeh, S., Mahmoud, K., Al-Natour, M., 2008. Field evaluation of maternal antibody transfer to a group of pathogens in meat-type chickens. Poult Sci 87, 1550-1555.
Gu, M., Xu, L., Wang, X., Liu, X., 2017. Current situation of H9N2 subtype avian influenza in China. Vet Res 48, 49.
Guan, Y., Shortridge, K.F., Krauss, S., Chin, P.S., Dyrting, K.C., Ellis, T.M., et al., 2000. H9N2 influenza viruses possessing H5N1-like internal genomes continue to circulate in poultry in southeastern China. J Virol 74, 9372-9380.
Guan, Y., Shortridge, K.F., Krauss, S., Webster, R.G., 1999. Molecular characterization of H9N2 influenza viruses: were they the donors of the "internal" genes of H5N1 viruses in Hong Kong? Proc Natl Acad Sci USA 96, 9363-9367.
Guo, Y., Li, J., Cheng, X., 1999. [Discovery of men infected by avian influenza A (H9N2) virus]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 13, 105-108.
Hadipour, M., Golchin, P., 2011. Serosurvey of H9N2 avian influenza virus during respiratory disease outbreaks in broiler flocks in Dezful, southern Iran. Bulg J Vet Med 14, 62-65.
Hadipour, M.M., Habibi, G., Vosoughi, A., 2011. Prevalence of antibodies to H9N2 avian influenza virus in backyard chickens around Maharlou lake in Iran. Pak Vet J 31, 192-194.
Homme, P.J., Easterday, B.C., 1970. Avian influenza virus infections. IV. Response of pheasants, ducks, and geese to influenza A-turkey-Wisconsin-1966 virus. Avian Dis 14, 285-290.
Kimble, J.B., Sorrell, E., Shao, H., Martin, P.L., Perez, D.R., 2011. Compatibility of H9N2 avian influenza surface genes and 2009 pandemic H1N1 internal genes for transmission in the ferret model. Proc Natl Acad Sci U S A 108, 12084-12088.
Lee, C.W., Senne, D.A., Suarez, D.L., 2004. Effect of vaccine use in the evolution of Mexican lineage H5N2 avian influenza virus. J Virol 78, 8372-8381.
Li, X., Shi, J., Guo, J., Deng, G., Zhang, Q., Wang, J., et al., 2014. Genetics, receptor binding property, and transmissibility in mammals of naturally isolated H9N2 Avian Influenza viruses. PLoS Pathog 10, e1004508.
Lupiani, B., Reddy, S.M., 2009. The history of avian influenza. Comp Immunol Microbiol Infect Dis 32, 311-323.
Maas, R., Rosema, S., van Zoelen, D., Venema, S., 2011. Maternal immunity against avian influenza H5N1 in chickens: limited protection and interference with vaccine efficacy. Avian Pathol 40, 87-92.
Mehrabadi, M.H.F., Bahonar, A., Mirzaei, K., Molouki, A., Ghalyanchilangeroudi, A., Ghafouri, S.A., et al., 2018. Prevalence of avian influenza (H9N2) in commercial quail, partridge, and turkey farms in Iran, 2014-2015. Trop Anim Health Prod 50, 677-682.
Nili, H., Asasi, K., 2003. Avian influenza (H9N2) outbreak in Iran. Avian Dis 47, 828-831.
OIE, A., 2016. Manual of diagnostic tests and vaccines for terrestrial animals, Office international des epizooties, Paris, France.
RahimiRad, S., Alizadeh, A., Alizadeh, E., Hosseini, S.M., 2016. The avian influenza H9N2 at avian-human interface: A possible risk for the future pandemics. J Res Med Sci 21, 51-51.
Spackman, E., Senne, D.A., Davison, S., Suarez, D.L., 2003. Sequence analysis of recent H7 avian influenza viruses associated with three different outbreaks in commercial poultry in the United States. J Virol 77, 13399-13402.
Sun, Y., Pu, J., Fan, L., Sun, H., Wang, J., Zhang, Y., et al., 2012. Evaluation of the protective efficacy of a commercial vaccine against different antigenic groups of H9N2 influenza viruses in chickens. Vet Microbiol 156, 193-199.
Swayne, D., Saif, Y., Barnes, H.J., Glisson, J., Fadly, A., McDougald, L., 2013. Diseases of poultry, Blackwell Publishing Ltd, New York.
Swayne, D.E., 2009. Avian influenza vaccines and therapies for poultry. Comp Immunol Microbiol Infect Dis 32, 351-363.
Tavakkoli, H., Asasi, K., Mohammadi, A., 2011. Effectiveness of two H9N2 low pathogenic avian influenza conventional inactivated oil emulsion vaccines on H9N2 viral replication and shedding in broiler chickens. Iran J Vet Res 12, 214-221.
Trampel, D.W., Zhou, E.M., Yoon, K.J., Koehler, K.J., 2006. Detection of antibodies in serum and egg yolk following infection of chickens with an H6N2 avian influenza virus. J Vet Diagn Invest 18, 437-442.
Vasfi, M., Bozorgmehri, F., Hassani, T., Kerdabadi, M., Charkhkar, S., Farahmandi, M., 2000. Serological monitoring of haemagglutination inhibition antibodies in a multi aged layer farm following avian influenza outbreak due to H9N2 sub-serotype in 1998 in Iran. J Facul Vet Med Univ Tehran 55, 73-81.
Vasfi, M.M., Bozorg, M.M., Hashemzadeh, M., 2002. Efficacy of inactivated H9N2 avian influenza vaccine against non-highly pathogenic A/Chicken/Iran/ZMT-173/1999 infection. Arch Razi Institute 53, 23-32.
Zhang, A., Lai, H., Xu, J., Huang, W., Liu, Y., Zhao, D., et al., 2017. Evaluation of the Protective Efficacy of Poly I:C as an Adjuvant for H9N2 Subtype Avian Influenza Inactivated Vaccine and Its Mechanism of Action in Ducks. PLoS One 12, e0170681 | ||
|
آمار تعداد مشاهده مقاله: 2,190 تعداد دریافت فایل اصل مقاله: 2,996 |
||
