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مطالعه پویش کل ژنومی صفات ترکیبات لاشه در جمعیت F2 حاصل از تلاقی مرغ بومی آذربایجان غربی وسویه گوشتی آرین | ||
| علوم دامی | ||
| مقاله 19، دوره 30، شماره 116، آذر 1396، صفحه 231-246 اصل مقاله (1.24 M) | ||
| نوع مقاله: مقاله پژوهشی | ||
| شناسه دیجیتال (DOI): 10.22092/asj.2017.110171.1434 | ||
| نویسندگان | ||
| علی جوانروح علی آباد* 1؛ رسول واعظ ترشیزی2؛ علی اکبر مسعودی3؛ علیرضا احسانی3 | ||
| 1دانش آموخته دکتری، گروه علوم دامی، دانشکده کشاورزی، دانشگاه تربیت مدرس، تهران، ایران | ||
| 2دانشیار گروه علوم دامی، دانشکده کشاورزی، دانشگاه تربیت مدرس، تهران. | ||
| 3استادیار، گروه علوم دامی، دانشکده کشاورزی، دانشگاه تربیت مدرس، تهران، ایران | ||
| چکیده | ||
| ترکیبات لاشه جزء صفات مهم اقتصادی در جوجه های گوشتی محسوب می شود. به منظور شناسایی جایگاهها و ژنهای مرتبط با صفات ترکیبات لاشه، مطالعه پویش کل ژنوم(GWAS) با استفاده از یک تراشه SNP ژنوم مرغ (SNP Beadchip (Illumnia 60k Chicken در یک جمعیت F2 حاصل از تلاقی دوطرفه مرغ بومی آذربایجان غربی و خط B سویه گوشتی آرین انجام شد. برای هر پرنده، صفات وزن لاشه، وزن سینه و وزن ران و درصدهای مربوطه مورد اندازه گیری قرار گرفت. با استفاده از دو مدل GLM و CMLM ارتباط هر یک SNP ها با این صفات مورد بررسی قرار گرفت. در مجموع تعداد 22 نشانگر SNP برای صفات ترکیبات لاشه شناسایی شد. این نشانگرهای SNP شناسایی‌شده در داخل، ناحیه بالادست و یا در ناحیه پایین‌دست ژنهای کاندیدا قرار‌داشتند. ژنهای کاندیدای شناسایی‌شده عملکرد مولکولی مرتبط با هر یک از صفات مورد مطالعه را داشتند و لذا می‌توان از این ژنهای کاندیدا در برنامه‌های اصلاحی طیور مورد استفاده قرار‌داد. | ||
| کلیدواژه‌ها | ||
| مرغ؛ جمعیت F2؛ صفات ترکیبات لاشه؛ مطالعه پویش کل ژنومی؛ ژنهای کاندیدا | ||
| عنوان مقاله [English] | ||
| Genome wide association study(GWAS) for body composition traits in a F2 population crosses of Arian broiler line and Azerbaijan native chicken | ||
| نویسندگان [English] | ||
| Ali javanrouh1؛ R. Vaez Torshizi2؛ Ali akbar Masoudi3؛ alireza ehsani3 | ||
| 1member of science | ||
| 2Associated Professor, Department of Animal Science, Faculty of Agriculture, Tarbiat Modares university, Tehran, Iran | ||
| 3Associated Professor, Department of Animal Science, Faculty of Agriculture, Tarbiat Modares university, Tehran, Iran | ||
| چکیده [English] | ||
| Body compositions in broiler are important economic traits. In order to identify loci associated with body composition traits, genome-wide association study (GWAS) was carried out in a chicken F2 population, derived from a reciprocal cross between Azerbaijan indigenous chickens and Aryan broiler line using Illumina 60K Chicken SNP Beadchip. For each bird, a total 6 traits including carcass weight, breast weight, drumstick and thigh weight and their percentage traits were recorded. The association between the identified SNPs and body composition traits was estimated by general linear model (GLM) and compressed mixed linear model (CMLM). A total of 22 SNPs were found in the genome-wide significance and suggestive levels. All detected SNPs were located in internal, upstream and/or downstream of candidate genes related to our studied traits. In conclusion, the identified candidate genes have molecular functions related to body composition traits. So, these candidate genes can be applied in the chicken breeding scheme. | ||
| کلیدواژه‌ها [English] | ||
| Chicken, F2 population, body composition traits, GWAS, Candidate genes | ||
| مراجع | ||
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