اخبار و اعلانات

 آمار

تعداد نشریات283
تعداد نشریات سازمان81
تعداد شماره‌ها2,727
تعداد مقالات31,057
تعداد مشاهده مقاله28,388,851
تعداد دریافت فایل اصل مقاله16,275,732
Mazandarani, Masoumeh. (1394). Autecology, Ethnopharmacology, Phytochemical, Antioxidant and Antimicrobial Activity of Thymus carmanicus Jalas. from Golestan Province in North of Iran. سامانه مدیریت نشریات علمی, 4(1), 67-75. doi: 10.22092/jmpb.2015.108893
Masoumeh Mazandarani. "Autecology, Ethnopharmacology, Phytochemical, Antioxidant and Antimicrobial Activity of Thymus carmanicus Jalas. from Golestan Province in North of Iran". سامانه مدیریت نشریات علمی, 4, 1, 1394, 67-75. doi: 10.22092/jmpb.2015.108893
Mazandarani, Masoumeh. (1394). 'Autecology, Ethnopharmacology, Phytochemical, Antioxidant and Antimicrobial Activity of Thymus carmanicus Jalas. from Golestan Province in North of Iran', سامانه مدیریت نشریات علمی, 4(1), pp. 67-75. doi: 10.22092/jmpb.2015.108893
Mazandarani, Masoumeh. Autecology, Ethnopharmacology, Phytochemical, Antioxidant and Antimicrobial Activity of Thymus carmanicus Jalas. from Golestan Province in North of Iran. سامانه مدیریت نشریات علمی, 1394; 4(1): 67-75. doi: 10.22092/jmpb.2015.108893

Autecology, Ethnopharmacology, Phytochemical, Antioxidant and Antimicrobial Activity of Thymus carmanicus Jalas. from Golestan Province in North of Iran

Journal of Medicinal plants and By-product
مقاله 10، دوره 4، شماره 1، تیر 2015، صفحه 67-75    اصل مقاله (202.62 K)
شناسه دیجیتال (DOI): 10.22092/jmpb.2015.108893
نویسنده
Masoumeh Mazandarani*
Department of Biology, Gorgan Branch, Islamic Azad University, Gorgan, Iran
چکیده
This research had been carried out to ecological characters, phytochemical, anti bacterial and antioxidant activity of Thymus carmanicus Jalas. in Golestan  province .In several field observation, the aerial parts of plant in blooming were collected from Deraznoo Mountain inSeptember 2013 (2700 m). Essential oil was obtained by hydro distillation and  analyzed by GC/MS. Phytochemical assay included: TP (total phenol) and TF (Total flavonoid) were determined by spectrophotometrically, antioxidant capacity were obtained by TAC, RP and DPPH methods and the antibacterial by using agar well method and the minimum inhibitory concentration (MIC) assay. Results showed that T. carmanicus is the most aromatic mountainous herb, which wild growing in cold dry climate (1800-2750 m) in Golestan province, with annual raining 30.5 mm, annual temperature 17.5 °C , in  sandy clay loam soil with pH= 7.5  and Ec=2.1  dc   and have long been used in traditional medicines of this region as a strong tonic, anti inflammation, carminative, anti virus, anti infection, anti fungus, anti ulcer and sedative . The carvacrol (41.4%), thymol (27.2%) and β-caryophylene were the major constituents of T. carmanicus oil , with total phenols (TP= 81.7±0.3 GAE/  g), total flavonoids (TF= 34.2±0.8 QUE/g), which had good antioxidant activity (IC50 = 21.8±0.1 µg/ml ), especially in DPPH method .The maximum activity of the essential oil was observed against Candida albicans ( 35.8±0.6 mm), S.epidermidis ( 33.1± 0.4 mm), B. subtilus ( 29.5± 0.2 mm), S.aureus ( 28.3±0.2 mm),  E.coli (23.1±0.4 mm), Enterococcus faecalis ( 17.2±0.8 mm) and Kelebsiella pneumoniae ( 16.5±0.2mm) with MIC value in the range of  10 - 132  mg/mL. According to these results, the aerial parts of plant have rich source of terpenoides , flavonoid and phenolic componds and showed  good antioxidant and antibacterial activity, which will be confirmed the traditional uses of T. carmanicus Jalas.  in these regions as an  good anti-inflammatory, sedative and anti infection.
کلیدواژه‌ها
Antioxidant؛ Autecology؛ essential oil؛ Ethnopharmacology؛ Golestan Province؛ TF and TP content؛ Golestan؛ Thymus carmanicus Jalas
مراجع

1. Mazandarani  M, Borhani  G, Fathiazad F. Phytochemical analysis, antioxidant activity and ecological requirements of Capparis spinosa L. in Golestan and Semnan provinces (North of Iran). J. Med. Plants By-prod. 2014; 1: 21-26.

2. Zarghami Moghaddam  P, Mazandarani M, Zolfaghari MR . Antibacterial and antioxidant activities of root extract of Onosma dichroanthum Boiss. in north of Iran. Afr. J. Microbiol. Res. 2012;6:1776-1781.

3. Zargari  A.  Medicinal Plants. Tehran, Iran: Tehran University Press, 1990;4:2842

4. Amin G.  Popular medicinal plants of Iran. Tehran, Iran: Tehran University of Medical Sciences Press. 2005.

5. Nejad Ebrahimi  S, Hadian b, Mirjalili MH, Sonboli C, Yousefzadie D. Essential oil composition and antibacterial activity of Thymus caramanicus at different phenological stages. Food Chem 110 .2008;927-931.

