| تعداد نشریات | 284 |
| تعداد نشریات سازمان | 82 |
| تعداد شماره‌ها | 3,044 |
| تعداد مقالات | 34,047 |
| تعداد مشاهده مقاله | 46,439,759 |
| تعداد دریافت فایل اصل مقاله | 77,507,594 |
Total Flavonoids Contents and Anti Bacterial Activity of the Extracts of two Labiateae Species: Nepeta menthoides and Thymus trautvetteri | ||
| Journal of Medicinal plants and By-products | ||
| مقاله 11، دوره 4، شماره 1، تیر 2015، صفحه 77-82 اصل مقاله (101.5 K) | ||
| شناسه دیجیتال (DOI): 10.22092/jmpb.2015.108894 | ||
| نویسندگان | ||
| Shadi Ghandchi؛ Mina Jamzad* | ||
| Department of Chemistry, Shahr-e-Qods Branch, Islamic Azad University,Tehran, Iran | ||
| چکیده | ||
| Total flavonoids contents and antibacterial activity of the extracts from the aerial parts of two Labiateae species, Nepeta menthoides Boiss. & Buhse and Thymus trautvetteri Klokov & Desj.-Shost. were determined. Quantitative determination of flavonoid contents was calculated in terms of quercetin equivalent in various extracts (50% methanol, chloroform and distilled water) by AlCl3 colorimetric method. It was found that total flavonoids contents of N. menthoides extracts in different solvents were (2.308%, 0.884% and 0.710%) mg/g and (2.076%, 1.468% and 1.412%) mg/g for T. trautvetteri respectively.Antibacterial activity of the extracts was also determined against 6 gr (+/-) bacteria by disc diffusion method. The results showed that 50% methanol extracts of two species displayed better inhibitor activity against the tested bacteria. The bacteria Stapylococcus epidermidis, Staphylococcus saprophyticus and Staphylococcus aureus were sensitive against 50% methanol extract of N. menthoides even more than the standard antibiotics (10μg). Therefore a good correlation between total flavonoids contents and antibacterial activity of the studied extracts is demonstrated. | ||
| کلیدواژه‌ها | ||
| Nepeta menthoides؛ Thymus trautvetteri؛ Flavonoids contents؛ Antibacterial activity | ||
| مراجع | ||
|
1. Zargari A. Medicinal Plants. Vol.3, 6th ed. Tehran University Publication, Tehran, 1996.
2. Mohammadi A, Malek F, Dehpour A, Nazari H. Chemical composition and antibacterial activity of the essential oils of some medicinal plants. Afr. J. Agric. Res. 2013;8:3151-3158.
3. Kohkonen MP, Hopia AL, Vuorela JH, Rauha JP, Pihlaja K, Kujala TS, Heinonen M. Antioxidant activity of plant extracts containing phenolic compounds. J. Agric. Food Chem. 1999;47:3954-3962.
4. De Sousa RR, Queiroz KC, Souza AC, Gurgueira SA, Augusto AC, Miranda MA, Peppelenbosch MP, Ferreira CV, Aoyama H. Phosphoprotein levels, MAPK activities and NF kappa B expression are affected by fisetin. J. Enzyme Inhib. Med. Chem. 2007;22:439-444.
5. Tereschuk ML, Riera MV, Castro GR, Abdala LR. Antimicrobial activity of flavonoids from leaves of Tagetes minuta. J. Ethnopharmacol. 1997;56:227-232.
6. Aladesanmi AJ, Sofowora A, Leary JD. Preliminary, biological and phytochemical investigation of two Nigerian medicinal plants. Int . J. Crude Drug Res. 1986;24:147-153.
7. Al-Saleh FS, Gamal El-Din AY, Abbas JA, Saeed NA. Phytochemical and biological studies of medicinal plants in Bahrain: Family Chenopodiaceae. part 2. Int J. Pharmacogn. 1997;35:38-42.
8. Mahamoud MJ, Jawad AL, Hussain, AM, AL-Omari M, AL- Naib A. IN vitro antimicrobial activity of Salsola rosmarinus and Adiantum capillus-veneris. Int. J. Crude Drug. Res. 1989;27:14-16.
