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Ecological Requirement, Ethnopharmacology, Phytochemical and Antioxidant Capacity of Vaccinium arctostaphylos L. in Gilan Province (North of Iran) | ||
| Journal of Medicinal plants and By-Products | ||
| مقاله 12، دوره 5، شماره 1، تیر 2016، صفحه 89-95 اصل مقاله (841.2 K) | ||
| شناسه دیجیتال (DOI): 10.22092/jmpb.2016.108928 | ||
| نویسندگان | ||
| Azad Khalili Musavi* 1؛ Masoumeh Mazandarani2؛ Suzan Rahimian3؛ Mohammad Ghafourian4 | ||
| 1Department of Botany, Astara Branch, Islamic Azad University, Astara, Iran | ||
| 2Department of Botany, Gorgan Branch, Islamic Azad University, Gorgan, Iran | ||
| 3Department of Agricultur, Astara Branch, Islamic Azad University, Astara, Iran | ||
| 4Department of Medical, Mazandaran University of Medical Sciences, Ramsar, Iran | ||
| چکیده | ||
| This study is investigate to ecological characters, ethnopharmacology, total phenols (TP), flavonoids (TF), anthocyanins (TA) contentand antioxidant capacity in leaves and fruit of Vaccinium arctostaphylos L. from two natural habitats from Gilan provinve, which has been used as a heart tonic ,anti diabeteand anti tumor. Ecological requirements were obtained in many field observation, ethno pharmacological survey was carried out among the well known indigenous herbal practitioners (60-78 ages) in South west of Gilan. The leaves and fruits of Vaccinium arctostaphylos L. were collected from two natural habitats (Khotbe sara,1600 m and Asalem, 1300 m) during Sep to Oct 2013, respectively. Methanol extracts were obtained by maceration, TP, TF and TA were determined by spectro photometrically, antioxidant capacity were measured by total antioxidant capacity (TAC), reducing power (RP) and 2,2-Diphenyl-1-picrylhydrazyl (DPPH) in compare of BHT and BHA antioxidant standard and Quersetin content was messured by HPLC method. Results were showed that Vaccinium arctostaphylos L. is usually wild grow in silty loam soils (1300-1600m) and its fruit was appeared from June to September .In both regions phenolic components had significant variation, ranging from TP content(263.17-471.26 mg GAEg-1),TF(186.18-289.17 mg QUE g-1) , TA (74.3- 145.29 mg CydEg-1 ) and quersetin content (136.13-218.2 ppm respectively in 1300-1600m. Generally the fruits extract especially in 1600m had more source of phenolic componds, so was showed better antioxidant capacity (IC50 value 2.98±0.51 µg/ml) to will be confirmed the traditional uses of plant in these regions as an good anti-inflammatory and anti diabetic. | ||
| کلیدواژه‌ها | ||
| Antioxidant؛ Autecology؛ Ethnopharmacology؛ TP؛ TF؛ TA؛ Gilan؛ Vaccinium arctostaphylos L | ||
| مراجع | ||
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1. Yuan W, Zhou L, Deng G, Wang P, Creech D, Li SH. Anthocyanins, phenolics and antioxidant capacity of Vaccinium L. in Texas USA. Pharm crops J. 2011;2,:11-23.
2. Wang SY, Chen CT, Sciarappa W. Fruit quality, antioxidant capacity, and flavonoid content of organically and conventionally grown blueberries. Agric food chem. J, 2008;56:5788-94.
3. Ho KY, Tsai CC, Huang J S, Chen CP, Lin TC, LinCC. Antimicrobial activity of tannin components from Vaccinium vitis-idaea L. Journal of Pharmacol. 2012;53:187-191.
4. Faria A, Pestana D, Teixeira D, de Freitas V, Mateus N, Calhau C. Blueberry anthocyanins and pyruvic acid adducts: anticancer properties in breast cancer cell lines. Phyto chem. Res J. 2010;64:168-172.
5. MannalP,McDonald D, McFadden D. Pterostilbene and tamoxifen show an additive effect against breast cancer in vitro. J. gastrointeturg. 2010;14:873-9.
6. Paul S, DeCastro AJ, Lee HJ. Dietary intake of pterostilbene, a constituent of blueberries, inhibits the beta-catenin/p65 downstream signaling pathway and colon carcinogenesis in rats. Carcinogen J .2010;31:1272-8.
7. Stoner GD, Want LS, SeguinC. Multiple berry types prevent N-nitrosom ethylbenzylamine-induced esophageal cancer in rats. Pharm Res J. 2010;27:1138-1145.
8. Adams LS, Phung S, Yee N. Blueberry phytochemicals inhibit growth and metastatic potential of MDA-MB-231 breast cancer cells through modulation of the phosphatidylinositol 3-kinase pathway. Cancer Res J .2010;70:3594-3605.