6. Sfaei-Ghomi  J, Meshkat alsadat  MH, Shamaei SH, Hashem Nejad M,  Hasani A. Chemical charachtirization of bioactive volatile molecoules of four Thymus species using nanoskale  injection method. Digest J. Nanomater. Biostruct. 2009; 4:835-841.

7. Hajimehdipoor  H, Khanavi M, Zahedi H, Abedi  Z, Kalantari Khandani N, Adib N, Pirali Hamedani M . Fingerprint Study of Thymus spp. by TLC. 2009;31:19-24.

8. Zenasni  L, Bakhy KH,  Gaboun  F,  Mousadak R, Benjouad AA,  Al Faiz SH. Essential oil composition and biomass productivity of Moroccan endemic Thymus satureioides Coss. & Ball. growing in the Agoundis Valley . J. Med. Plant Res. 2014;8: 504-512.

9. Karaman  S, Digrak  M, Ravid U,  Ilcim  A. Antibacterial and antifungal activity of the essential oils of Thymus revolutus Celak.  from Turkey. J. Ethnopharmacol. 2001;76:183-186.

10. Rasooli  I, Mirmostafa S A. Antibacterial properties of Thymus pubescens and Thymus serpyllum essential oils. Fitoterapia. 2002;73:244-250.

11. Rasooli I, Mirmostafa SA. Bacterial susceptibility to and chemical composition of essential oils from Thymus kotschyanus and Thymus persicus. J Agric Food Chem. 2003;51:2200-2205.

12. Miguel G, Simoes M, Figueiredo  AC,  Barroso J.G,  Pedro  LG, Carvalho  L .  Composition and antioxidant activities of the essential oils of Thymus caespititius, Thymus camphoratus and Thymus mastichina. Food Chemistry.2004;86:183-188.

13. Pourmorad  F,  Hosseinimehr  SJ,  Shahabimajd N . Antioxidant activity, phenol and flavonoid contents of some selected Iranian medicinal plants. Afr. J. Biotechnol. 2006;5:1142-1145.

14. Arabshahi-Delou  S,  Urooj  A. Antioxidant properties of various solvent extracts of mulberry (Morus indica L.) leaves.  Food Chem. 2007;102:1233-40.

15. Hammer KA,  Carson  CF,  Riley  TV. Antimicrobial activity of essential oils and other plant extracts. J. Appl. Microbiol.1999; 86:985-990.

16. Imelouane  B, Amhamdi H, Wathelet  JP, Ankit M,  Khedid  K,    Elbachiri  A. Chemical Composition and Antimicrobial Activity of Essential Oil of Thyme (Thymus vulgaris) from Eastern Morocco .Int. J. Agric. Biol. 2009;11:205-208.

17. Mazandarani, M, Osia N,  Ghafourian M.  Antioxidant activity and ethnopharmacological survey of Achillea biebersteinii Afan. in treatment of Dysmenorrhoea in traditional medicine of Golestan Province, Iran.  Int. J. Women’s Health Reprod. Sci. 2015; 3:107-110.

18. Mazandarani M,  Mirdeilami  S Z, Pessarakli  M. Essential oil composition and antibacterial activity of Achillea millefolium L. from different regions in North east of Iran. J. Med. Plants Res.2013;  7:1063-1069.

19. Ogbulie JN, Ogueke CC, Okoli IC, Anyanwu BN Antibacterial activities and toxicological potentials of crude ethanolic extracts of Euphorbia hirta. Afr. J. Biotechnol. 2007;6:1544-1548.

20. Mojab  F,  Nickavar B. Composition of the essential oils from three species from Labiatae from Iran. Planta Medica. 2006:72.

21. Rustaiyan  A,  Masoudi  SH,  Monfared  A,  Kamalinejad M,  Lajevardi T, Sedaghat S. Volatile constituents of three Thymus species grown wild in Iran.Planta Medica. 2000;66:197-198.

22. Sefidkon  F, Dabiri M, Mirmostafa S A. The essential oil of Thymus persicus (Ronniger ex Rech. f.) Jalas from Iran. J. Essent. Oil Res. 2002b;14:351-352.

23. Sadjadi S E, Khatamsaz M . Composition of the essential oil of Thymus daenensis Celak. ssp. lancifolius (Celak.) Jalas. J. Essent. Oil Res. 2003;15:34-35.

24. Knowles J R, Roller S, Murray DB, Naidu A S. Antimicrobial action of carvacrol at different stages of dual-species biofilm development by Staphylococcus aureus and Salmonella entericsero var. typhimurium. Appl. Environ. Microbiol.2005;71:797-803.

25. Kessler M, Ubeaud G, Jung L. Antiand pro‐oxidant activity of rutin and quercetin derivatives.J. Pharma. Pharmacol. 2003;55:131‐142

26. Zheng  W,    Wang SY. Antioxidant Activity and Phenolic Compounds in Selected Herbs. J. Agric. Food Chem. 2001;49:5165-5170.

27. Mozaffarian V. A dictionary of iranian plant names. 1996; N(5558):400.

آمار
تعداد مشاهده مقاله: 403
تعداد دریافت فایل اصل مقاله: 558


counter
سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب