| تعداد نشریات | 284 |
| تعداد نشریات سازمان | 82 |
| تعداد شماره‌ها | 3,069 |
| تعداد مقالات | 34,253 |
| تعداد مشاهده مقاله | 47,028,608 |
| تعداد دریافت فایل اصل مقاله | 77,956,456 |
Potential Protective Effect of Pretreatment with Caraway Essential Oil in vivo Model of Iron Nanoparticle-induced Liver Injury | ||
| Journal of Medicinal plants and By-products | ||
| مقاله 3، دوره 7، شماره 2، آذر 2018، صفحه 145-152 اصل مقاله (204.58 K) | ||
| شناسه دیجیتال (DOI): 10.22092/jmpb.2018.118142 | ||
| نویسندگان | ||
| Abolfazl Dadkhah* 1؛ Faezeh Fatemi2؛ Mohammad Reza Mohammadi Malayeri3؛ Fatemeh Torabi4؛ Mostafa Sarbazi5؛ Salome Dini6 | ||
| 1Department of Medicine, Faculty of Medicine, Qom Branch, Islamic Azad University, Qom, Iran | ||
| 2Materials and Nuclear Fuel Research School, Nuclear Science and Technology Research Institute, Tehran, Iran | ||
| 3Department of Pathobiology, Faculty of Veterinary Medicine, Garmsar Branch, Islamic Azad University, Garmsar-Iran. | ||
| 4Department of Physiology, Faculty of Science, Qom Branch, Islamic Azad University, Qom, I.R. Iran | ||
| 5Graduated Student, Faculty of Veterinary Medicine, Garmsar Branch, Islamic Azad University, Garmsar-Iran | ||
| 6Young Researchers and Elite Club, Karaj Branch, Islamic Azad University, Karaj, Iran | ||
| چکیده | ||
| Recently, there has been a great deal of interest in the use of the medicinal plants with high antioxidant compounds for curing liver injuries induced by hepatoxcitic agents. This study was to assess the protective effect of Carum carvi L. essential oil (E.O) on the hepatoxitic rats induced by overdose of iron oxide nanoparticles (NPs). The rats were distributed to 4 groups. In negative control group (NC), the rats received normal saline and DMSO daily for 3 days. In control group (C), iron oxide nanoparticles (Fe2O3) (200 mg/kg b.w) was injected daily for 3 days. In the treatment groups, iron oxide nanoparticles plus E.O at 100 & 200 mg/kg b.w were injected daily for 3 days. In following, cytochrome P450 (CYP450), glutathione S-transferase (GST), glutathione (GSH), aspartate transaminase (AST), alkaline phosphatase (ALP) and alanine transaminase (ALT) were estimated at 72 h after NP-treatment. The administration of the E.O could return considerably the decrease of the GST and GSH levels as well as the increase of the level of AST induced by iron oxide NPs. These results are in agreement with histopathological results. The data indicated that E.O provided an efficient prevention against iron oxide NPs-induced hepatotoxicity in rats. | ||
| کلیدواژه‌ها | ||
| Carum carvi؛ essential oil؛ Iron oxide nanoparticles؛ Liver enzymes؛ Detoxification enzymes؛ Hepatotoxicity | ||
| مراجع | ||
|
1. Pandit A, Sachdeva T, Bafna P. Drug-Induced Hepatotoxicity: A Review. J Appl Pharm Sci. 2012;2: 233-243.
2. Lome MC, Thompson RP, Powell JJ. Fine and ultrafine particles of the diet: influence on the mucosal immune response and association with Crohn’s disease. Proc Nutr Soc. 2002;61:123-130.
3. Babadi VY, Najafi L, Najafi A, Gholami H, Beigi Zarji ME, Golzadeh J. Evaluation of iron oxide nanoparticles effects on tissue and enzymes of liver in rats. Elixir Appl Chem. 2013;55A:13226-13229.
4. Wang J, Pantopoulos K. Regulation of Cellular Iron Metabolism. Biochem J. 2011; 434: 365-381.
5. Najafzadeh H, Razi Jalali M, Morovvati H, Taravati F. Comparison of the Prophylactic Effect of Silymarin and Deferoxamine on Iron Overload-Induced Hepatotoxicity in Rat. J Med Toxicol. 2010;6:22-26.
6. Handy RD, Shaw BJ. Toxic effects of nanoparticles and nanomaterials: Implications for public health, risk assessment and the public perception of nanotechnology. Health Risk & Society. 2007;9:125-144.
Password~0
7. Plank C, Scherer F, Schillinger U, Bergemann C, Anton M. Magnetofection: enhancing and targeting gene delivery with superparamagnetic nanoparticles and magnetic fields. J Liposome Res.2003;13:29-32.
8. Stone V, Johnston H, Clift MJD. Air pollution, ultrafine and nanoparticle toxicology: Cellular and molecular interactions. IEEE Trans Nanobioscience. 2007;6:331-40. 9. Arefian Z, Pishbin F, Negahdary M, Ajdary M. Potential toxic effects of Zirconia Oxide nanoparticles on liver and kidney factors. Biomed Res. 2015;26:89-97. 10. Agrahari P, Singh DK. A review on the pharmacological aspects of Carum carvi L. J Biol Earth Sci. 2014;4:M1-M1 3.
11. Eddouks M, Lemhadri A, Michel J. Caraway and caper: potential anti-hyperglycaemic plants in diabetic rats. J Ethnopharmacol. 2004;94:143-148.
12. Madisch, A, Holtmann G, Mayr G, Vinson B, Hotz J. Treatment of functional dyspepsia with a herbal preparation. Digestion. 2004;69:45- 52.
13. Leporatti ML, Ghedira K. Comparative analysis of medicinal plants used in traditional medicine in Italy and Tunisia. J Ethnobiol Ethnomed. 2009;5:31-9.
14. Csedő K. Medicinal Plants from Harghita County (in Hungarian) UJCOOP Tipografia Tg Mureş. 1980; 188- 194.
15. Zargary A. Medicinal Plants. 5 th ed. Tehran: Tehran University Publications; 2001.
16. Seidler-Łożykowska K, Kędzia B, Karpińska E, Bocianowski J. Microbiological activity of caraway (Carum carvi L.) essential oil obtained from different origin. Acta Scientiarum Agronomy. 2013;35:495-500.
17. Grigore A, Colceru-Mihul S, Paraschi I, Nița S, Christof R, et al. Chemical analysis and antimicrobial activity of indigenous medicinal species volatile oils. Romanian Biotech Lett. 2012; 17: 7620-7627.
18. Haggag EG, Abou-Moustafa MA, Boucher W, Theoharides TC. The effect of a herbal water extract on histamine release from mast cells and on allergic asthma. J Herbal Pharmacother. 2003;3:41-54.
19. Baananou S, Bagdonaite E, Marongiu B, Piras A, Porcedda S, et al. Extraction of the volatile oil from Carum carvi of Tunisia and Lithuania by supercritical carbon dioxide: Chemical composition and antiulcerogenic activity. Nat Prod Res. 2013; 27:2132-2136.
20. Mariutti LRB, Barreto GPM, Bragagnolo N, Mercadante AZ. Free radical scavenging activity of ethanolic extracts from herbs and spices commercialized in Brazil. Braz Arch Biol Technol. 2008;51:1225-1232.
21. Samojlik I, Lakić N, Mimica-Dukić N, Daković-Svajcer K, Bozin B. Antioxidant and hepato protective potential of essential oils of coriander (Coriandrum sativum L.) and caraway (Carum carvi L.) (Apiaceae). J Agric Food Chem. 2010; 58: 8848-8853.
22. Johri RK. Cuminum cyminum and Carum carvi: An update. Pharmacogn Rev. 2011;5:63-72.
23. Fatemi F, Allameh A, Khalafi H, Rajaee R, Rezaei MB. Biochemical properties of γ-irradiated caraway essential oils. J Food Bio chem. 2011;35:650-62.
24. Dadkhah A, Fatemi F. Heart and kidney oxidative stress status in septic rats treated with caraway extracts. Pharm Biol. 2011; 49: 679-686.
25. Dadkhah A, Allameh A, Khalafi H, Ashrafihelan J. Inhibitory Effects of Dietary Caraway Essential Oils on 1, 2-Dimethylhydrazine-Induced Colon Carcinogenesis is Mediated by Liver Xenobiotic Metabolizing Enzymes. Nutrition and Cancer. 2011; 63:46-54.
26. Habig WH, Pabst MJ, Jakoby WB. Glutathione S-transferases: the first enzymatic step in mercapturic acid formation. J Biol Chem. 1974; 25:7130-7139.
27. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein- dye binding. Anal Biochem. 1976; 72: 248-54.
28. Seldak J, Lindsay RH. Estimation of Total Protein Bound and Non-Protein Sulfidryl Groups in Tissue with Elman, s Reagent. Anal Biochem. 1968; 25:192-205.
29. Lillie RD. Histopathologic technic and practical histochemistry, 3rd ed. New York: McGraw-Hill Book Co. 1965. 407p.
30. Eidi A, Eidi M, Al-Ebrahim M, Rohani AH, Mortazavi P. Protective effects of sodium molybdate on carbon tetrachloride-induced hepatotoxicity in rats. J Trace Elem Med Biol. 2011; 25(1): 67-71.
31.Rasooli A, Fatemi F, Akbarzadeh K, Dini S, Bahremand S. Synergistic Protective Activity of Deuterium Depleted Water (DDW) and Satureja rechingeri Essential Oil on Hepatic Oxidative Injuries Induced by Acetaminophen in Rats, Journal of Essential Oil Bearing Plants, 2016;19: 1086- 1101.
32. Dadkhah A, Fatemi F, Ababzadeh S, Roshanaei K, Alipour M, et al. Potential preventive role of Iranian Achillea wilhelmsii C. Koch essential oils in acetaminopheninduced hepatotoxicity. Botanical Studies. 2014a;55:37.