9. Quarenghi MV, Tereschuk ML, Baigori MD, Abdala LR. Antimicrobial activity of flowers from Anthemis Cotula. Fitoterapia. 2000;71:710-712.
10. Rauha JP, Remes S, Heinonen M, Hopia A, Kähkönen M, Kujala T, Pihlaja K, Vuorela H,Vuorela P. Antimicrobial effects of Finnish plant extracts containing flavonoids and other phenolic compounds. Int. J. Food Microbial. 2000;56:3-12.
11. Singh RK, Nath G. Antimicribial activity of Elaeocarpus sphaericus. Phytother. Res. 1999;13:448-550.
12. Tarle D, Dvorzak I. Antimicrobial activity of the plant Crisium oleraceum (L.). Scop. Acta Pharm. Jugosl. 1990;40:569-571.
13. Torrengra RD, Ricardo AA, Pedrozo JP, Fuentes OC. Flavonoids from Gnaphalium gracile H.B.K. Int. J. Crude Drug Res. 1989;27:22-24.
14. Rechinger KH. Nepeta. In: Rechinger KH (ed.) Flora Iranica. No.150. Akademische Druck and Vertagsanstatt. Graz, Austria, 1982,108.
15. Jamzad Z, Grayer RJ, Kite GC, Simmonds MSJ, Ingrouille M. Leaf surface flavonoids in Iranian species of Nepeta L. (lamiaceae) and some related genera. Biochem. Syst. Ecol. 2003;31:587-600.
16. Bourrel C, Perineau F, Michel G, Bessiere JM. Catnip (Nepeta cataria l) essential oil: analysis of chemical constituents. Bacteriostatic and fungistatic properties. J. Essent Oil Res. 1993;5: 159-167.
17. Jalas J. Thymus. In: Rechinger KH. (ed.) Flora Iranica No. 150. Akademische Druck and Vertagsantsatt,Graz, Austria, 1982, 532.
18. Sattar A, Bankova V, Kujumgiev A, Galabov A, Ignatova A, Todorova C, Popv S. Chemical composition and biological activity of leaf exudates from some Lamiaceae plants. Pharmacie. 1995;50:62-65.
19. Chang CC, Yang MH, Wen HM, Chern JC. Estimation of total flavonoid content in propolis by two complementary colorimetric methods. J. Food Drug Anal. 2002;10:178-182.
20. Bauer AW, Kirby WMM, Sherris JC, Truch M. Antibiotic susceptibility testing by a standardized single disk method. Am. J. Clin. Pathol. 1966;45:493-496.
21. Tepe B, Daferera B, Tepe A, Polissiou M, Sokmen A. Antioxidant activity of the essential oil and various extracts of Nepeta flavida Hub.-Mor. From Turkey. Food Chem. 2007;103:1358-1364.
22. Modincki D, Tokar M, Klimek B. Flavonoids and phenolic acids of Nepeta cataria L. Var. citrodora (Becker) Balb. (Lamiaceae). Acta Pol. Pharm. 2007;64:247-250.
23. Adiguzel A, Ozer H, Sokmen M, Gulluce M, Sokmen A, Kilic H, Sahin F, Bans O. Antimicribial and antioxidant activity of the essential oil and methanol extract of Nepeta cataria. Polish J. Microbiol. 2009;58:69-76.
24. Cigremis Y, Ulukanliz Z, Ilcim A, Akgoz M. In vitro antioxidant and antimicrobial assays of acetone extracts from Nepeta meyeri Bentham. Eur. Rev. Med. Pharmacol. Sci. 2010;14:661-8.
25. Kraujalis P, Venskutonis PR, Ragazinskiene O. Antioxidant activities and phenolic composition of extracts from Nepeta plant species. Food Balt. 2011;79-81.
26. Ozbek Yazici S, Ozmen I, Celikoglu U, Ozcelik H, Genc H. In vitro Antioxidant activities of extracts from some Nepeta species. Int. J. Health & Nutri. 2012;3:8-12.
27. Amzad Hossain M, Salim Al-Raqmi KA, Hamed Al-Mijizi Z, Mohammed Weli A, Al-Riyahi Q. Study of total phenol, flavonoids contents and phytochemical screening of various leaves crude extracts of locally grown Thymus vulgaris. Asian Pac. J. Trop. Biomed. 2013; 3(9): 705-710.