9. Braga PC, Antonacci R, WangYY, Lattuada N, Dal SassoM, Marabini L, Fibiani F, Lo Scalzo R. Comparative antioxidant activity of cultivated and wild Vaccinium species investigated by EPR, human neutrophil burst and COMET assay. Eurrev med pharmacol Sci J. 2013;17:1987-1999.
10. Basu A, Rhone M, Lyons TJ. Berries: emerging impact on cardiovascular health. Nutrrev J. 2010;68:168-77. Review.
11. Zheng Y, WangCY, Shiow Y, WangA, ZhengW. Effect of high-oxygen atmospheres on blueberry phenolics, anthocyanins, and antioxidant capacity. Agric and food chem. J. 2003;51:7162-7169.
12. Pourmorad F, Hosseinimehr SJ, Shahabimajd N. Antioxidant activity, phenol and flavonoid contents of some selected Iranian medicinal plants. Afr journal of Biotech. 2006;5:1142-1145.
13. Arabshahi-Delou S, Urooj A. Antioxidant properties of various solvent extracts of mulberry (Morus indica L.) leaves. Food chem. 2007;102:1233-40.
14. Giusti MM, Wrolstad RE. Characterization and measurement of anthocyanins by UV-visible spectroscopy. In: Current Protocols Food chem. 2001;3:1-13.
15. Dragovi-Uzelac V, ZvonimirS, BralaA, Levaj B. Evaluation of phenolic content and antioxidant capacity of blueberry cultivars (Vaccinium corymbosum L.) grown in the north west Croatia. Food tech biotech J. 2010; 48:214-221.
16. Mazandarani M, Majidi Z, Zarghami-Moghaddam P. Essential oil composition, total phenol, flavonoid, anthocyanin and antioxidant activities in different parts of Artemisia annua L. in two localities (North of Iran). J of Med Plants & By-products. 2010;1:13-21.
17. Mazandarani M, Makari S, Bajian GR. Evaluation of phytochemical and antioxidant activity in different parts of Heracleum gorganicum Rech.F. in Golestan province, North of Iran. Iranian J Plant Physiology. 2010; 2:381-388.
18. Mazandarani M, ZarghamiMoghaddam P, ZolfaghariMR. Effects of solvent type on phenolics and flavonoids content and antioxidant activities in Onosma dichroanthum Boiss. J Med Plants Res. 2012; 6:4481-4488.
19. Grace MH, David M, Ribnicky DM, Kuhn P, PoulevA, Logendra S, Yousef GG , RaskinI, LilaMA. Hypoglycemic activity of a novel anthocyanin-rich formulation from lowbush blueberry, Vaccinium angustifolium . Phytomedicine J. 2009;16:406-415.
20. Cory S, Harris A, Burt J, Saleem A, Mai P, Louis L, Martineau C, Pierre S. A single HPLC-PAD-APCI/MS method for the quantitative comparison of phenolic compounds found in leaf, stem, root and fruit extracts of Vaccinium angustifolium. Phytomedicine. Phyto Chem Analysis. 2007;18:161-169 .
21. Eid HM, Martineau LC, Saleem A, Asim MuhammadD, VallerandA, BenhaddouA, Lidia Nistor A, Arvind Afshar B, John T, Arnason PM, Ierre S. Stimulation of AMP-activated protein kinase and enhancement of basal glucose uptake in muscle cells by quercetin and quercetin glycosides, active principles of the antidiabetic medicinal plant Vacciniumvitis-idaea. Molecular Nutrition & Food Res J. 2010;54 : 991-1003.
22. Martineau LC, Couture A, Spoor D. Anti-diabetic properties of the Canadian lowbush blueberry Vaccinium angustifolium. Inter National J of Phytomedicine. 2006;13:612-623.
23. Heim KC, Anger SP, Le´onhart S, Ritz BW. Anti-inflammatory and neuro active properties of selected fruit extracts. J Med Food. 2012;15:851-854.
24. Riso P, Klimis-Zacas D, Del Bo C, Martini D, Campolo J, Vendrame S. Effect of a wild blueberry (Vaccinium angustifolium) drink intervention on markers of oxidative stress, inflammation and endothelial function in humans with cardiovascular risk factors. Eur J Nutr Journal. 2012;2:345-349.
25. Jenkins DJA, Ssrichaikul K, Kendall WC. The relation of low glycaemic index fruit consumption to glycaemic control and risk factors for coronary heart disease in type 2 diabetes. Diabetologia J. 2011;54:271-279.
26. Pervin M, Abulhasnat MD, Beongou L. Antibacterial and antioxidant activities of Vaccinium corymbosum L. leaf extract. Asian Pacific J Tropical Disease. 2013;3:444-453.
27. Zarghami Moghaddam P, Mazandarani M, Zolfaghari MR. Antibacterial and antioxidant activities of root extract of Onosma dichroanthum Boiss. in north of Iran. African Microb Res J. 2012;6:1776-1781. | ||
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