33. Dadkhah A, Fatemi F, Malayeri M, Jahanbani A, Batebi F, Ghorbanpour Z. The Chemo-preventive Effect of Nigella Sativa on 1, 2-dimethylhydrazine-induced Colon Tumor. Indian ijper. 2014b; 48:39-48.
34. Dadkhah A, Fatemi F, Ababzadeh S, Roshanaei K, Alipour M, Sadegh Tabrizi B. Potential preventive role of Iranian Achillea wilhelmsii C. Koch essential oils in acetaminophen-induced hepa-totoxicity. Botanical Studies .2014c; 55: 37.
35. Dadkhah A, Fatemi F, Eslami Farsani M, Roshanaei K, Alipour M, et al. Hepatoprotective Effects of Iranian Hypericum scabrum Essential Oils Against Oxidative Stress Induced by Acetaminophen in Rats. Braz Arch Biol Technol. 2014d; 57:340-348.
36. Attaran HA, Dini S, Fatemi F, Hesaraki S, Parhizkarie M, Dadkhaha A. Hepatoprotective Evaluation of Iranian Satureja Rechingeri Essential Oils against Oxidative Injuries Induced by Acetaminophen in Wistar Rats. Int. J. Rev. Life. Sci. 2015; 5:204-210. 37. Fatemi F, Allameh A, Khalafi H, Ashrafihelan J. Hepatoprotective effects of gamma-irradiated caraway essential oils in experimental sepsis. Appl Radiat Isot. 2010a; 68:280-5.
38. Fatemi F, Allameh A, Khalafi H, Rezaei MB. Seyhoon, M. The effect of essential oils and hydroalcoholic extract of caraway seed on oxidative stress parameters in rats suffering from acute lung inflammation before and after γ-irradiation. J Med Aroma Plant. 2010b; 25:441-455.
39. Paradies G, Petrosillo G, Paradies V, Ruggiero FM. Mitochondrial dysfunction in brain aging: role of oxidative stress and cardiolipin. Neurochem. Int. 2011; 58: 447-457.
40. Hutchison TA, Shahan DR, Anderson ML. (eds.): Drugdex System. Englewood, CO; Micromedex Inc. Expires: December. 2000.
41. Sally A, Tice RP, H Dean Parry RPh. Medications that need hepatic Monitoring. Hospital Pharmacy. 2001; 36: 456-464.
42. Limdi JK, HydeGM. Evaluation of abnormal liver function tests. Postgrad Med J. 2003; 79: 307-312.
43. Shirband A, Azizian H, Pourentezari M, Rezvani ME, Anvari M, et al. Dose-dependent Effects of Iron Oxide Nanoparticles on Thyroid Hormone Concentrations in Liver Enzymes: Possible Tissue Destruction. GJMRS. 2014; 1:28-31.
44. Ghasempour S, Shokrgozar MA, Ghasempour R, Alipour M. The acute toxicity of urea coated ferrous oxide nanoparticles on L929 cell line, evaluation of biochemical and pathological parameters in rat kidney and liver. Physiol Pharmacol. 2014; 17:423-436.
45. Jensen PD, Jensen FT, Christensen T, Nielsen JL, Ellegaard J. Relationship between hepatocellular injury and transfusional iron overload prior to and during iron chelation with desferrioxamine: a study in adult patients with acquired anemias. Blood. 2003; 101(1): 91-96.
46. Lijuan W, Lin W, Wenjun D, Fang Z. Acute Toxicity of Ferric Oxide and Zinc Oxide Nanoparticles in Rats. J N N. 2010; 10 (12): 8617-8624.
47. De S, Ravishankar B, Bhavsar GC. Plants with hepatoprotective activity: A review. Ind Drugs. 1993;30: 355.
48. Khopde SM, Indira Priyadarsini K, Mohan h, Gawandi VB, Satav JG, et al. Characterizing the antioxidant activity of amla (Phyllanthus emblica) extract. Curr Sci. 2001; 81:185.
49. Dadkhah A, Khalafi H, Rajaee R, Allameh A, Rezaei MB, et al. Study of the effects of gamma-irradiation on microbial load and efficient extracts of caraway seeds. J Nuclear Sci Tech. 2009; 49: 27-34.
50. Najda A, Dyduch J, Brzozowski N. Flavonoid content and antioxidant activity of caraway roots (Carum carvi L.). Veg Crops Res Bull. 2008; 68:27-133.
51. Krishnakantha TP, Lokesh BR. Scavenging of superoxide anions by spice principles. Indian J Biochem Biophys. 1993; 30:133-4.
52. Faleiro L1, Miguel G, Gomes S, Costa L, Venâncio F, Teixeira A, Figueiredo AC, Barroso JG, Pedro LG.Antibacterial and antioxidant activities of essential oils isolated from Thymbra capitata L. (Cav.) and Origanum vulgare L. J Agric Food Chem. 2005; 53:8162-8. | ||
|
آمار تعداد مشاهده مقاله: 807 تعداد دریافت فایل اصل مقاله: 592 |
||