28. Seladji M, bekhechi C, Beddou F, Dib H, Bendimerad N. Antioxidant activity and Phytochemical screening of Nepeta nepetella aqueous and methanolic extracts from Algeria. J. Appl. Pharmacol. Sci. 2014;4:12-16.
29. Dulger B, Gonuz A. Antimicrobial activity of some Turkish medicinal plants. J. Pak. J. Biol. Sci. 2004;7:1559-1562.
30. Parekh J, Chanda SV. In vitro antimicrobial activity and phytochemical analysis of some Indian medicinal plants. Turk. J. Biol. 2007;31:53-58.
31. Al-Bayati FA. Synergistic antibacterial activity between Thymus vulgaris and Primpinella anisum essential oils and methanolic extracts. J. Ethnopharmacol. 2008; 166:403-406.
32. Mehrgan H, Mojab F, Pakdaman SH, Poursaeed M. Antibacterial activity of Thymus pubescens methanolic extract. Iran. J. Pharm. Res. 2008;7:291-298.
33. Zeghad N, Rachid M. Antioxidant and antibacterial activities of Thymus vulgaris L. Med. Aroma. Plant Res. J. 2013;1:5-11.
34. Fareed G, Afza N, Malik A, Versiani MA, Fareed N, Lateef M, Iqbal l, Mughal UR, Tareen RB.Phytochemical screening, total phenolic contents and biological evaluation of aerial parts of Nepeta praetervisa. J. Chem. Soci. Pak. 2013;35: 1364-1368.
35. Nadia Z, Rashid M. Antioxidant and antibacterial activities of Thymus vulgaris L. Med. and Aroma. Plant Res. J. 2013;1:5-11.
36. Hamdy Roby MH, Sarhan MA, Selim KAH, Khalel KI. Evaluation of antioxidant activity, total phenols and phenolic compounds in thyme (Thymus vulgaris L.), sage (Salvia officinalis L.) and marjoram (Origanum majorana L.) extracts. Indust. Crops Prod. 2013;43:827-831.
37. Nikolic M, Glamoclija J, Ferreira ICFR, Calhelha R, Fernandes A, Markovic T, Markovic D, Giweli A, Sokovic M. Chemical composition, antimicrobial, antioxidant and antitumor activity of Thymus serpyllum L., Thymus algerensis Boiss. and Reut and Thymus vulgaris L. essential oil. Indust. Crops Prod. 2014;52:183-190.
38. Soares JR, Dinis TC, Cunha AP, Almedia LM. Antioxidant activities of some extracts of Thymus zygis. Free Rad. Res. 1997;26:469-478.
39. Asadi Balsin Sharif Abad S, Nasri S, Amin G, Bidaran S. Anti-inflammatory and anti-nociceptive effects of hydroalchoholic extract of Nepeta menthoides on pain in aerial parts in male mice. J. Jahrom Univ. Med. Sci. 2013;11:1-9.
40. Sarahroodi S, Jafari-Najafi R, Nasri S, Rohampour K, Maleki-Jamshid A, Esmaeili S. Effects of Nepeta menthoides aqueous extract on retention and retrieval of memory in mice. Pak. J. Biol. Sci. 2012;15:1085-9.
41. Azizzadeh Delshad A, Parvizi M. The Neuroprotective effects of Nepeta menthoides on Axotomized Dorsal Root Ganglion sensory neurons in neonate rats. J. Basic Clin. Pathophysiol. 2014; 2:13-20.
42. Farjam MH, Mohammadi M, Izadi S, Barzegari F. Composition and antioxidant activity of the essential oils of Thymus trautvetteri Klokov &Desi-Shost, Thymus migricus Klokov&Des.-Shost and Thymus caespititus Brot. From Iran. Nat. Prod. 2013; 9:345-349.
43. Shahnazi S, Khalighi Sigaroodi F, Ajani Y, Yazdani D, Ahvazi M, Taghizad F. Study on chemical composition and antimicrobial activity of the essential oil of Thymus trautvetteri Klokov & Desi-Shost. J. Med. Plants. 2007;6:80-88. | ||
|
آمار تعداد مشاهده مقاله: 489 تعداد دریافت فایل اصل مقاله: 588 |
||